Results 121 to 130 of about 13,985 (173)

Adrenocortical Mitochondria-Associated Membranes: Isolation, Characterization, and Lipidoproteomic Response to Mitotane. [PDF]

J Endocr Soc
Krüger AF, Schmitz W, Lamer S, Triebig A, Maier T, Fuss CT, Angeli JPF, Schlosser A, Stigloher C, Fassnacht M, Weigand I, Kroiss M.   +11 more
europepmc   +1 more source

Temporal Dynamics of CNS Cholesterol Esters Correlate with Demyelination and Remyelination. [PDF]

ACS Chem Neurosci
De Silva Mohotti N, Williams JM, Binjawadagi R, Kobayashi H, Dedunupitiya D, Petersen JM, Garcia A, Hartley MD.   +7 more
europepmc   +1 more source

Lipid metabolism-related genes in gastric cancer: Exploring oncogenic pathways. [PDF]

World J Gastrointest Oncol
Amir M, Bakht D, Bokhari SFH, Yousaf R, Iqbal A, Nazir H, Waleed M, Naqvi MZ, Tahir M, Dost W.   +9 more
europepmc   +1 more source

SREBF2 enhances lipid metabolism and represses anti-tumor immune responses in cervical cancer by increasing ACAT2. [PDF]

Commun Biol
Zhang Y, Shao Y, Li X, Zhou D, Zhou J, Yan Q, Gao W, Yang L.   +7 more
europepmc   +1 more source

Maternal docosahexaenoic acid and eicosapentaenoic acid supplementation: effects and mechanisms on lipid metabolism in the offspring. [PDF]

Front Nutr
Shao C, Lin H, Yu J, Chen H, Ren Y, Ren J, Zeng Y, Wu Y, Zhang Q, Xiao X.   +9 more
europepmc   +1 more source

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Knockdown of sterol O-acyltransferase 1 (SOAT1) suppresses SCD1-mediated lipogenesis and cancer procession in prostate cancer.

Prostaglandins & Other Lipid Mediators, 2021
Prostate cancer (PCa) is one of the most fatal malignant tumors that occurs in the prostate epithelium, especially in older men, the mortality of which ranks sixth among all cancer-related deaths. It has been urgently needed to elucidate the pathogenesis
Yuan Liu, Yeqiang Wang, Sida Hao, Yong Qin, Yuye Wu   +4 more
semanticscholar   +3 more sources

Targeting sterol O-acyltransferase 1 rewires fatty acid metabolism and uncovers immune vulnerability in hepatocellular carcinoma.

Hepatology
BACKGROUND AND AIMS The development of hepatocellular carcinoma (HCC) is intricately linked to metabolic processes and immune evasion strategies. As an emerging metabolic vulnerability in HCC, detailed molecular mechanisms of Sterol O-Acyltransferase 1 ...
Huanhuan Ma, Vanilla Xin Zhang, Y. Tsui, J. Lee, Eva K. Lee, Jingyi Lu, Huan Deng, Fan-Hong Zeng, DanielWai-Hung Ho, C. Hui, Abdullah Husain, K. Sze, Irene Oi-Lin Ng   +12 more
semanticscholar   +2 more sources

Impact of the sterol O-acyltransferase gene (Cmare2) on morphology and stability of the mushroom Cordyceps militaris.

International Journal of Biological Macromolecules
Strain degeneration in mushroom cultivation can lead to significant commercial losses, yet the genetic factors remain elusive. This study identified the sterol O-acyltransferase gene, Cmare2, which is associated with colony sectorization in Cordyceps ...
MengQian Liu, Mengfei Zhang, Meiyu Huai, Fangxu Xu, Guoliang Meng, Fen Wang, Caihong Dong   +6 more
semanticscholar   +3 more sources

Abstract 5468: A pharmacological inhibition of sterol O-acyltransferase 1improves response to enzalutamide in prostate cancer

Cancer Research, 2022
Prostate cancer (PCa) growth is mediated by androgens via activation of androgen receptor (AR). Accordingly, androgen deprivation therapy (ADT) is the gold standard for the treatment of advanced PCa, but progression to castration-resistant PCa (CRPC ...
Sora Q. Kim, S. Utturkar, Nadia M Atallah, Kee-Hong Kim   +3 more
semanticscholar   +2 more sources

Callyspongiamides A and B, sterol O-acyltransferase inhibitors, from the Indonesian marine sponge Callyspongia sp.

Bioorganic & Medicinal Chemistry Letters, 2018
Callyspongiamides A (1) and B (2), two new sterol O-acyltransferase (SOAT) inhibitors, were isolated from the Indonesian marine sponge Callyspongia sp. together with a known congener, dysamide A (3).
M. M. Kapojos, D. B. Abdjul, H. Yamazaki, Taichi Ohshiro, H. Rotinsulu, D. Wewengkang, D. Sumilat, H. Tomoda, M. Namikoshi, R. Uchida   +9 more
semanticscholar   +3 more sources