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Steroids

Current Opinion in Critical Care, 2002
Corticosteroids are considered to be essential stress hormones. They are secreted together with adrenocorticotropic hormone (ACTH) in response to the pulsatile secretion of corticotropin-releasing hormone from the paraventricular nucleus of the hypothalamus.
Maggy, Riad   +3 more
openaire   +2 more sources

Heterocyclic steroids. Steroidal pyrimidines

Experientia, 1963
Die erste Synthese eines Steroid-Analogen, in welchem Ring A zu einem Pyrimidin umgewandelt wurde, wird beschrieben. Die wichtigste Zwischenstufe 4b wurde durch Abbau von 19-nor-Testosteron gewonnen. Kondensation von 4b mit Thioharnstoff fuhrte zu 17β-Acetoxy-2,4-diazaestr-4-en-1-on-3-thion (5).
E, CASPI, D M, PIATAK
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STEROIDS AND STEROID-LIKE COMPOUNDS

Clinics in Sports Medicine, 1999
Athletes have been searching for an "edge" in competition as long as there has been a reward for success. Anabolic-androgenic steroids have been the most popular of these ergogenic aids when winning is the only goal. The authors present a concise review of these substances, their prevalence, efficacy, adverse effects, and legality.
J G, Blue, J A, Lombardo
openaire   +2 more sources

Somatomedins and Steroids

Hormone Research, 2008
Somatomedin levels measured by radioreceptor assay, competitive protein-binding assay or radioimmunoassay are normal in hypercortisolism; the decrease of somatomedin activity consistently found in this condition is due to an increase in circulating somatomedin inhibitors resulting in an inhibition of somatomedin action. Progestagens could possibly have
Caufriez, Anne, Copinschi, Georges
openaire   +3 more sources

Steroids and hypertension

The Journal of Steroid Biochemistry and Molecular Biology, 1991
Primary aldosteronism is the principal disorder of zona glomerulosa and a number of subsets have been identified: unilateral adenoma; bilateral micro- or macro-nodular hyperplasia (idiopathic aldosteronism); primary hyperplasia and aldosterone-producing carcinoma either adrenal or ectopic. The diagnostic criteria for a correct differential diagnosis of
MANTERO, FRANCO   +8 more
openaire   +3 more sources

Steroids and Steroid-Sparing Agents in Asthma

New England Journal of Medicine, 1988
Asthma is a disease characterized by an increase in airway reactivity together with a propensity for the airways to constrict in response to a variety of stimuli.1 The cumulative prevalence of this disorder in America is estimated to be between 5 and 7 percent.2 Prompt, regular, and aggressive therapy with inhaled beta-adrenergic agents, theophylline ...
G R, Cott, R M, Cherniack
openaire   +2 more sources

Steroid derivatives as inhibitors of steroid sulfatase

The Journal of Steroid Biochemistry and Molecular Biology, 2013
Sulfated steroids function as a storage reservoir of biologically active steroid hormones. The sulfated steroids themselves are biologically inactive and only become active in vivo when they are converted into their desulfated (unconjugated) form by the enzyme steroid sulfatase (STS).
Yaser A, Mostafa, Scott D, Taylor
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Steroid structure and steroid activity

British Journal of Dermatology, 1976
The diverse biological effects associated with naturally occurring steroids are reviewed, with particular reference to the effect upon biological activity of changes in chemical structure. The motives for synthetic modification of the natural products are discussed and are illustrated by reference to the development of systemic and topical anti ...
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