Results 71 to 80 of about 17,732 (155)

Systemic Therapy for Paediatric Stevens–Johnson Syndrome and Toxic Epidermal Necrolysis: A Systematic Review of Current Evidence and Limitations

open access: yesJournal of Paediatrics and Child Health, EarlyView.
ABSTRACT Aim The role of systemic therapy in paediatric Stevens–Johnson Syndrome (SJS) and Toxic Epidermal Necrolysis (TEN) remains undefined. Management is primarily guided by observational data and variable practice patterns. This systematic review aims to integrate recent evidence and evaluate clinical outcomes associated with systemic therapies in ...
Samantha Ting   +3 more
wiley   +1 more source

Development of Multidisciplinary Consensus‐Informed Guidance for the Management of Paediatric Stevens–Johnson Syndrome and Toxic Epidermal Necrolysis Among Clinicians From Australasian Tertiary Referral Hospitals

open access: yesJournal of Paediatrics and Child Health, EarlyView.
ABSTRACT Background Paediatric Stevens–Johnson syndrome/toxic epidermal necrolysis (SJS/TEN) is a rare, severe mucocutaneous reaction requiring coordinated multidisciplinary care. Existing guidelines provide evidence‐based recommendations, but implementation across tertiary paediatric hospitals requires practical consensus on local resources.
Patrick David Mahar   +32 more
wiley   +1 more source

Acute lower leg transcutaneous electrical nerve stimulation increases leg blood flow and exercise capacity in patients with peripheral arterial disease

open access: yesExperimental Physiology, EarlyView.
Abstract We tested the hypothesis that two different durations of lower leg transcutaneous electrical nerve stimulation (TENS) increase post‐TENS popliteal artery blood flow (PABF), popliteal vascular conductance (PVC), and 6‐min walk distance (6MWD) in patients with peripheral artery disease (PAD).
Thomas K. Pellinger   +7 more
wiley   +1 more source

Dispelling Myths and Misunderstandings About Defining and Remediating Dyslexia

open access: yesDyslexia, Volume 32, Issue 4, November 2026.
ABSTRACT Despite a strong base of scientifically supported research on dyslexia, pervasive misunderstandings continue, particularly in the United States, where state legislation, instructional practices and parent advocacy intersect in ways that influence how dyslexia is identified and treated.
Christy R. Austin   +4 more
wiley   +1 more source

Stevens Johnson Syndrome induced by a combination of lamotrigine and valproic acid in a patient with bipolar disorder: A case report

open access: yesPsychiatry and Clinical Psychopharmacology, 2021
Stevens Johnson syndrome is a severe and potentially lifethreatening cutaneous reaction associated with lamotrigine. The incidence of developing Steven- Johnson syndrome during lamotrigine therapy is low.
Uğur Öner, Julide Güler, Elif Yılmaz
doaj  

Evaluation of conjunctival bacterial flora in patients with Stevens-Johnson Syndrome

open access: yesClinics, 2014
OBJECTIVE: To determine the conjunctival bacterial flora present in patients with Stevens-Johnson syndrome. METHODS: A prospective study of the conjunctival bacterial flora was performed in 41 eyes of 22 patients with Stevens-Johnson syndrome.
Luciana Frizon   +6 more
doaj   +1 more source

Indirect Comparison of Neoadjuvant Treatment Strategies for Muscle‐Invasive Bladder Cancer: ddMVAC and Perioperative Durvalumab‐Gemcitabine‐Cisplatin Versus Gemcitabine‐Cisplatin: A Systematic Review and Network Meta‐Analysis of Randomised Controlled Trials

open access: yesInternational Journal of Cancer, Volume 159, Issue 8, Page 1962-1973, 15 October 2026.
Optimizing neoadjuvant therapy for muscle‐invasive bladder cancer patients who are eligible for cisplatin remains difficult, owing particularly to high toxicity and recurrence rates. This meta‐analysis compared dose‐dense methotrexate, vinblastine, doxorubicin, and cisplatin (ddMVAC) against durvalumab plus gemcitabine‐cisplatin (D‐GC) and GC alone ...
Maurin Helen Mangold   +12 more
wiley   +1 more source

Effect of Implementing a Dashboard With or Without a Best Practice Alert on HLA‐B*58:01 Testing Rates Among Allopurinol Users at VA Medical Centers

open access: yesArthritis Care &Research, Volume 78, Issue 9, Page 1265-1269, September 2026.
Objective The American College of Rheumatology recommends HLA‐B*58:01 allele testing before the initiation of allopurinol, specifically among Asian and African American/Black patients, due to their increased risk for severe hypersensitivity reactions. However, testing rates remain low at many health care facilities.
Abimbola Fadairo‐Azinge   +6 more
wiley   +1 more source

Identification of antibiotic allergies in children using prescribing patterns in the electronic medical record

open access: yesBritish Journal of Clinical Pharmacology, Volume 92, Issue 9, Page 3161-3168, September 2026.
Background By age three, 5%–75% of children have a documented antibiotic allergy (AL). Despite this prevalence, recognition remains low because of limited clinician knowledge and time. Our study evaluates a novel approach to identifying AL using electronic medical record (EMR) prescription patterns.
Georgia Koutsaplis   +5 more
wiley   +1 more source

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