Results 131 to 140 of about 464,115 (319)

An Unusual Case of Herpes Simplex Viral Encephalitis Following Acute Retinal Necrosis after Administration of a Systemic Steroid [PDF]

, 1970
Sang Jin Kim, Se Woong Kang, Eun Yeon Joo   +2 more
openalex   +1 more source

Targeting NRP1 in Endothelial Cells Facilitates the Normalization of Scar Vessels and Prevents Fibrotic Scarring

Advanced Science, EarlyView.
Scars exhibit vascular abnormal alterations, including upregulated NRP1 expression in endothelial cells, increased vascular density and branching, compromised vessel wall integrity, and incomplete pericyte coverage. Therapeutic targeting of NRP1 through hydrogel spray delivery offers a promising approach to normalize aberrant vasculature and prevent ...
Yu Wang, Xin Zhou, Min Liu, Meimei Huang, Peirong Chen, Xinying Li, Fangchao Xue, Wenyan Zhao, Di Liu, Lang Li, Yuangang Lu, Wen Zeng   +11 more
wiley   +1 more source

Steroidal Compounds at the Crossroads of Inflammation and Cancer: Implications for Drug Discovery and Therapy. [PDF]

Biomedicines
Dembitsky VM, Terent'ev AO.
europepmc   +1 more source

Stromal Steroid 5 Alpha-Reductase 2 Promotes Prostate Growth through WNT5A–Lymphoid Enhancer–Binding Factor 1–Insulin-Like Growth Factor 1 Signaling in Benign Prostatic Hyperplasia

Christina Sharkey, Boqing Gu, Xingbo Long, Yaoliang Tang, Nicolas Patsatzis, Steven Li, Aria F. Olumi, Zongwei Wang   +7 more
openalex   +2 more sources

p16Ink4a‐Positive Hepatocytes Drive Liver Fibrosis Through Activation of LIFR Family Pathway

Advanced Science, EarlyView.
This study found that, following the long‐term CCl4 treatment, p16high hepatocytes appeared in zone 3, spatially co‐localizing with fibrotic areas. A specific cluster of p16high hepatocytes upregulated CTF1/LIF expression which induced HSC activation and further liver fibrosis, as revealed by single cell transcriptomic analysis.
Koji Nishikawa, Teh‐Wei Wang, Satoshi Kawakami, Shota Tanimoto, Kiyoshi Yamaguchi, Taketomo Kido, Masamichi Kimura, Tsunekazu Hishima, Yuki T. Okamura, Satotaka Omori, Takumi Iritani, Toshikaze Chiba, Takehiro Jimbo, Michio Katano, Kansuporn Kamataki, Ryoichi Yokoyama, Eigo Shimizu, Kiminori Kimura, Satoshi Yamzaki, Seiya Imoto, Yoichi Furukawa, Atsushi Miyajima, Yoshikazu Johmura, Makoto Nakanishi   +23 more
wiley   +1 more source

Patterns of steroid use in patients with established rheumatoid arthritis commencing treatment with biologic or targeted synthetic DMARDs. [PDF]

Rheumatol Adv Pract
Stadler M, Bindra S, Cheung A, Yap CF, Bluett J, Plant D, Nair N, Hyrich K, Morgan A, Wilson AG, Isaacs JD, Barton A.   +11 more
europepmc   +1 more source

A Biomarker‐Driven Ovary–Endometrium Organ‐on‐a‐Chip Mimicking 3D Multicellular Complexity and Menstrual Cyclicity for Predicting Reproductive Toxicity

Advanced Science, EarlyView.
We present a dual‐organ, biomarker‐integrated ovaryendometrium organ‐on‐a‐chip that recapitulates 3D tissue complexity, menstrual cycle dynamics, and hormonal crosstalk. This platform enables real‐time, cell‐typespecific fluorescent readouts of reproductive toxicity using ANGPTL4 and SERPINB2 as early‐response reporters.
Soo‐Rim Kim, Eun‐kyung Min, Choon‐Mi Lee, Chan Hum Park, Byung‐Chul Oh, YunJae Jung, In‐Sun Hong   +6 more
wiley   +1 more source

ETV1 Drives CD4+ T Cell‐Mediated Intestinal Inflammation in Inflammatory Bowel Disease Through Amino Acid Transporter Slc7a5

Advanced Science, EarlyView.
This study identifies the transcription factor ETV1 as a key driver of CD4⁺ T cell‐mediated intestinal inflammation in inflammatory bowel disease (IBD). ETV1 promotes CD4⁺ T cell activation, proliferation, and Th17 differentiation by activating the amino acid transporter SLC7A5, fueling metabolic reprogramming.
Yan Shi, Song Wang, Yuqing Yan, Wei Chen, Yingying Cao, Dafan Chen, Wei Chen, Caiyun Ma, Xinjian Wan   +8 more
wiley   +1 more source

The Association of Polymyalgia Rheumatica and Giant Cell Arteritis With COVID-19 Vaccination: A Systematic Review. [PDF]

Clin Med Insights Arthritis Musculoskelet Disord
Shahid F, Farooq H, Abeer H, Mahmood GM, Sheikh H, Ameer MZ, Fatima L, Ameer F, Amjad Z, Ahmad TZ, Rehman G, Rehman AU.   +11 more
europepmc   +1 more source

Adipose‐Derived Mesenchymal Stem Cell Secretome for Post‐Steroid Hypopigmentation and Skin Atrophy: A Case Report [PDF]

Shannaz Nadia Yusharyahya, Valdi Ven Japranata, Endi Novianto   +2 more
openalex   +1 more source