Results 171 to 180 of about 752,763 (369)

Targeting Adipose Tissue Function Protects Against Heart Failure with Preserved Ejection Fraction

open access: yesAdvanced Science, EarlyView.
This study explores the role adipose tissue (AT) phenotypes have in determining cardiovascular outcomes in an obesity‐related heart failure with preserved ejection fraction (HFpEF) model. Pharmacological induction of thermogenesis promoted resilience to HFpEF‐induced remodeling of AT and conferred cardioprotection. Surgical and genetic models confirmed
Jordan Jousma   +11 more
wiley   +1 more source

Spartan Daily, April 3, 2014 [PDF]

open access: yes, 2014
Volume 142, Issue 25https://scholarworks.sjsu.edu/spartandaily/1485/thumbnail ...
San Jose State University, School of Journalism and Mass Communications
core   +1 more source

Targeted Inhibition of CD74+ Macrophages by Luteolin via CEBPB/P65 Signaling Ameliorates Osteoarthritis Progression

open access: yesAdvanced Science, EarlyView.
This study identifies CD74⁺ macrophages as key drivers of synovial inflammation in osteoarthritis (OA). The flavonoid luteolin is predicted to inhibit this pathway by blocking Nuclear Factor Kappa‐light‐chain‐enhancer of Activated B cells (NF‐κB) signaling. To enhance delivery, a targeted nanoplatform (MDSPL) is developed.
Rui Peng   +15 more
wiley   +1 more source

Sex steroids do not affect muscle weight, oxidative metabolism or cytosolic androgen reception binding of functionally overloaded rat Plantaris muscles [PDF]

open access: yes
The effects of sex steroids on muscle weight and oxidative capacity of rat planaris muscles subjected to functional overload by removal of synergistic muscles were investigated.
Max, S. R., Rance, N.
core   +1 more source

Steroid receptor coactivator‐2 drives epithelial reprogramming that enables murine embryo implantation

open access: hybrid, 2023
Vineet K. Maurya   +7 more
openalex   +1 more source

Profiles of Steroid Hormones on Follicular and Luteal Phase in Saanen Etawah Crossbred (SAPERA) Does [PDF]

open access: hybrid, 2022
Seraphina Kumala   +3 more
openalex   +1 more source

TREM2 Drives Neutrophil Extracellular Traps‐Induced Dendritic Cell Maturation and Contributes to Lupus Progression

open access: yesAdvanced Science, EarlyView.
TREM2 recognizes NETs‐derived MPO to promote DC maturation and antigen presentation, thereby exacerbating the autoimmune response in SLE. Mechanistically, TREM2 activation triggers the DAP12/SYK/ERK cascade and enhances NETs internalization by DCs, which in turn activates the cGAS/STING signaling pathway.
Jingxian Shu   +7 more
wiley   +1 more source

Severe Pulmonary Involvement in Leptospirosis : Alternate antibiotics and systemic steroids

open access: yesSultan Qaboos University Medical Journal, 2013
Pulmonary complications in leptospirosis, though common, are often unrecognized in a non-endemic area. We report here a patient with leptospirosis and severe pulmonary involvement who was treated with meropenem (1 g every 8 hours), moxifloxacin (400 mg ...
Jayakrishnan B   +6 more
doaj  

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