Results 91 to 100 of about 351,681 (398)

Combining antibody conjugates with cytotoxic and immune‐stimulating payloads maximizes anti‐cancer activity

open access: yesMolecular Oncology, EarlyView.
Methods to improve antibody–drug conjugate (ADC) treatment durability in cancer therapy are needed. We utilized ADCs and immune‐stimulating antibody conjugates (ISACs), which are made from two non‐competitive antibodies, to enhance the entry of toxic payloads into cancer cells and deliver immunostimulatory agents into immune cells.
Tiexin Wang   +3 more
wiley   +1 more source

The Effect of X-Rays on Cytological Traits of Tuta absoluta (Lepidoptera: Gelechiidae) [PDF]

open access: yes, 2016
The tomato leafminer, Tuta absoluta (Meyrick) (Lepidoptera: Gelechiidae) is one of the most important pests of tomato. With the purpose of developing environmentally friendly control tactics such as the inherited sterility (IS) technique against this ...
Cagnotti, Cynthia Lorena   +5 more
core   +1 more source

A review of rice male sterility types and their sterility mechanisms

open access: yesHeliyon, 2023
Yusheng Xu   +3 more
semanticscholar   +1 more source

Homologous expression and purification of human HAX‐1 for structural studies

open access: yesFEBS Open Bio, EarlyView.
This research protocol provides detailed instructions for cloning, expressing, and purifying large quantities of the intrinsically disordered human HAX‐1 protein, N‐terminally fused to a cleavable superfolder GFP, from mammalian cells. HAX‐1 is predicted to undergo posttranslational modifications and to interact with membranes, various cellular ...
Mariana Grieben
wiley   +1 more source

A systematic map of studies testing the relationship between temperature and animal reproduction

open access: yesEcological Solutions and Evidence
Exposure to extreme temperatures can negatively affect animal reproduction, by disrupting the ability of individuals to produce any offspring (fertility), or the number of offspring produced by fertile individuals (fecundity).
Liam R. Dougherty   +43 more
doaj   +1 more source

Interspecies Hybridisation and Genome Chimerisation in Saccharomyces: Combining of Gene Pools of Species and Its Biotechnological Perspectives

open access: yesFrontiers in Microbiology, 2018
Over the last one and a half decade, interspecies hybridisation has gained continuously increasing attention as a breeding technique suitable for transferring of genetic information between Saccharomyces species and mixing of their gene pools without ...
Matthias Sipiczki
doaj   +1 more source

Reassessing Canonical Attitudes Towards African Marriage Practices Based on a Study of the African Synod [PDF]

open access: yes, 1996
African theologians are virtually unanimous in pointing out that the experience and institution of marriage constitute a special test case for the process of inculturation in the Church in Africa.
Orobator, Agbonkhianmeghe E.
core   +1 more source

Forced Sterilization

open access: yesVoices in Bioethics, 2022
Photo by Renè Müller on Unsplash INTRODUCTION Forced sterilization of women around the globe is a human rights violation and bioethical concern. In the past, countries enacted laws to forcibly sterilize women deemed unfit to procreate. Although many of these laws have been retracted, the practice persists under the guise of public health. More recently,
openaire   +3 more sources

Long‐term culture of skin biopsies: maintenance of fibroblast production and competency of reprogramming

open access: yesFEBS Open Bio, EarlyView.
Skin biopsies taken from a patient with an ultra‐rare disorder as well as controls were cultured for up to 473 days. The chunks of skin were serially transferred to a new culture plate when confluent with fibroblasts. Different generations of fibroblasts were analyzed for cell and molecular properties, proliferation, and competence for reprogramming to
Sudiksha Rathan‐Kumar   +3 more
wiley   +1 more source

RECONSTRUCTIVE AND STABILIZING ABILITY OF THE MAIZE LINES IN STERILE CYTOPLASM “M” AND “C” TYPES OF CMS

open access: yesЗерновое хозяйство России, 2019
Seeds of maize hybrids in the Russian Federation are obtained using CMS, therefore it is necessary to transfer the developed hybrids to a sterile basis to introduce them into production. The purpose of the work is to study the reaction of self-pollinated
G. Ya. Krivosheev, A. S. Ignatiev
doaj   +1 more source

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