Results 51 to 60 of about 124,098 (337)

BMP antagonist CHRDL2 enhances the cancer stem‐cell phenotype and increases chemotherapy resistance in colorectal cancer

open access: yesMolecular Oncology, EarlyView.
Overexpression of CHRDL2 in colon cancer cells makes them more stem‐like and resistant to chemo‐ and radiotherapy. CHRDL2‐high cells have upregulation of the WNT pathway, genes involved in the DNA damage response (DDR) pathway and epithelial‐to‐mesenchymal transition (EMT). This leads to quicker repair of damaged DNA and more cell migration.
Eloise Clarkson, Annabelle Lewis
wiley   +1 more source

Effect of Different Sterilization Treatments on the Nutrition and Taste of Soft Canned Saury

open access: yesShipin gongye ke-ji, 2023
The potential of ultra-high-pressure sterilization combined with olive oil impregnation for the processing of soft canned saury was evaluated in this paper.
Mei ZHANG   +4 more
doaj   +1 more source

Sterile neutrino production in models with low reheating temperatures [PDF]

open access: yesJHEP 0706:002,2007, 2007
By numerically solving the appropriate Boltzmann equations, we study the production of sterile neutrinos in models with low reheating temperatures. We take into account the production in oscillations as well as in direct decays and compute the sterile neutrino primordial spectrum, the effective number of neutrino species, and the sterile neutrino ...
arxiv   +1 more source

Tumor clusters with divergent inflammation and human retroelement expression determine the clinical outcome of patients with serous ovarian cancer

open access: yesMolecular Oncology, EarlyView.
Analysis of treatment‐naïve high‐grade serous ovarian carcinoma (HGSOC) and control tissues for ERVs, LINE‐1 (L1), inflammation, and immune checkpoints identified five clusters with diverse patient recurrence‐free survivals. An inflammation score was calculated and correlated with retroelement expression, where one novel cluster (Triple‐I) with high ...
Laura Glossner   +6 more
wiley   +1 more source

405 nm violet-blue light inactivates hepatitis C cell culture virus (HCVcc) in ex vivo human platelet concentrates and plasma

open access: yesScientific Reports
Added safety measures coupled with the development and use of pathogen reduction technologies (PRT) significantly reduces the risk of transfusion-transmitted infections (TTIs) from blood products.
Joseph W. Jackson   +7 more
doaj   +1 more source

Sterile neutrinos in cosmology [PDF]

open access: yesPhysics Reports, Volumes 711-712, 10 November 2017, Pages 1-28, 2017
Sterile neutrinos are natural extensions to the standard model of particle physics in neutrino mass generation mechanisms. If they are relatively light, less than approximately 10 keV, they can alter cosmology significantly, from the early Universe to the matter and radiation energy density today.
arxiv   +1 more source

KCS1 and VIP1, the genes encoding yeast phosphoinositol pyrophosphate synthases, are required for Ca2+‐mediated response to dimethylsulfoxide (DMSO)

open access: yesFEBS Open Bio, EarlyView.
Ca2+‐mediated response to DMSO was investigated in Saccharomyces cerevisiae cells expressing Ca2+‐dependent aequorin. Cell exposure to DMSO induced a cytosolic Ca2+ wave dependent on the integrity of the Cch1/Mid1 channel. Deletion of KCS1 or VIP1 genes encoding the phosphoinositol pyrophosphate (PP‐IP) synthases suppressed the DMSO‐induced Ca2 ...
Larisa Ioana Gogianu   +4 more
wiley   +1 more source

Sterilization incentives and associated regret among ever married women in India, NFHS, 2015–16

open access: yesBMC Health Services Research, 2022
Objective Sterilization is the only family planning method that involves relatively large amount compensation. So, the study attempts to examine the role of incentives received against the sterilization procedures on the reporting of sterilization regret
Anjali Bansal   +2 more
doaj   +1 more source

Measuring the Sterile Neutrino CP Phase at DUNE and T2HK [PDF]

open access: yesEur.Phys.J. C78 (2018) no.4, 339, 2017
The CP phases associated with the sterile neutrino cannot be measured in the dedicated short-baseline experiments being built to test the sterile neutrino hypothesis. On the other hand, these phases can be measured in long-baseline experiments, even though the main goal of these experiments is not to test or measure sterile neutrino parameters.
arxiv   +1 more source

Iron‐dependent lysosomal LDL oxidation induces the expression of scavenger receptor A in human THP‐1 monocytes

open access: yesFEBS Open Bio, EarlyView.
In human monocytic cells THP‐1, a limited uptake of native—not oxidized—LDL/VLDL induced expression of scavenger receptor A and cellular adhesion. Induction was inhibited by lysosomotropic (WR‐1065) and lipophilic (BHT) antioxidants and by siRNAs against ferritinophagy.
Martina Čierna   +4 more
wiley   +1 more source

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