G3BP1 Succinylation at K413 is Critical for Cardiac Function by Modulating PI3K‐AKT‐mTOR Signal Axis
Schematic illustrating the impact of G3BP1 succinylation at K413 on cardiac function. In the healthy human heart, G3BP1 succinylation maintains homeostatic mTOR signaling. In patients with dilated cardiomyopathy (DCM) and heart failure (HF), G3BP1 de‐succinylation induces RagA expression and disrupts the binding of the TSC1/2 complex, leading to the ...
Yuan Zhang +9 more
wiley +1 more source
Combination of Upper Thoracic Fracture and Sternum Fracture
Introduction The upper thoracic spine differs from other regions of the spine for extra stability given by the complex rib sternum. Isolated fractures of the sternum are considered harmless.
Pedro Bazan +4 more
doaj +1 more source
Stairlike fracture of the sternum [PDF]
A 30-year-old man, who had been involved in a traffic collision four hours previously, was transferred to our university hospital from a rural hospital. He was not wearing a seat belt while driving and had an isolated sternal fracture with severe displacement after hitting the steering wheel ([
AYDIN, Yener, Sade, Recep
openaire +3 more sources
A one‐step, asymmetric reductive coupling of alkynes and oxa‐ and aza‐bicyclic olefins using a cobalt/photoredox catalytic system through desymmetrization. ABSTRACT Bicyclo[2.2.1]heptane frameworks represent a privileged structural motif prevalent in numerous natural products and bioactive molecules.
Subhankar Pradhan +5 more
wiley +1 more source
Ectopia cordis : a report of two cases in Cameroon [PDF]
This article reports two cases of ectopia cordis in two children aged one day and twenty months respectively. A one day old newborn had complete thoracic ectopia cordis associated with an internal cardiac defect and severe thoracic and abdominal wall ...
Mbassi Awa, Hubert Desire +6 more
core
A fascinating case of a huge aortic pseudoaneurysm protruding subcutaneously through the sternum
An 89 year-old female presented with a slightly tender mass on her sternum (Panel 1). She had been complaining of a mild, dull ache in her chest for a few months prior to her presentation.
Aroney, Greg +3 more
core +1 more source
Impedance of Nonelectroneutral Solid Electrolyte Interphases With Nanopores: A Theoretical Model
Physical modeling reveals that often‐neglected non‐electroneutrality and nanopores in the solid‐electrolyte interphase (SEI) govern the impedance behavior. Under nonreactive conditions, the low‐frequency constant‐phase element (CPE) phenomenon can be attributed to the nonelectroneutral local conditions in the SEI.
Chenkun Li, Jun Huang
wiley +1 more source
Morphogenesis of the manubrium of sternum in human embryos: a new concept
To revisit many theories on fetal development of the manubrium of the sternum, we examined 25 mid-term fetuses at 6-9 weeks of gestation. The initial developmental stage of the manubrium was characterized by a distinct interclavicular mesenchyme that was
Verdugo López, Samuel +4 more
core +1 more source
Photocatalytic Synthesis of Pentafluorosulfanyl Ketones, Acetals, and BCP Motifs Utilizing SF6
A photocatalytic single electron reduction strategy is reported for the activation and valorization of sulfur hexafluoride (SF6), a potent greenhouse gas. Under mild conditions, SF6 is reduced to generate pentafluorosulfanyl (SF5) radicals, enabling direct access to pentafluorosulfanyl ketones, acetals, and BCP motifs.
Chen‐Hui Jiang +11 more
wiley +1 more source
Radiologic assessment of the optimal point for tube thoracostomy using the sternum as a landmark: a computed tomography‐based analysis [PDF]
Purpose This study aimed at developing a novel tube thoracostomy technique using the sternum, a fixed anatomical structure, as an indicator to reduce the possibility of incorrect chest tube positioning and complications in patients with chest trauma ...
Jaeik Jang +8 more
doaj +1 more source

