Results 91 to 100 of about 19,805 (217)

Exposure of Aspergillus fumigatus to Klebsiella pneumoniae Culture Filtrate Inhibits Growth and Stimulates Gliotoxin Production

open access: yesJournal of Fungi, 2023
Aspergillus fumigatus is an opportunistic fungal pathogen capable of inducing chronic and acute infection in susceptible patients. A. fumigatus interacts with numerous bacteria that compose the microbiota of the lung, including Pseudomonas aeruginosa and
Aaron Curtis   +2 more
doaj   +1 more source

The Nutritional Composition and Multi‐Omics Analysis of Raw Milk From Normande and Holstein Cows

open access: yesFood Frontiers, EarlyView.
Normande milk is characterized by high protein and fat content, whereas Holstein milk is distinguished by its high milk yield. However, few studies have reported on their compositional differences. Thus, we used physicochemical and multi‐omics techniques to investigate the compositional differences between Normande and Holstein raw milks. ABSTRACT Milk
Yuanyuan Li   +9 more
wiley   +1 more source

Expression of fatty acid and lipid biosynthetic genes in developing endosperm of Jatropha curcas [PDF]

open access: yes, 2012
BACKGROUND: Temporal and spatial expression of fatty acid and lipid biosynthetic genes are associated with the accumulation of storage lipids in the seeds of oil plants.
Chengxin Yi   +5 more
core   +1 more source

DNA methyltransferase 1 deficiency improves macrophage motility and wound healing by ameliorating cholesterol accumulation

open access: yesnpj Regenerative Medicine, 2023
Healing of the cutaneous wound requires macrophage recruitment at the sites of injury, where chemotactic migration of macrophages toward the wound is regulated by local inflammation. Recent studies suggest a positive contribution of DNA methyltransferase
Chuanrong Zhao   +13 more
doaj   +1 more source

Coordinated regulation of hepatic and adipose tissue transcriptomes by the oral administration of an amino acid mixture simulating the larval saliva of Vespa species [PDF]

open access: yes, 2016
Genes mapped on Fig. 3.
Akihito Yasuoka   +10 more
core   +4 more sources

Multiomics analyses reveal that PRMT5 regulates membrane transport and cholesterol synthesis in white adipocytes

open access: yesiMetaOmics, EarlyView.
Prmt5AKO downregulates genes related to fatty acid transport and triacylglycerol synthesis, while upregulating genes involved in glucose transport and cholesterol biogenesis. These changes cause alternation in lipid composition and metabolic phenotypes of Prmt5AKO mice. Abstract The adipose tissue (AT) is a main regulator of systemic energy homeostasis,
Xiyue Chen   +7 more
wiley   +1 more source

The effects of PCB126 on intra-hepatic mechanisms associated with non alcoholic fatty liver disease [PDF]

open access: yes, 2015
Background Non alcoholic fatty liver disease (NAFLD) results from alteration in lipid synthesis and elimination mechanisms such as very-low density lipoprotein (VLDL) production and de novo lipogenesis. Persistent organic pollutants (POPs)
Caroline Lefebvre   +2 more
core   +1 more source

The Contribution of Cholesterol and Squalene Synthase in Cancer: Molecular Mechanisms, Lipid Rafts and Therapeutic Approaches

open access: yesMedicinal Research Reviews, EarlyView.
ABSTRACT A plethora of cellular signaling pathways are dysregulated in cancer cells, promoting carcinogenesis and migration. Cholesterol has recently been linked to cancer by several subcellular mechanisms, especially by its involvement in the formation of lipid rafts, which promote oncogenic signaling and cancer cell invasion. Squalene synthase (SQS),
Danai Mavridi   +2 more
wiley   +1 more source

Genetic engineering and molecular characterization of yeast strain expressing hybrid human-yeast squalene synthase as a tool for anti-cholesterol drug assessment [PDF]

open access: yes, 2016
AIMS: The main objective of the study is molecular and biological characterization of the human-yeast hybrid squalene synthase (SQS), as a promising target for treatment of hypercholesterolaemia.
Burzynska, Beata   +12 more
core   +1 more source

A Mediterranean Diet‐Based Food Mix Ameliorates Diabetes‐ and Obesity‐Associated Liver Alterations Through Mitochondrial and Metabolic Reprogramming

open access: yesMolecular Nutrition &Food Research, EarlyView.
Metabolic syndrome (MetS)‐related conditions are key factors in liver damage. A Mediterranean lifestyle shows promise in managing MetS, though its mechanisms remain unclear. This study tested a lab‐designed food mix mimicking the 1960s Mediterranean Diet (MD) on obese and diabetic mice; it prevented hyperlipidemia and reduced oxidative liver damage ...
Giovanna Mercurio   +13 more
wiley   +1 more source

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