Results 131 to 140 of about 14,545 (218)

TsR-0072 inhibits colorectal cancer progression through modulating lipid and vitamin D3 metabolic reprogramming and inactivating the Wnt/β-catenin signalling pathway

Annals of Medicine
Background tRNA-derived small RNAs (tsRNAs), newly developed non-coding RNAs with specialized biological features, are aberrantly expressed in the majority of malignancies.
Qianyi Qi, Bairong Chen, Jinran Wu, Jing Xu, Hongyi Bao, Kangfeng Jin, Lin Chen, Guang Zhu, Feng Wang   +8 more
doaj   +1 more source

Mboat7 down-regulation by hyper-insulinemia induces fat accumulation in hepatocytes [PDF]

, 2020
BACKGROUND: Naturally occurring variation in Membrane-bound O-acyltransferase domain-containing 7 (MBOAT7), encoding for an enzyme involved in phosphatidylinositol acyl-chain remodelling, has been associated with fatty liver and hepatic disorders.
Davidson, Nicholas O, et al,, Meroni, Marica   +2 more
core   +1 more source

SOAT1 exacerbates tumor progression by promoting YAP signaling activation and attenuating endoplasmic reticulum stress

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Metabolic reprogramming is a hallmark of malignancy, with profound alterations in cellular metabolism driving cancer progression. However, the precise mechanisms by which these metabolic changes promote tumor growth remain poorly understood.
Fan Wang, Qianyu Li, Yifei Qian, Yu Tong, Songling Li, Wenyun Guo, Linfeng Li, Zijun Zhu, Wei‐Qiang Gao, Yanfeng Liu   +9 more
doaj   +1 more source

Intracellular cholesterol transporters and modulation of hepatic lipid metabolism: implications for diabetic dyslipidaemia and steatosis [PDF]

, 2014
Caridis, Anna-Maria, Dolan, Sharron, Graham, Annette, Soffientini, Ugo   +3 more
core   +1 more source

Die Funktion des Responseregulators ARR2 in der Entwicklung von Arabidopsis thaliana [PDF]

, 2004
In dieser Arbeit konnte mittels physiologischer Experimente, Expressionsanalysen, Phosphorylierungsassays und Transaktivierungsanalysen eine komplexe Funktion von ARR2 in verschiedenen Signaltransduktionswegen von Arabidopsis aufgedeckt werden.
Haß, Claudia
core  

Penthorum chinense Pursh extract ameliorates alcohol-related fatty liver disease in mice via the SIRT1/AMPK signaling axis

Heliyon
Penthorum chinense Pursh (P. chinense), a functional food, has been applied to protect the liver against alcohol-related fatty liver disease (ALD) for a long history in China.
Hui Zhuge, Yan Pan, Shanglei Lai, Kaixin Chang, Qinchao Ding, Wenjing Cao, Qing Song, Songtao Li, Xiaobing Dou, Bin Ding   +9 more
doaj   +1 more source

Sterol O-Acyltransferase 1 (SOAT1, ACAT) Is a Novel Target of Steroidogenic Factor-1 (SF-1, NR5A1, Ad4BP) in the Human Adrenal [PDF]

, 2011
Bruno Ferraz‐de‐Souza, Rebecca E. Hudson‐Davies, Lin Lin, Rahul Parnaik, Michael Hubank, Mehul Dattani, John C. Achermann   +6 more
openalex   +3 more sources

Review article

, 2019
In eukaryotic cells, the trans-Golgi network (TGN) serves as a platform for secretory cargo sorting and trafficking. In recent years, it has become evident that a complex network of lipid-lipid and lipid-protein interactions contributes to these key ...
Hausser, A., von Blume, J.
core   +1 more source

Biosynthesis of Phytosterol Esters: Identification of a Sterol O-Acyltransferase in Arabidopsis [PDF]

, 2007
Qilin Chen, Lee Steinhauer, Joe K. Hammerlindl, W. A. Keller, Jitao Zou   +4 more
openalex   +1 more source

Cholesterol, Bile Acid, And Lipoprotein Metabolism In Two Strains Of Hamster, One Resistant, The Other Sensitive (LPN) To Sucrose-Induced Cholelithiasis [PDF]

, 2000
A comprehensive study of cholesterol, bile acid, and lipoprotein metabolism was undertaken in two strains of hamster that differed markedly in their response to a sucrose-rich/low fat diet.
Blanchard, Geraldine, Boehler, Nathalie, Combettes-Souverain, Murielle, Eckhardt, Erik, Ferezou, Jacqueline, Lutton, Claude, Milliat, Fabien, Riottot, Michel, Serougne, Colette, Smith, Jeffery L., Souidi, Maamar   +10 more
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