Results 61 to 70 of about 4,356 (249)

Blurring the Boundaries: An Investigation of Eating Disorder Recovery Content on TikTok

International Journal of Eating Disorders, EarlyView.
ABSTRACT Objective Eating disorder recovery content is widely circulated on TikTok. We thematically analyzed recovery content on TikTok, examined its associations with symptom severity among individuals with eating disorders, and assessed its co‐occurrence with pro‐eating disorder material within their TikTok feeds.
Scott Griffiths, Isabel Martyn, Harish Kannan, Ben Stone, Emma Austen, Edoardo Tescari, Usha Nattala, Wesley Grey, Noa Brittain, Deborah Mitchison, Jake Linardon, Jasmine Fardouly, Emily Harris   +12 more
wiley   +1 more source

Associations Between Self and Peer's Fear of Fat in Predicting Dietary Restraint, Weight/Shape/Eating Concerns, and Thin‐Ideal Internalization: A Dyadic Exploration in Female Friend Pairs

International Journal of Eating Disorders, EarlyView.
ABSTRACT Objective Fear of fat may reflect concern regarding rejection one may experience at a higher weight. Peers play a major role in socialization and support during adolescence and young adulthood. While studies have highlighted peers as an important source of influence underlying disordered eating, it is unclear whether one's own fear of fat or ...
Shannon M. O'Connor, Caroline G. Martin, Leora L. Haller, Shannon Marhan   +3 more
wiley   +1 more source

Behavior-related alterations of striatal neurochemistry in a mouse model of stereotyped movement disorder

Pharmacology Biochemistry and Behavior, 2004
Motor stereotypy is a common component of several developmental, genetic, and neuropsychiatric disorders. In animals, these behaviors can be induced or attenuated via pharmacological manipulation of specific neural loci comprising cortico basal ganglia-cortical feedback circuits, including the striatum.
Department of Neuroscience, University of Florida, Gainesville, FL 32610, USA ( host institution ), Presti, Michael F. ( author ), Watson, Christopher J. ( author ), Kennedy, Robert T. ( author ), Yang, Mark ( author ), Lewis, Mark H. ( author )   +5 more
openaire   +3 more sources

Seminars in epileptology: Holistic management of epilepsy in adults with intellectual development disorders

Epileptic Disorders, EarlyView.
Abstract This seminar addresses the complexity of the management of epilepsy in adults with intellectual development disorders (IDD), advocating holistic and multidisciplinary care aligned with the learning objectives of the International League Against Epilepsy. Epilepsy is significantly more prevalent in people with IDD, presenting unique diagnostic,
Elena Fonseca, Antonella Riva, Samuel López‐Maza, Malin Zaddach, Marie‐Claire Porter, Ingo Borggraefe, Lance Watkins, Andreas Schulze‐Bonhage, Rohit Shankar, Pasquale Striano, Lina Nashef   +10 more
wiley   +1 more source

Clinical utility and genetic landscape of exome sequencing in a large pediatric epilepsy cohort: Insights from a Turkish tertiary care center

Epileptic Disorders, EarlyView.
Abstract Objective To evaluate the diagnostic utility and genetic spectrum of next‐generation sequencing (NGS) in a large, well‐phenotyped cohort of Turkish pediatric patients with epilepsy of unknown etiology. Methods Between January 2021 and December 2024, 250 children (115 female, 135 male) with unexplained epilepsy underwent either whole‐exome ...
Derya Karaer, Beste Kipçak Yüzbaşı, İpek Şahin, Olcay Güngör, Kadri Karaer   +4 more
wiley   +1 more source

The small molecule simufilam dose‐dependently attenuates the worsening of seizures in a mouse model of tuberous sclerosis complex

Epilepsia, EarlyView.
Abstract Objective Novel epilepsy treatments for patients with tuberous sclerosis complex (TSC) and focal cortical dysplasia type II (FCDII) are urgently needed. In these patients, mutations in the mechanistic target of rapamycin (mTOR) pathway genes lead to mTOR hyperactivity and focal cortical malformations that frequently cause intractable epilepsy ...
Branden Stansley, Md. Monirul Islam, Dean J. Aguiar, Zoë Fuchs, Mackenzie Catron, Stephen Morairty, Ying Yuan, Radleigh Santos, Jingguo Hou, Annelies de Kater, George B. Thornton, Angelique Bordey   +11 more
wiley   +1 more source

Cognitive and behavioral clinical outcome assessments in children with developmental and epileptic encephalopathies: Issues and instruments

Epilepsia, EarlyView.
Abstract Children with developmental and epileptic encephalopathies (DEEs) face cognitive and behavioral challenges that may have a greater impact than seizures on their quality of life (QoL). The need to assess these nonseizure outcomes for evaluating treatments is increasingly recognized.
Cinzia Correale, Nicola Specchio, Jenny Downs, J. Helen Cross, Simona Cappelletti, Andrea Palacio‐Navarro, Sam Geuens, Kette Valente, Andreas Brunklaus, Colin Reilly   +9 more
wiley   +1 more source

Low dimensional temporal organization of spontaneous eye blinks in adults with developmental disabilities and stereotyped movement disorder

, 2010
This study investigated the mean rate and time-dependent sequential organization of spontaneous eye blinks in adults with intellectual and developmental disability (IDD) and individuals from this group that were additionally categorized with stereotypic ...
Bodfish, James W., Newell, Karl M., Lewis, Mark H., Lee, Mei-Hua   +3 more
core   +2 more sources

Artificial intelligence in preclinical epilepsy research: Current state, potential, and challenges

Epilepsia Open, EarlyView.
Abstract Preclinical translational epilepsy research uses animal models to better understand the mechanisms underlying epilepsy and its comorbidities, as well as to analyze and develop potential treatments that may mitigate this neurological disorder and its associated conditions. Artificial intelligence (AI) has emerged as a transformative tool across
Jesús Servando Medel‐Matus, Cesar Santana‐Gomez, Ruby G. Escalante, Dominique Duncan, Pedro F. Viana, Giulia Sofia Cereda, Naoto Kuroda, Aristea S. Galanopoulou   +7 more
wiley   +1 more source

Real‐world‐data for phenotypes and genotypes of rare monogenic genetic epilepsies and genes of uncertain significance for epilepsy

Epilepsia Open, EarlyView.
Abstract Objectives The objectives of this study were to develop a real‐world‐data (RWD) database for patients with epilepsy to provide further real‐world‐evidence (RWE) for monogenic genetic epilepsies; to assess the usefulness of a diagnostic algorithm in epilepsy; and to examine protein 3D structures using in silico tools to predict variant ...
Haley Morris, Elizabeth Mathew, Shalini Bahl, Marta Villa‐Lopez, Saadet Mercimek‐Andrews   +4 more
wiley   +1 more source