Divergent Evolution of Progesterone and Mineralocorticoid Receptors in Terrestrial Vertebrates and Fish Influences Endocrine Disruption [PDF]
arXiv, 2021 There is much concern about disruption of endocrine physiology regulated by steroid hormones in humans, other terrestrial vertebrates and fish by industrial chemicals, such as bisphenol A, and pesticides, such as DDT. These endocrine-disrupting chemicals influence steroid-mediated physiology in humans and other vertebrates by competing with steroids ...
arxiv
Interleukin-2 receptor antagonists for pediatric liver transplant recipients: A systematic review and meta-analysis of controlled studies [PDF]
Pediatric Transplantation, 18(8):839-850, 2014, 2014 Interleukin-2 receptor antagonists (IL-2RA) are frequently used as induction therapy in liver transplant recipients to decrease the risk of acute rejection while allowing the reduction of concomitant immunosuppression. The exact association with the use of IL-2RA however is uncertain.
arxiv +1 more source
Reduced steroid activation of elephant shark glucocorticoid and mineralocorticoid receptors after inserting four amino acids from the DNA-binding domain of lamprey corticoid receptor-1 [PDF]
arXiv, 2023 Atlantic sea lamprey contains two corticoid receptors (CRs), CR1 and CR2, that are identical except for a four amino acid insert (Thr-Arg-Gln-Gly) in the CR1 DNA-binding domain (DBD). Steroids are stronger transcriptional activators of CR2 than of CR1 suggesting that the insert reduces the transcriptional response of lamprey CR1 to steroids. The DBD in
arxiv
Diosgenin-3,6-dione: second polymorph in space group P212121
IUCrData, 2020 The title steroid, [(25R)-spirost-4-en-3,6-dione, C27H38O4], is obtained by oxidation of diosgenin, using the Jones reagent (CrO3/H2SO4). The crystal structure was previously reported in space group P212121, but nonetheless with the wrong absolute ...
Gabriel Guerrero-Luna +3 more
doaj +1 more source
Evaluation of Intraocular Pressure Changes with Topical Dexamethasone 0.1%, Prednisolone 1% and Difluprednate 0.05% Postcataract Surgery- A Randomised Clinical Trial [PDF]
Journal of Clinical and Diagnostic Research, 2021 Introduction: Topical corticosteroids are most commonly used for the control of postoperative inflammation after cataract surgery. Topical steroids may cause increase in Intraocular Pressure (IOP) which, if left untreated may lead to progressive ...
Sachit Mahajan +4 more
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A multivariate Bayesian learning approach for improved detection of doping in athletes using urinary steroid profiles [PDF]
arXiv, 2023 Biomarker analysis of athletes' urinary steroid profiles is crucial for the success of anti-doping efforts. Current statistical analysis methods generate personalised limits for each athlete based on univariate modelling of longitudinal biomarker values from the urinary steroid profile.
arxiv
Medwave, 2020 Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) has rapidly spread throughout the world causing significant mortality in high risk patients with severe manifestations.
José A Gonzales-Zamora +2 more
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Frontiers in NeurologyBackgroundNewly diagnosed people with multiple sclerosis frequently report fatigue, pain, depression and anxiety. Preventative programmes may be beneficial, but there is limited evidence of their effectiveness, especially long-term follow-up.MethodsThe ...
Natália Hrušková +10 more
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Indian Journal of Dermatology, 2013 Background: Oral minipulse (OMP) therapy with methylprednisolone is presently one of the most common oral treatments used for progressive vitiligo in children.
Imran Majid, Saher Imran
doaj +1 more source
Ocular and Systemic Complications of COVID-19: Impact on Patients and Healthcare
Clinical Ophthalmology, 2022 Ella H Leung,1 Jason Fan,2 Harry W Flynn Jr,2 Thomas A Albini2 1Georgia Retina, Atlanta, GA, USA; 2Bascom Palmer Eye Institute/University of Miami, Miami, FL, USACorrespondence: Ella H LeungGeorgia Retina, 833 Campbell Hill St NW, Suite 300, Marietta, GA,
Leung EH, Fan J, Flynn Jr HW, Albini TA
doaj