MAGEA6 Engages a YY1‐Dependent Transcription to Dictate Perineural Invasion in Colorectal Cancer
Advanced Science, EarlyView.This study investigates the role of MAGEA6 in perineural invasion (PNI) in colorectal cancer (CRC). MAGEA6 promotes CRC invasiveness by inhibiting YY1 ubiquitination, enhancing CXCL1 secretion, and recruiting Schwann cells. These findings highlight the potential of targeting the MAGEA6/YY1/CXCL1 axis for therapeutic strategies against PNI and tumor ...
Hao Wang +9 more
wiley +1 more source
Post-vasectomy Pain Syndrome: A Review of the Literature and Updated Treatment Algorithm. [PDF]
CureusUrbanski M +3 more
europepmc +1 more source
Advanced Science, EarlyView.How locus coeruleus noradrenergic‐spinal projections and subsequent α2A adrenoceptors‐CaMKII signaling cascades contribute to electroacupuncture‐induced antinociception in postoperative pain in mice is described. Abstract Postoperative pain remains a significant challenge in healthcare.
Wen‐Guang Chu +13 more
wiley +1 more source
Protocol for artificial intelligence-guided neural control using deep reinforcement learning and infrared neural stimulation. [PDF]
STAR ProtocCoventry BS, Bartlett EL.
europepmc +1 more source
Population Control in Puerto Rico: The Formal and Informal Framework [PDF]
, 1960 Back, Kurt W. +2 more
core +2 more sources
Lignin‐Based Photothermal Materials: Bridging Sustainability and High‐Efficiency Energy Conversion
Advanced Science, EarlyView.This review provides new perspectives on lignin‐based photothermal materials, emphasizing their molecular structure for efficient energy conversion. It summarizes mechanisms and strategies for improving photothermal efficiency in applications of photothermal actuation, desalination, and biomedical therapies.
Zhiwen Sun +10 more
wiley +1 more source
Sterilization of free-ranging female capybaras (Hydrochoerus hydrochaeris): a comparison between two surgical techniques. [PDF]
Anim ReprodJorge FMG +11 more
europepmc +1 more source
HDAC6 and USP9X Control Glutamine Metabolism by Stabilizing GS to Promote Glioblastoma Tumorigenesis
Advanced Science, EarlyView.Glioblastoma (GBM) growth relies on glutamine synthetase (GS), which is stabilized by histone deacetylase 6 (HDAC6) and deubiquitinated by ubiquitin‐specific peptidase 9, X‐linked (USP9X). HDAC6 promotes GS deacetylation, while USP9X removes its K48‐linked polyubiquitination, enhancing GS stability.
Go Woon Kim +9 more
wiley +1 more source
Where Microsurgical Tubal Reanastomosis Stands in the In vitro Fertilization Era. [PDF]
Gynecol Minim Invasive TherMoon HS, Joo BS, Kim SG, Nam KI, Koo JS.
europepmc +1 more source
Advanced Science, EarlyView.Bubbles in soft tissue are the unavoidable consequence of magnesium implant degradation in patients, yet their biological significance remains unclear. Using advanced imaging and spatial transcriptomics, this study reveals a pronounced inflammatory and mechanical response near bubbles, contrasting with pro‐regenerative events closer to the implant ...
Heithem Ben Amara +3 more
wiley +1 more source