Biosynthesis of Phytosterol Esters: Identification of a Sterol O-Acyltransferase in Arabidopsis [PDF]
Plant Physiology, 2007 Fatty acyl esters of phytosterols are a major form of sterol conjugates distributed in many parts of plants. In this study we report an Arabidopsis (Arabidopsis thaliana) gene, AtSAT1 (At3g51970), which encodes for a novel sterol O-acyltransferase.
Qilin Chen +4 more
semanticscholar +6 more sources
Cholesterol esters (CE) derived from hepatic sterol O-acyltransferase 2 (SOAT2) are associated with more atherosclerosis than CE from intestinal SOAT2. [PDF]
Circ Res, 2014 Zhang J +7 more
europepmc +4 more sources
Dysregulated expression of sterol O-acyltransferase 1 (Soat1) in the hair shaft of Hoxc13 null mice. [PDF]
Exp Mol Pathol, 2015 The cholesterol-metabolizing enzyme sterol O-acetyltransferase (SOAT1) is implicated in an increasing number of biological and pathological processes in a number of organ systems, including the differentiation of the hair shaft. While the functional and regulatory mechanisms underlying these diverse functional roles remain poorly understood, the ...
Potter CS +6 more
europepmc +7 more sources
Mutations in sterol O-acyltransferase 1 (Soat1) result in hair interior defects in AKR/J mice. [PDF]
J Invest Dermatol, 2010 Wu B +9 more
europepmc +6 more sources
PRD125, a potent and selective inhibitor of sterol O-acyltransferase 2 markedly reduces hepatic cholesteryl ester accumulation and improves liver function in lysosomal acid lipase-deficient mice. [PDF]
J Pharmacol Exp Ther, 2015 Lopez AM +6 more
europepmc +3 more sources
Celludinones, new inhibitors of sterol O-acyltransferase, produced by Talaromyces cellulolyticus BF-0307 [PDF]
The Journal of Antibiotics, 2018 New indanones, designated celludinones A ((±)-1) and B (2), were isolated from the culture broth of the fungal strain Talaromyces cellulolyticus BF-0307. The structures of celludinones were elucidated by spectroscopic data, including 1D and 2D NMR.
Taichi Ohshiro +4 more
semanticscholar +4 more sources
7-Chlorofolipastatin, an inhibitor of sterol O-acyltransferase, produced by marine-derived Aspergillus ungui NKH-007 [PDF]
The Journal of Antibiotics, 2016 A new depsidone, named 7-chlorofolipastatin, and five known structurally related depsidones were isolated from the culture broth of the marine-derived fungus Aspergillus ungui NKM-007 by solvent extraction and HPLC using an octadecylsilyl column. The structure of 7-chlorofolipastatin was elucidated by various spectroscopic data including 1D and 2D NMR ...
Ryuji Uchida +6 more
semanticscholar +5 more sources
Regulation of lipid metabolism-related gene expression in whole blood cells of normo- and dyslipidemic men after fish oil supplementation [PDF]
Lipids in Health and Disease, 2012 Background Beneficial effects of omega-3 polyunsaturated fatty acids (n-3 PUFAs) on the lipid levels of dyslipidemic subjects are widely described in the literature. However, the underlying molecular mechanisms are largely unknown.
Schmidt Simone +6 more
doaj +4 more sources
Clonoamide, a new inhibitor of sterol O-acyltransferase, produced by Clonostachys sp. BF-0131 [PDF]
The Journal of Antibiotics, 2015 A new compound designated as clonoamide was isolated from a culture broth of the fungus Clonostachys sp. BF-0131 by solvent extraction, Diaion HP20 column chromatography, octadecylsilyl column chromatography and preparative HPLC as an inhibitor of sterol O-acyltransferase (SOAT). The structure of clonoamide was elucidated as 2-oxo-9E,11E-tridecandienyl
Keisuke Kobayashi +4 more
semanticscholar +4 more sources
Chinese Journal of Physiology, 2023 Recently, evidence has shown that microRNA-100-3p (miR-100-3p) has been revealed as a tumor suppressor in diverse human diseases, while its capability in lung cancer warrants further validation. In this work, we aimed to discuss the impact of sevoflurane
Bicheng Fu +7 more
doaj +2 more sources