Results 81 to 90 of about 438,779 (309)

Steroids: GC Analysis [PDF]

, 2009
Insufficient volatility and thermal stability are the biggest challenges in the application of gas chromatography for the analysis of steroids. The development of gas chromatography (GC) methods for steroids analysis should take in consideration thermal ...
Mochammad Yuwono, Gunawan Indrayanto, Suciati   +2 more
core   +1 more source

Single-cell RNA sequencing reveals T helper cells synthesizing steroids de novo to contribute to immune homeostasis [PDF]

, 2014
T helper 2 (Th2) cells regulate helminth infections, allergic disorders, tumor immunity, and pregnancy by secreting various cytokines. It is likely that there are undiscovered Th2 signaling molecules.
Xiuwei Zhang, Sarah A. Teichmann, Zhang, Xiuwei, Dingler, Felix A., Felix A. Dingler, Teichmann, Sarah A., Valentina Proserpio, Berthold Göttgens, Dingler, Felix A, Kolodziejczyk, Aleksandra A, Teichmann, Sarah A, Proserpio, V, Taylor, Angela E., Hebenstreit, Daniel, Taylor, Angela E; id_orcid, Proserpio, Valentina, Haim-Vilmovsky, Liora, McKenzie, Andrew N J, Liora Haim-Vilmovsky, Göttgens, Berthold, Andrew N.J. McKenzie, Arlt, Wiebke, Angela E. Taylor, Daniel Hebenstreit, Kolodziejczyk, Aleksandra A., Aleksandra A. Kolodziejczyk, Wiebke Arlt, Victoria Moignard, Moignard, Victoria, McKenzie, Andrew N. J., Bidesh Mahata, Mahata, Bidesh, McKenzie, Andrew NJ, Goettgens, Berthold, Taylor, Angela E   +34 more
core   +1 more source

Diffuse MRI Edema Predicts Relapse in Cerebral Amyloid Angiopathy–Related Inflammation

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective To identify MRI predictors of relapse and quantify relapse and mortality risk in cerebral amyloid angiopathy–related inflammation (CAA‐RI). A secondary objective was to assess the association between mycophenolate mofetil use and relapse risk. Methods We performed a retrospective cohort study of 36 patients with CAA‐RI treated at the
G. Abbas Kharal, Gowtham Yerneni, Kim J. Griffin, Nicolas Thompson, Ken Uchino, Irene Katzan, Dolora Wisco, Abeer Farrag, Jayashree Sundarajan, Andrew Russman, M. Shazam Hussain   +10 more
wiley   +1 more source

Use of Immune Modulating Agents to Regulate Hyperinflammation in Severe COVID 19: Assessment of Tocilizumab Use in Combination with Steroids

Journal of Research in Pharmacy Practice
Objective: In severe cases, COVID-19 can lead to a hyperinflammatory state, resulting in devastating outcomes. Immune modulation using steroids or other immune modulators can regulate the intensity of the inflammatory response; however, this theory has ...
Somayeh Sadeghi, Zohre Naderi, Nima Arezoomandi, Mozhdeh Saghaei, Fereshteh Tavakoli, Mahsa Hajizadeh   +5 more
doaj   +1 more source

New A-nor steroids and their antifouling activity from the Chinese marine sponge Acanthella cavernosa

, 2008
National Hi-Tech Development Project (863 project) [2006AA09Z446, 2006DFA31100, 2006AA09Z405]; NSFC [30672607, 30600053, 40176038, 30171106]; International Cooperation Projects of BMBF-MOSTA chemical examination of the Chinese sponge Acanthella cavernosa
邱彦, Qiu, Yan, Deng, Zhi Wei, Lin, Wen Han, Xu, Minjuan, Li, Qingshan   +5 more
core  

Utility of the APE2 Score as a Diagnostic Tool for Autoimmune Encephalitis

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective To retrospectively evaluate the diagnostic performance of the Antibody Prevalence in Epilepsy and Encephalopathy (APE2) score relative to clinician‐adjudicated autoimmune encephalitis (AE) and the Graus criteria in a tertiary neuroimmunology referral cohort, including antibody‐negative AE.
Bijoya Basu, Sophia F. Damman, Samhitha M. Rai, Hesham Abboud   +3 more
wiley   +1 more source

Glucocorticoid receptor activation by long acting steroids and its modification by inflammation [PDF]

, 2007
s: Glucocorticoids have an effective anti-inflammatory, anti-proliferative and immunomodulatory activity. Therefore this class of drugs is used worldwide for the treatment of inflammatory diseases and to prevent rejection following organ transplantation.
Yang, Jing-Qing
core   +1 more source

Early Clinical and Cerebrospinal Fluid Predictors of 1‐Year Recurrence in Autoimmune GFAP Astrocytopathy

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Autoimmune glial fibrillary acidic protein astrocytopathy (GFAP‐A) is an inflammatory central nervous system disorder with variable outcomes. Relapse occurs in a subset of patients, but early predictors remain unclear. We aimed to identify admission‐available features associated with 1‐year recurrence and develop an interpretable ...
Qingting Hong, Yuping Xiao, Yuhan Wu, Ziyuan Huang, Weishan Liang, Li Xiao, Yaqing Shu, Tingting Lu, Yanyu Chang, Wei Qiu, Yuge Wang   +10 more
wiley   +1 more source

Effectiveness of glucocorticoids in preventing esophageal stricture and predictors of stricture after esophageal ESD: 5 years of experience in a single medical center

Frontiers in Medicine
BackgroundEsophageal stricture is one of the major complications after endoscopic submucosal dissection (ESD) of the esophagus. However, even with steroid prophylaxis, stenosis still occurs in up to 45% of patients. Accordingly, the aim of this study was
Qingxia Wang, Yuan Ding, Qiliu Qian, Yinnan Zhu, Ruihua Shi   +4 more
doaj   +1 more source

Copine‐4 Paraneoplastic Autoimmune Encephalitis

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT We characterize copine‐4 (CPNE4)‐IgG and report clinical associations. Among 844 samples with unclassified neural IgGs identified by mouse‐brain indirect immunofluorescence assay over 2 years, 5 samples (serum, 3; CSF, 2) from 3 patients produced a distinctive cerebrum‐restricted synaptic pattern.
Mimi S. Fang, Amy Ml Quek, Clement Yong, Amir Adeli, Gabrielle N. Conway, Connie E. Lesnick, Diana Anissian, Divyanshu Dubey, John R. Mills, Sean J. Pittock, Anastasia Zekeridou, Michael Gilligan, Andrew McKeon   +12 more
wiley   +1 more source