Results 71 to 80 of about 9,420,423 (308)

Observation of 1,3-Diketones Formation in the Reaction of Bulky Acyl Chlorides with Methyllithium

open access: yesMolecules, 2012
The formation of 1,3-diketones was observed in the reactions of bulky acyl chlorides with methyllithium. The reaction products depend on the steric hindrance around the carbonyl group of the acyl chloride and the electronic effect of the group(s) linked ...
Liwen Yang, Nianfa Yang, Jian Zhang
doaj   +1 more source

Structural studies and functional engineering of NanX: an anhydro‐sialic acid transporter from Escherichia coli

open access: yesFEBS Open Bio, EarlyView.
Biophysical characterisation shows that NanX, a membrane transport protein from the major facilitator superfamily (MFS), forms both monomers and dimers after purification. AlphaFold modelling and substrate docking provide information on residues likely involved in substrate recognition for NanX and another MFS member, NanT.
Michael C. Newton‐Vesty   +13 more
wiley   +1 more source

In silico and in vitro exploration of a tyrosinase for biocatalytic production of catechols

open access: yesFEBS Open Bio, EarlyView.
Tyrosinase from Ralstonia pseudosolanacearum is a promising biocatalyst for producing valuable catechols from monophenol substrates. This tyrosinase is uniquely suited to this due to its high monophenolase : diphenolase ratio. We combined in silico docking and in vivo kinetic characterisation of this tyrosinase with 11 industrially relevant monophenols,
James Britton   +6 more
wiley   +1 more source

A Dramatic Steric Effect on the Rate of Migratory CO Insertion on Rhodium

open access: yes, 2016
A Dramatic Steric Effect on the Rate of Migratory CO Insertion on ...
Luca Gonsalvi (1676023)   +4 more
core   +1 more source

Structural and biochemical insights into the thermostable esterase Ta0887 from Thermoplasma acidophilum

open access: yesFEBS Open Bio, EarlyView.
In this study, a novel esterase from the thermoacidophilic archaeon Thermoplasma acidophilum was biochemically and structurally characterized. Our results demonstrate that Ta0887 is a highly thermostable esterase that preferentially hydrolyzes p‐nitrophenyl hexanoate and possesses an α‐helical cap domain that likely contributes to its substrate ...
Alejandro Delgado‐Rey   +4 more
wiley   +1 more source

Modeling of arsenic rejection considering affinity and steric hindrance effect in nanofiltration membranes

open access: yes, 2000
Rejection characteristics of arsenic compounds such as arsenite, dimethyl arsinic acid, and arsenate were examined regarding the effect of pH change in nanofiltration.
H. Kitawaki   +5 more
core   +1 more source

How Might Exodus Effect Assist Users?

open access: yes, 2022
Exodus Effect approach is rather than something THC supply gave to people. CBD (in any structure) animates receptor webweb destinations withinside the endocannabinoids while consumed.
Exodus Effect
core   +1 more source

Genetic dissection of human ABCE1 in yeast reveals separable requirements for ribosome recycling and suppression of aberrant reinitiation

open access: yesFEBS Open Bio, EarlyView.
Human ABCE1 cannot functionally replace its yeast ortholog. Yeast–human chimera analysis identified NBD1 as a major interspecies barrier. Genetic screening yielded hABCE1 revertants that rescue yeast viability but fail to suppress aberrant translation reinitiation in the 3′ UTR.
Eriko Nakata   +3 more
wiley   +1 more source

Very Strong Hydrogen Bond in Nitrophthalic Cocrystals

open access: yesMolecules
This work presents the studies of a very strong hydrogen bond (VSHB) in biologically active phthalic acids. Research on VSHB comes topical due to its participation in many biological processes.
Kinga Jóźwiak   +5 more
doaj   +1 more source

Steric Effect of Protonated Tertiary Amine in Primary–Tertiary Diamine Catalysis: A Double-Layered Sterimol Model

open access: yes, 2018
Steric shielding effects are seldom adopted in the stereocontrol with chiral primary amine catalysts. An unexpected steric shielding effect of protonated tertiary amine, a typical hydrogen-bonding moiety, was disclosed.
Yaning Wang (2997282)   +5 more
core   +1 more source

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