Results 61 to 70 of about 12,786 (155)
Generation and characterization of a mitotane-resistant adrenocortical cell line [PDF]
, 2020 Mitotane is the only drug approved for the therapy of adrenocortical carcinoma (ACC). Its clinical use is limited by the occurrence of relapse during therapy.
Bachmann, Sebastian +14 more
core +2 more sources
European Journal of Clinical Investigation, EarlyView.This consensus highlights critical research gaps in obesity epidemiology, phenotypic heterogeneity and clinical management, calling for advanced methodologies, collaborative strategies and innovative policies to mitigate the global obesity epidemic and its socio‐economic impacts.
Federico Carbone +28 more
wiley +1 more source
Side-chain oxidized oxysterols as metabolic regulators in liver and brain [PDF]
, 2014 Oxysterols are oxygenated derivatives of cholesterol characterized by a very short half-life and their ability to pass lipophilic membranes easily, thus they are considered as important intermediates in cholesterol excretion pathways and its ...
Ali, Zeina M. F.
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Hepatology Research, EarlyView.In metabolic dysfunction‐associated steatotic liver disease/metabolic dysfunction‐associated steatohepatitis patients aged <60 years, high serum β‐cryptoxanthin concentrations were inversely associated with CVD mortality. Abstract Aim High cardiovascular disease (CVD) mortality occurred among metabolic dysfunction‐associated steatotic liver disease ...
Qian‐Qian Wang +5 more
wiley +1 more source
Interplay between phospholipids and digalactosyldiacylglycerol in phosphate limited oats [PDF]
, 2009 Phosphate is an essential nutrient. In most soils it is limiting, which has resulted in that phosphate is supplied as fertilizer to increase crop yield.
Tjellström, Henrik
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Journal of Gastroenterology and Hepatology, EarlyView.ABSTRACT Background and Aim Metabolic dysfunction associated steatotic liver disease (MASLD) is the predominant cause of chronic liver disease, with dysregulation of bile acid (BA) metabolism and intestinal microbiota being intricately associated with MASLD progression.
Junjun Wang +7 more
wiley +1 more source
Enhanced fatty acid oxidation in adipocytes and macrophages reduces lipid-induced triglyceride accumulation and inflammation [PDF]
, 2015 Lipid overload in obesity and type 2 diabetes is associated with adipocyte dysfunction, inflammation, macrophage infiltration, and decreased fatty acid oxidation (FAO). Here, we report that the expression of carnitine palmitoyltransferase 1A (CPT1A), the
Belén Peral +16 more
core +2 more sources
Plant Biology, EarlyView.Overexpression of jojoba wax ester synthase in poplar causes accumulation of intracellular lipids in leaves and reduced stomatal conductance with higher water‐use efficiencies in the transgenic lines. Abstract Poplars are important fast‐growing, water‐spending biomass tree crops.
A. Amirkhosravi +7 more
wiley +1 more source
Sterol-binding proteins in late endosomes : Regulation of endosome motility and lipid metabolism [PDF]
, 2011 Despite its bad reputation in the mass media, cholesterol is an indispensable constituent of cellular membranes and vertebrate life. It is, however, also potentially lethal as it may accumulate in the arterial intima causing atherosclerosis or elsewhere ...
Uronen, Riikka-Liisa
core
Peroxisomal and mitochondrial enzymes involved in lipid metabolism : studies on function and regulation [PDF]
, 2013 Fatty acids constitute a major part of the energy that we obtain from the diet and are also the principal source for mammals to store energy. To use the incoming or stored fatty acids as energy, the fatty acids needs to be metabolized of which the ...
Tillander, Veronika
core +1 more source