Results 41 to 50 of about 290,507 (301)

Organizing the interface—Plasma membrane architecture and receptor dynamics in virus‐cell interactions

open access: yesFEBS Letters, EarlyView.
Plasma membranes contain dynamic nanoscale domains that organize lipids and receptors. Because viruses operate at similar scales, this architecture shapes early infection steps, including attachment, receptor engagement, and entry. Using influenza A virus and HIV‐1 as examples, we highlight how receptor nanoclusters, multivalent glycan interactions ...
Jan Schlegel, Christian Sieben
wiley   +1 more source

Computationally synthesised inorganic and organometallic complexes : a thesis presented in partial fulfilment of the requirements of the degree of Doctor of Philosophy in Chemistry at Massey University, Albany, New Zealand [PDF]

open access: yes, 2017
Catalytic aromatic ring C–H bond functionalisations by transition metal cyclometallation reactions are important for organic transformation reactions.
Sajjad, Muhammad Arif
core  

Ruthenium-Based Heterocyclic Carbene-Coordinated Olefin Metathesis Catalysts [PDF]

open access: yes, 2010
The fascinating story of olefin (or alkene) metathesis (eq 1) began almost five decades ago, when Anderson and Merckling reported the first carbon-carbon double-bond rearrangement reaction in the titanium-catalyzed polymerization of norbornene.
Grubbs, Robert H.   +1 more
core   +1 more source

Engineering tandem VHHs to target different epitopes to enhance antibody‐dependent cell‐mediated cytotoxicity

open access: yesFEBS Open Bio, EarlyView.
Tandem VHH targeting distinct EGFR epitopes were engineered into a monovalent bispecific antibody (7D12‐EGA1‐Fc) with more potent ADCC without increasing affinity to EGFR. Structural modeling of 7D12‐EGA1‐Fc showed cross‐linking of separate EGFR domains to enhance CD16a engagement on NK cells.
Yuqiang Xu   +5 more
wiley   +1 more source

Steric Effects of Alcohols on the [Mn4O4] Cubane-Type Structures

open access: yesCrystals
[M4O4] (M = 3d transition metal) represents an interesting class of compounds featuring cubane-type molecular structures, and particularly, [Mn4O4] cubanes or their derivatives attract much attention by virtue of their potential applications as single ...
Yan He, Zheng Zhou, Haixiang Han
doaj   +1 more source

Solid State Structure and Solution Thermodynamics of Three-Centered Hydrogen Bonds (O∙∙∙H∙∙∙O) Using N-(2-Benzoyl-phenyl) Oxalyl Derivatives as Model Compounds

open access: yesMolecules, 2014
Intramolecular hydrogen bond (HB) formation was analyzed in the model compounds N-(2-benzoylphenyl)acetamide, N-(2-benzoylphenyl)oxalamate and N1,N2-bis(2-benzoylphenyl)oxalamide.
Carlos Z. Gómez-Castro   +5 more
doaj   +1 more source

N-Glycans Mediate the Ebola Virus-GP1 Shielding of Ligands to Immune Receptors and Immune Evasion

open access: yesFrontiers in Cellular and Infection Microbiology, 2020
The Ebola Virus (EBOV) glycoprotein (GP) sterically shields cell-membrane ligands to immune receptors such as human leukocyte antigen class-1 (HLA-I) and MHC class I polypeptide-related sequence A (MICA), thus mediating immunity evasion. It was suggested
Muhammed Iraqi   +12 more
doaj   +1 more source

Sea Surface Height Changes due to the Tropical Cyclone-Induced Water Mixing in the Yellow Sea, Korea

open access: yesFrontiers in Earth Science, 2022
Sea surface height changes due to the tropical cyclone (TC)-induced water mixing in the Yellow Sea, Korea, were investigated using temperature and salinity profile data obtained by two Argo floats during the summer and fall of 2018 and 2020. Strong winds
KiRyong Kang, Il-Ju Moon
doaj   +1 more source

Active Matter Ratchets with an External Drift

open access: yes, 2013
When active matter particles such as swimming bacteria are placed in an asymmetric array of funnels, it has been shown that a ratchet effect can occur even in the absence of an external drive. Here we examine active ratchets for two dimensional arrays of
Reichhardt, C., Reichhardt, C. J. Olson
core   +1 more source

dUTPase is essential in zebrafish development and possesses several single‐nucleotide variants with pronounced structural and functional consequences

open access: yesFEBS Open Bio, EarlyView.
dUTPases are involved in balancing the appropriate nucleotide pools. We showed that dUTPase is essential for normal development in zebrafish. The different zebrafish genomes contain several single‐nucleotide variations (SNPs) of the dut gene. One of the dUTPase variants displayed drastically lower protein stability and catalytic efficiency as compared ...
Viktória Perey‐Simon   +6 more
wiley   +1 more source

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