Results 61 to 70 of about 4,022 (221)

MR‐Guidance of Gene Therapy for Brain Diseases: Moving From Palliative Treatment to Cures

open access: yesJournal of Magnetic Resonance Imaging, Volume 62, Issue 5, Page 1280-1295, November 2025.
ABSTRACT Regulatory bodies in the U.S. and Europe recently approved a gene therapy for aromatic L‐amino acid decarboxylase (AADC) deficiency, a rare neurologic disorder where a genetic mutation prevents dopamine production in the brain. Affected children fail to develop normal motor and cognitive functions.
Dalton H. Bermudez   +2 more
wiley   +1 more source

Distinct causal influences of parietal versus frontal areas on human visual cortex: evidence from concurrent TMS-fMRI [PDF]

open access: yes, 2010
It has often been proposed that regions of the human parietal and/or frontal lobe may modulate activity in visual cortex, for example, during selective attention or saccade preparation.
Bestmann, Sven   +7 more
core  

Precise Electrode Co‐Alignment in Deep Brain Stimulation Fusing Neuroimaging and Electrophysiology

open access: yesEuropean Journal of Neuroscience, Volume 62, Issue 10, November 2025.
ABSTRACT We present a multimodal framework to improve the precision of electrode placement in deep brain stimulation (DBS) by fusing preoperative neuroimaging with intraoperative electrophysiology for accurate electrode co‐alignment. The workflow integrates automated subthalamic nucleus (STN) segmentation from preoperative MRI using a two‐step ...
Igor Varga   +8 more
wiley   +1 more source

Ultrasonic Stereotaxis [PDF]

open access: yesThe Journal of the Acoustical Society of America, 1967
Ultrasonic visualization of human tissues has aimed at obtaining information simultaneously from a number of different depths from the surface. In consequence, only weakly focused transducers have been employed. In stereotaxic surgery when the highest possible accuracy is essential in three dimensions, it is preferable to sacrifice all other ...
openaire   +1 more source

Automated Marker Localization in the Planning Phase of Robotic Neurosurgery

open access: yesIEEE Access, 2017
Accurate patient registration is a critical issue in medical image-guided interventions. The neurosurgical robotic system RObotic Neuro-NAvigation (RONNA) uses four retro-reflective spheres, on a marker attached to the patient's cranial bone, for patient
Filip Suligoj   +4 more
doaj   +1 more source

Different strategies in the management of thalamic space-occupying lesions

open access: yesEgyptian Journal of Neurosurgery, 2020
Introduction Thalamic space-occupying lesions (SOL) are considered challenging for microsurgical removal. Unfortunately, the pathological features of lesions occurring in the thalamic region are different with a wide variation in clinical behavior and ...
Ahmed Abdel Aziz Fayed   +2 more
doaj   +1 more source

Dual enhancement mechanisms for overnight motor memory consolidation [PDF]

open access: yes, 2017
Our brains are constantly processing past events<sup>1</sup>. These offline processes consolidate memories, leading in the case of motor skill memories to an enhancement in performance between training sessions.
Breton, Jocelyn, Robertson, Edwin M.
core   +1 more source

The Next Frontier in Parkinson's Disease Treatment: A Narrative Review of Innovative Neurosurgical and Gene Therapy Approaches

open access: yesHealth Science Reports, Volume 8, Issue 9, September 2025.
ABSTRACT Background and Aims Parkinson's disease (PD) is a progressive neurological condition that consists of both motor and non‐motor symptoms that considerably deteriorate the quality of life. Pharmacological treatments, primarily levodopa, have been used to manage PD. However, side effects such as dyskinesias and motor fluctuations frequently limit
Muhammad Shaheer Bin Faheem   +6 more
wiley   +1 more source

Robot Assisted MRI-Guided LITT of the Anterior, Lateral, and Medial Temporal Lobe for Temporal Lobe Epilepsy

open access: yesFrontiers in Neurology, 2020
Robotic systems have fundamentally altered the landscape of functional neurosurgery. These allow automated stereotaxy with high accuracy and reliability, and are rapidly becoming a mainstay in stereotactic surgeries such as deep brain stimulation (DBS ...
Kunal Gupta   +6 more
doaj   +1 more source

Microbiota is essential for social development in the mouse [PDF]

open access: yes, 2013
No abstract ...
CG de Theije   +12 more
core   +1 more source

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