Results 131 to 140 of about 336,142 (217)

Respiratory effects of off label anakinra in critically ill neonates: a 15-patient observational cohort study. [PDF]

Front Pediatr
De Rose DU, Cesaroni GM, Campi F, Maddaloni C, Ronci S, Caoci S, Capolupo I, Dotta A.   +7 more
europepmc   +1 more source

Spatially Organized Human Ovarian Spheroids Instruct Endometrial Morphogenesis

Advanced Science, EarlyView.
A spatially organized human follicle‐like spheroid (SPHEGaT) composed of granulosa cells (GCs) and stromal‐derived theca‐like cells (TLCs) establishes sustained steroidogenesis in vitro. When co‐cultured with human endometrial organoids (EMOs), estradiol (E2) and progesterone (P4) exchange induces secretory/progesterone‐responsive differentiation ...
Maria João Sousa, Silke De Vriendt, Lixian Liu, Thalles Fernando Rocha Ruiz, Hugo Vankelecom, Christiani Andrade Amorim   +5 more
wiley   +1 more source

Role of next-generation sequencing in epidemic retinitis. [PDF]

Indian J Ophthalmol
Kawali A, Rashmi B, Mishra SB, Mahendradas P.   +3 more
europepmc   +1 more source

Ubiquitination of ACSL4 by Parkin Suppresses Ferroptosis and Rescues Glucocorticoid‐Induced Bone Loss

Advanced Science, EarlyView.
GCs reduce Parkin, leading to ACSL4 accumulation and PUFA‐phospholipid‐driven ferroptosis in BMSCs, which impairs osteogenesis and promotes adipogenesis, causing GIOP. Parkin restoration (via OE‐Parkin or Parkin‐LNP@DSS6) ubiquitinates and degrades ACSL4, inhibiting ferroptosis, rescuing bone formation, and rescues GIOP bone loss.
Li‐jiang Han, Jian‐sen Miao, Yi‐feng Shi, Yi‐ting Tu, Yu‐zhe Lin, Lin‐Jie Chen, Bing‐hao Lin, Hua‐lin Li, Xuan‐qi Zheng, Hong‐qiang Wu, Hai‐xiao Liu, Lei Yang, Ai‐min Wu, Zhen Lin, Jian Xiao, Gang Zheng, Chen Jin   +16 more
wiley   +1 more source

Systemic steroid treatment of grade I acute GVHD increases steroid-refractory GVHD and NRM. [PDF]

Blood Immunol Cell Ther
Akahoshi Y, Katsivelos N, Louloudis IE, Weber D, Ayuk F, Hogan WJ, Chen YB, Etra AM, Aguayo-Hiraldo P, Chanswangphuwana C, Choe HK, Hexner EO, Kitko CL, Al Malki MM, Merli P, Olson TS, Qayed M, Vasova I, Wölfl M, Baez J, Eng G, Gleich S, Morales G, Spyrou N, Young R, Diniz M, Nakamura R, Levine JE, Ferrara JLM.   +28 more
europepmc   +1 more source

CA9‐Targeted PET Imaging for Noninvasive Discrimination of Clear Cell Renal Cell Carcinoma and Associated Tumor Biological Features

Advanced Science, EarlyView.
CA9‐targeted PET imaging could be a noninvasive approach to characterize clear cell renal cell carcinoma and associated tumor biology. PET uptake correlates with tumor CA9 expression and is linked to angiogenic activity, immune remodeling, and metabolic reprogramming.
Kailei Chen, Sixuan Cheng, Jian Shi, Ruijie Liu, Yilong Wu, Xin Zheng, Xinlun Song, Yunxuan Zhang, Lei Liu, Zhihao Wei, Qi Wang, Xinwei Li, Zirui Dong, Yuenan Liu, Hongmei Yang, Xiaoli Lan, Chunxia Qin, Dawei Jiang, Keshan Wang, Xiaoping Zhang   +19 more
wiley   +1 more source

Neonatal reference intervals for salivary steroids: focus on prematurity, stressful events and perinatal betamethasone. [PDF]

Front Pediatr
Zykova SN, Plaksienko A, Solevåg AL, Brigtsen AK, Michelsen TM, Sørbye IK, Bentsen MHL, Bakke LH, Elboth JE, Berg JP, Dahl SR, Thorsby PM.   +11 more
europepmc   +1 more source

Molecular Dynamics‐Guided Sterol Engineering of mRNA‐Lipid Nanoparticles Reprograms Biodistribution and Enhances Spleen‐Selective Immunity

Advanced Science, EarlyView.
Sterol engineering enables precise control of mRNA lipid nanoparticles by tuning membrane organization. Replacing cholesterol with bile acid‐derived sterols redirects protein expression from the liver to the spleen. Notably, CA‐20 LNP enhances antigen‐specific immune responses while exhibiting a favorable safety profile, highlighting sterols as a ...
Sanghyuk Jeon, Seo‐Hyeon Bae, Jungyong Ji, Jisun Lee, Hosam Choi, Min‐Ho Kang, Sang‐In Park, Hyemin Kim, Nakyung Lee, Hajin Lee, Seonghoon Kim, Jungmin Kim, Subin Yoon, Seonghyun Lee, Seongje Cho, Dahyeon Ha, Ayoung Oh, Sohee Jo, Huijeong Choi, Yeeun Lee, Sowon Lee, Hyo‐Jung Park, Gitak Nam, Jisu Shin, Yujin Kang, Wonpil Im, Kiyoun Lee, Jae‐Hwan Nam   +27 more
wiley   +1 more source

Sarcoma de Kaposi por dosis altas de esteroides

Medisan
Se describe el caso clínico de una paciente de 42 años de edad, quien necesitó tratamiento reiterado con prednisona y a partir de entonces comenzó a presentar lesiones cutáneas en ambas piernas.
Lilia E Chércoles Cazate, Migdonia Contreras Despaigne, Juana Adela Fong Estrada   +2 more
doaj  

Effects of Topical Steroids on Postoperative Pain in Patients Undergoing Stand-Alone Lateral Lumbar Interbody Fusion. [PDF]

Cureus
Tani S, Dalton DM, Hunker JJ, Zhu J, Shue J, Fantini GA, Lebl DR, Cammisa FP, Girardi FP, Hughes AP, Sokunbi G, Sama AA, Zelenty WD.   +12 more
europepmc   +1 more source