Results 51 to 60 of about 452,915 (259)

Unraveling the molecular mechanisms of cell migration impairment and apoptosis associated with steroid sulfatase deficiency: Implications for X-linked ichthyosis

Biochimica et Biophysica Acta - Molecular Basis of Disease
Tae-Uk Kwon, Yeo‐Jung Kwon, Hyoung‐Seok Baek, Hyemin Park, Hyein Lee, Young‐Jin Chun   +5 more
openalex   +2 more sources

Inhibition of Steroid Sulfatase Activity in Endometriotic Implants by STX64 (667Coumate): A Potential New Therapy [PDF]

The Scientific World Journal, 2008
L. Fusi, A. Purohit, J. Brosens, L. W. L. Woo, B. V. L. Potter, M. J. Reed   +5 more
doaj   +2 more sources

RNA sequencing and lipidomics uncovers novel pathomechanisms in recessive X-linked ichthyosis

Frontiers in Molecular Biosciences, 2023
Recessive X-linked ichthyosis (RXLI), a genetic disorder caused by deletion or point mutations of the steroid sulfatase (STS) gene, is the second most common form of ichthyosis.
Farrell McGeoghan, Emanuela Camera, Miriam Maiellaro, Manasi Menon, Mei Huang, Priya Dewan, Stela Ziaj, Matthew P. Caley, Michael Donaldson, Anton J. Enright, Edel A. O’Toole, Edel A. O’Toole   +11 more
doaj   +1 more source

Reduced Dehydroepiandrosterone-Sulfate Levels in the Mid-Luteal Subphase of the Menstrual Cycle: Implications to Women’s Health Research

Metabolites, 2022
The regulation of DHEA-sulfate by steroid sulfotransferase (SULT) and steryl-sulfatase (STS) enzymes is a vital process for the downstream formation of many steroid hormones. DHEA-sulfate is the most abundant steroid hormone in the human body; thus, DHEA-
Ajna Hamidovic, Fatimata Soumare, Aamina Naveed, John Davis, Jiehuan Sun, Nhan Dang   +5 more
doaj   +1 more source

Steroid Sulfatase in the Human Hair Follicle Concentrates in the Dermal Papilla [PDF]

, 2001
5α-dihydrotestosterone is known to play a crucial part in the regulation of hair growth and in the development of androgenetic alopecia. 5α-dihydrotestosterone is formed locally within the hair follicle from the systemic precursor testosterone by ...
Rolf Hoffmann, Shiro Niiyama, Antal Rot, Andreas Billich   +3 more
openalex   +3 more sources

Profiling Urinary Sulfate Metabolites With Mass Spectrometry

Frontiers in Molecular Biosciences, 2022
The study of urinary phase II sulfate metabolites is central to understanding the role and fate of endogenous and exogenous compounds in biological systems.
Christopher C. J. Fitzgerald, Rikard Hedman, Dimanthi R. Uduwela, Bettina Paszerbovics, Adam J. Carroll, Teresa Neeman, Adam Cawley, Lance Brooker, Malcolm D. McLeod   +8 more
doaj   +1 more source

The Uptake and Deconjugation of Androstenone Sulfate in the Adipose Tissue of the Boar

Animals, 2021
Boars express high testicular levels of sulfotransferase enzymes, and consequently, the boar taint causing compound androstenone predominantly circulates as a steroid sulfate.
Christine Bone, E. James Squires
doaj   +1 more source

In the Model Cell Lines of Moderately and Poorly Differentiated Endometrial Carcinoma, Estrogens Can Be Formed via the Sulfatase Pathway

Frontiers in Molecular Biosciences, 2021
Endometrial cancer (EC) is the most common gynecological malignancy in resource-abundant countries. The majority of EC cases are estrogen dependent but the mechanisms of estrogen biosynthesis and oxidative metabolism and estrogen action are not ...
Renata Pavlič, Marija Gjorgoska, Eva Hafner, Maša Sinreih, Kristina Gajser, Stefan Poschner, Walter Jäger, Tea Lanišnik Rižner   +7 more
doaj   +1 more source

Characterization of iodothyronine sulfatase activities in human and rat liver and placenta [PDF]

, 2002
In conditions associated with high serum iodothyronine sulfate concentrations, e.g. during fetal development, desulfation of these conjugates may be important in the regulation of thyroid hormone homeostasis. However, little is known
Coughtrie, M.W., Dijk, C.H. (Caren) van, Kaptein, E. (Ellen), Kester, M.H.A. (Monique), Roest, T.J. (Thirza), Tibboel, D. (Dick), Visser, T.J. (Theo)   +6 more
core   +2 more sources

Brain gene expression in a novel mouse model of postpartum mood disorder

Translational Neuroscience, 2019
Steroid sulfatase (STS) cleaves sulfate groups from steroid hormones; its expression/activity increases in late pregnancy and into the postpartum period.
Humby Trevor, Davies William
doaj   +1 more source