Results 261 to 270 of about 398,765 (315)
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Non-Steroidal Steroid Receptor Modulators
Current Medicinal Chemistry, 2005The last ten years much attention has been focused on the finding of non-steroidal ligands for steroidal nuclear receptors for reasons such as diminishing cross-reactivity to eliminate side effect profiles, changing physicochemical properties which might cause different tissue distribution profiles and altering binding modes which influence the binding
Rogier C, Buijsman +4 more
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Steroidal and Non-Steroidal Inhibitors of Steroid Sα-Reductase
Current Medicinal Chemistry, 1995Abstract: A good deal of interest exists in developing inhibitors of steroid Sa-reductase (SR) as a therapy for pharmacological disorders associated with elevated levels of dihydrotestosterone (DHT), the product of SR action on testosterone (T). The recent identification of two isoforms of SR (Types 1 and 2) has intensified this effort to include the ...
A.D. Abell, B.R. Henderson
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Steroids, steroid precursors, and neuroactive steroids in critically ill equine neonates
The Veterinary Journal, 2017Hypothalamic-pituitary-adrenal axis (HPAA) dysfunction has been associated with sepsis and mortality in foals. Most studies have focused on cortisol, while other steroids have not been investigated. The objectives of this study were to characterise the adrenal steroid and steroid precursor response to disease and to determine their association with the
K A, Dembek +7 more
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Journal of Steroid Biochemistry, 1975
Abstract The unopposed continuous administration of biologically active estrogenic materials produces a wide variety of cancers in experimental animals. Most of these cancers occur in the target tissues for estrogenic activity and appear to be characteristic of the animal rather than the estrogens.
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Abstract The unopposed continuous administration of biologically active estrogenic materials produces a wide variety of cancers in experimental animals. Most of these cancers occur in the target tissues for estrogenic activity and appear to be characteristic of the animal rather than the estrogens.
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The Laryngoscope, 1989
AbstractA prospective double‐blind randomized pilot study was performed to test the benefits of steroids versus placebo in controlling edema and ecchymosis in rhinoplasty within the immediate postoperative period. Thirty consecutive patients who underwent rhinoplasty with osteotomies were entered into the study.
W S, Griffies +4 more
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AbstractA prospective double‐blind randomized pilot study was performed to test the benefits of steroids versus placebo in controlling edema and ecchymosis in rhinoplasty within the immediate postoperative period. Thirty consecutive patients who underwent rhinoplasty with osteotomies were entered into the study.
W S, Griffies +4 more
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Steroid-Induced, Steroid-Producing, and Steroid-Responsive Tumors
1976As an introduction to the chapters to follow, this report will aim to present certain hopefully provocative observations on the nature of steroid-related tumors in man and animals.
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Steroids, neuroactive steroids and neurosteroids in psychopathology
Progress in Neuro-Psychopharmacology and Biological Psychiatry, 2005The term "neurosteroid" (NS) was introduced by Baulieu in 1981 to name a steroid hormone, dehydroepiandrosterone sulfate (DHEAS), that was found at high levels in the brain long after gonadectomy and adrenalectomy, and shown later to be synthetized by the brain.
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Seminars in Fetal and Neonatal Medicine, 2019
Steroids are complex lipophilic molecules that have many actions in the body to regulate cellular, tissue and organ functions across the life-span. Steroid hormones such as cortisol, aldosterone, estradiol and testosterone are synthesised from cholesterol in specialised endocrine cells in the adrenal gland, ovary and testis, and released into the ...
Timothy J, Cole +2 more
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Steroids are complex lipophilic molecules that have many actions in the body to regulate cellular, tissue and organ functions across the life-span. Steroid hormones such as cortisol, aldosterone, estradiol and testosterone are synthesised from cholesterol in specialised endocrine cells in the adrenal gland, ovary and testis, and released into the ...
Timothy J, Cole +2 more
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Profiling steroid hormones and urinary steroids
Journal of Chromatography B: Biomedical Sciences and Applications, 1986This paper reviews techniques utilized in the profiling of steroids in body fluids and tissues. Methods for profiling plasma unconjugated steroids and urinary steroid metabolites are focused on. Concentrations or levels of excretion of a variety of steroids have been documented and reviewed. The importance of profiling techniques in the study of normal
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2016
Chronic rhinosinusitis with nasal polyps (CRSwNP) is an inflammatory condition with heterogeneous pathophysiology. A cornerstone of the management of this condition is the use of anti-inflammatory agents. Corticosteroids are very effective and the most commonly used, but other drugs with immunodulatory activity such as anti-IL5, doxycycline (Th2), and ...
Gretchen M, Oakley, Richard J, Harvey
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Chronic rhinosinusitis with nasal polyps (CRSwNP) is an inflammatory condition with heterogeneous pathophysiology. A cornerstone of the management of this condition is the use of anti-inflammatory agents. Corticosteroids are very effective and the most commonly used, but other drugs with immunodulatory activity such as anti-IL5, doxycycline (Th2), and ...
Gretchen M, Oakley, Richard J, Harvey
openaire +2 more sources