NPM1 selectively sorts specific mRNAs into extracellular vesicles (EVs) by recognizing RNA motifs and forming phase‐separated condensates. These mRNA cargos—including EGFR—are then loaded via multivesicular bodies. This active sorting pathway, validated in EVs derived from both lung cancer cells and patient serum, reveals a specific mechanism for ...
Kaixiang Zhang +8 more
wiley +1 more source
Contraceptives in chronic lymphocytic leukemia (CLL): a narrative review. [PDF]
Al-Shibly R +4 more
europepmc +1 more source
[Forced sterilizations, reproductive rights and informed consent].
openaire +1 more source
Size‐Modulated Mesoderm‐Endoderm Divergence and Myocardial Cavitation in Micropatterned Cardioids
Micropatterned cardioids, CRISPR‐engineered reporter hiPSCs, deep‐tissue imaging, and single‐cell RNA sequencing are integrated to model mesoderm‐endoderm co‐development. Heart‐foregut crosstalk promotes single large cavitation inside cardioids, resembling early heart chamber formation. ABSTRACT The human heart, originating from the splanchnic mesoderm,
Plansky Hoang +12 more
wiley +1 more source
Postpartum Sterilization after a Preterm Delivery Is Not Associated with Decision Regret. [PDF]
Toscano M +4 more
europepmc +1 more source
A healthy gut barrier shields underlying fibroblasts from luminal shear forces, illustrating that “good fences make good neighbors.” Barrier damage exposes fibroblasts to shear stress, inducing cell death and the emergence of stress‐adapted, profibrotic fibroblasts. Sustained shear exposure promotes the formation of stiff aggregates of mechanoadapative
Soyoun Min +6 more
wiley +1 more source
Comparison of reproductive outcomes after laparoscopic tubal anastomosis using conventional (non-barbed) sutures and barbed sutures. [PDF]
Karadag C, Karadag B.
europepmc +1 more source
A Nanoparticle‐Integrated Complete Manufacturing Pipeline of Chemically Engineered Exosomes
We report a novel manufacture technology of chemically engineered exosomes. The four steps of manufacturing, i.e., biogenesis, loading, isolation, and storage, are integrated by the use of a nanoparticle. The manufacture technology incorporates three innovative components, i.e., a new nano‐bio effect, a new composite nanoparticle, and a new isolation ...
Xiaowei Wen +13 more
wiley +1 more source
Pomeroy Sterilization in a Teen with Recurrent Pregnancy and Multiple Cesarean Deliveries: A Case Report. [PDF]
Nurdiawan W +7 more
europepmc +1 more source
Population, Rhythm, Contraception and Abortion Policy Questions [PDF]
Hellegers, Andre E.
core +1 more source

