Results 81 to 90 of about 17,732 (155)
ABSTRACT Background T‐cell–engaging bispecific antibodies are increasingly utilised in haematological malignancies and are beginning to be adopted in solid‐tumour treatment protocols. Cytokine release syndrome and neurotoxicity are well recognised, but target‐specific dermatological adverse event reporting patterns remain poorly defined.
Saikat Mandal +2 more
wiley +1 more source
Stevens-Johnson syndrome with overlapping features of DRESS syndrome: A report of two cases
Stevens-Johnson syndrome and drug reaction with eosinophilia and systemic symptoms are severe cutaneous adverse reactions to drugs that are generally considered distinct entities.
Laura D Chin +3 more
doaj +2 more sources
Platelet FcɣRIIa Expression Refines Clinical Risk Assessment After Myocardial Infarction
ABSTRACT Background In patients with myocardial infarction (MI), quantifying expression of platelet FcɣRIIa (pFCG) stratifies risk of subsequent MI, stroke, and death. Aims Assess the prognostic implications of clinical risk alone and in combination with the pFCG test.
David J. Schneider +9 more
wiley +1 more source
A Challenging Case of Acute Methotrexate Toxicity
ABSTRACT Catastrophic methotrexate toxicity, characterized by life‐threatening pancytopenia and neutropenic enterocolitis, may occur even after a single low therapeutic dose, particularly in patients with renal impairment or dehydration. Early recognition and prompt multidisciplinary management are essential to improve outcomes.
Sahel Asgari +3 more
wiley +1 more source
Prompt versus delayed amniotic membrane application in a patient with acute Stevens-Johnson syndrome
Jessica B Ciralsky, Kimberly C SippelDepartment of Ophthalmology, Weill Cornell Medical College, New York, NY, USABackground: Stevens-Johnson syndrome is often associated with blinding ocular surface cicatricial sequelae.
Ciralsky JB, Sippel KC
doaj
ABSTRACT Stevens‐Johnson syndrome/toxic epidermal necrolysis (SJS/TEN) overlap is a rare, life‐threatening mucocutaneous reaction typically induced by medications. Reports from Central America remain scarce. We present two contrasting cases of SJS/TEN overlap from Nicaragua.
Marvin Alfaro +2 more
wiley +1 more source
ABSTRACT We report a case of carbamazepine‐induced Stevens‐Johnson syndrome/toxic epidermal necrolysis (SJS/TEN) overlap in an 11‐year‐old Ugandan boy who presented with fever, facial swelling, ocular redness with photophobia, painful oral ulceration, and widespread epidermal detachment involving more than 10% of the body surface area.
Abdisalam Ahmed Sandeyl +5 more
wiley +1 more source
GWAS of Tau‐Neurodegeneration Mismatch Identifies New Risk Loci for Susceptibility to Tau
This GWAS of tau/neurodegeneration mismatch in 794 ADNI and A4 participants identified two genome‐wide significant loci, STXBP6 and AKAP9. The risk alleles were associated with greater‐than‐expected neurodegeneration for a given tau burden, suggesting these genes may influence susceptibility to tau‐related neuronal injury.
Fardin Nabizadeh +305 more
wiley +1 more source
Taurine and Metabolic Diseases: Molecular Mechanisms and Therapeutic Implications
The dietary sources of taurine, as well as its protective effects and mechanisms in metabolism‐related diseases and metabolic disorder–associated ocular and cerebral injuries. ABSTRACT Taurine (Tau) is a sulfur‐containing amino acid prevalent in animal tissues and primarily acquired through dietary sources.
Xiaojie Ma, Zhijian Rao, Lifang Zheng
wiley +1 more source
Purpose: To review the possible aetiological factors, ocular complications and their management in patients of Stevens-Johnson syndrome with ocular involvement, seen at a tertiary eye care centre.
Kompella Viswanadh +5 more
doaj

