Results 81 to 90 of about 429,473 (311)

Effects of anabolic androgenic steroids on chylomicron metabolism

, 2013
Objective: To evaluate the effects of anabolic androgenic steroids (AAS) on chylomicron metabolism. Methods: An artificial lipid emulsion labeled with radioactive cholesteryl ester (CE) and triglycerides (TG) mimicking chylomicrons was intravenously ...
Vinagre, Carmen G. C., Alves, Maria-Janieire N. N., Negrão, Carlos Eduardo, Morikawa, Aleksandra T., Silva, Jeferson L. da, Maranhão, Raul C.   +5 more
core   +1 more source

Early Clinical and Cerebrospinal Fluid Predictors of 1‐Year Recurrence in Autoimmune GFAP Astrocytopathy

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Autoimmune glial fibrillary acidic protein astrocytopathy (GFAP‐A) is an inflammatory central nervous system disorder with variable outcomes. Relapse occurs in a subset of patients, but early predictors remain unclear. We aimed to identify admission‐available features associated with 1‐year recurrence and develop an interpretable ...
Qingting Hong, Yuping Xiao, Yuhan Wu, Ziyuan Huang, Weishan Liang, Li Xiao, Yaqing Shu, Tingting Lu, Yanyu Chang, Wei Qiu, Yuge Wang   +10 more
wiley   +1 more source

Prevalence of Systemic Lupus Erythematosus in Australia, 2010–2022: A Population‐Based Study Using Linked National Administrative Health Data

Arthritis Care &Research, EarlyView.
Objective Systemic lupus erythematosus (SLE) is a heterogenous inflammatory condition with widely varying global prevalence estimates. The frequency of SLE in the general population of Australia has been reported to be notably lower than contemporary estimates in countries such as the United States or United Kingdom, at 19 to 39 per 100,000 as opposed ...
Lucinda Roper, Rachel Black, Joanna Tieu, Winnie Chen, Matthew Parker, Catherine Hill, Natasha Nassar, Mandana Nikpour   +7 more
wiley   +1 more source

A versatile synthesis of 17-heteroaryl androstenes via palladium-mediated Suzuki cross-coupling with heteroaryl boronic acids

, 2006
Suzuki coupling of 17-iodoandrosta-5,16-dien-3 beta-ol (1) and 17-iodoandrosta-4,16-dien-3-one (2) with nine heteroaryl boronic acids (mainly 2- or 3-furanyl, thienyl, benzofuranyl and benzothienyl boronic acid derivatives) were carried out under normal ...
Luo, Xuande, Yangzhi Ling, Brodie, A. M. H., Xiaofeng Liu, Jianping Chao, Xuande Luo, Ling, Yangzhi, Liu, Xiaofeng, A.M.H. Brodie, Chao, Jianping   +9 more
core   +1 more source

Regulation of 3β-Hydroxysteroid Dehydrogenase/∆5-∆4 Isomerase: A Review [PDF]

, 2013
This review focuses on the expression and regulation of 3β-hydroxysteroi ddehydrogenase/Δ5-Δ4 isomerase (3β-HSD), with emphasis on the porcine version. 3β-HSD is often associated with steroidogenesis, but its function in the metabolism of both steroids ...
Martin Krøyer Rasmussen, Galia Zamaratskaia, Bo Ekstrand, Bo Ekstr, Martin Rasmussen, Ekstrand, Bo, Zamaratskaia, Galia, Rasmussen, Martin Krøyer, Sveriges lantbruksuniversitet., Zamaratskaia, Galia,   +9 more
core   +1 more source

Clinical Significance of Therapeutic Drug Level Monitoring for Mycophenolate in Patients With Extrarenal Systemic Lupus Erythematosus—A Systematic Review and Meta‐Analysis

Arthritis Care &Research, EarlyView.
Objective Clinical response to mycophenolic acid (MPA) is highly heterogeneous; thus, therapeutic drug level monitoring (TDM) may help improve treatment efficacy. This systematic review and meta‐analysis examined therapeutic ranges for MPA levels associated with better outcomes and safety in patients with systemic lupus erythematosus (SLE ...
Zahraa Qamhieh, Dalia Sriwi, Callie Saric, Tripti Singh, Christie M. Bartels, Shivani Garg   +5 more
wiley   +1 more source

Building a Framework for Sexual and Reproductive Health Care in the Rheumatology Context: Content and Approaches

Arthritis Care &Research, EarlyView.
People with systemic autoimmune and rheumatic diseases (SARDs) are at higher risk than the general population of experiencing adverse pregnancy and perinatal outcomes such as preeclampsia, intrauterine growth restriction, and maternal and/or fetal death.
Mehret Birru Talabi, Sonya Borrero
wiley   +1 more source

Unusual Presentation of Cryptogenic Organising Pneumonia as a Focal Lung Mass: A Case Report and Literature Review

Respirology Case Reports
Organising pneumonia (OP) is a distinct pathological pattern characterised by the presence of granulation tissue buds composed of fibroblasts and myofibroblasts embedded in a loose connective tissue matrix within the distal pulmonary airspaces.
Boon Hau Ng, Hsueh Jing Low, Nik Nuratiqah Nik Abeed, Nor Safiqah Sharil, Rose Azzlinda Osman, Andrea Yu‐Lin Ban   +5 more
doaj   +1 more source

Concomitant use of corticosteroids and immune checkpoint inhibitors in patients with solid neoplasms: A real-world experience from a tertiary cancer center

Cancer Research, Statistics, and Treatment, 2019
Introduction: Checkpoint inhibitors (CPIs) are rapidly becoming the standard of care in solid tumors for multiple indications. Steroids due to their immunosuppressive nature might decrease the efficacy of these agents.
Akhil Kapoor, Vanita Noronha, Vijay M Patil, Amit Joshi, Nandini Menon, George Abraham, Vikas Talreja, Hollis D′Souza, Kumar Prabhash   +8 more
doaj   +1 more source

Changing minds: Understanding the use of oral steroids in acute asthma

Asthma is a heterogenous disease with a substantial global burden. Asthma attacks are treated based on symptoms alone with oral steroids despite some attacks displaying little evidence of type-2 inflammation.
Howell, Imran
core   +1 more source