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Current Pharmacogenetic Perspective on Stevens-Johnson Syndrome and Toxic Epidermal Necrolysis
Frontiers in Pharmacology, 2021 Adverse drug reactions are a public health issue that draws widespread attention, especially for Stevens-Johnson syndrome (SJS) and toxic epidermal necrolysis (TEN) which have high mortality and lack of efficacious treatment.
Lin Cheng
semanticscholar +1 more source
F1000Research, 2020 Stevens-Johnson syndrome (SJS) and toxic epidermal necrolysis (TEN) are life-threatening diseases characterized by detachment of the epidermis and mucous membrane.
A. Hasegawa, R. Abe
semanticscholar +1 more source
Labial adhesions caused by Stevens–Johnson syndrome
Dermatologica Sinica, 2015 Vulvovaginal sequelae in Stevens–Johnson syndrome have been widely described in published literature, however, there is no consensus regarding effective preventive treatments.
Jung Mi Byun +5 more
doaj +1 more source
Carbamazepine-induced Life-threatening Stevens-Johnson Syndrome and Agranulocytosis: The Maiden Case [PDF]
Journal of Clinical and Diagnostic Research, 2016 Stevens-Johnson syndrome is one of the few dermatological emergencies in clinical practice. The syndrome is often secondary to the usage of drugs, of which allopurinol, penicillins, sulfa drugs, ibuprofen, sodium valproate, phenytoin, lamotrigine and ...
A. Avinash +4 more
doaj +1 more source
Study of the ocular findings in Stevens-Johnson syndrome patients from a tertiary ophthalmologic center [PDF]
, 2009 PURPOSE: To evaluate the epidemiology, possible etiologic factors, complications and treatment of a group of patients with ocular complications secondary to Stevens-Johnson syndrome.
Cunha, Marcelo +4 more
core +3 more sources
Identifying the incidence of rash, Stevens-Johnson syndrome and toxic epidermal necrolysis in patients taking lamotrigine: a systematic review of 122 randomized controlled trials [PDF]
Anais Brasileiros de Dermatologia, 2017 Lamotrigine is an antiepileptic drug used for the treatment of epilepsy, bipolar disorder and numerous off-label uses. The development of rash significantly affects its use. The most concerning of these adverse reactions is Stevens-Johnson syndrome/toxic
Romi Bloom, Kyle T. Amber
doaj +2 more sources
Amniotic membrane transplantation for severe acute cases of chemical ocular burn and Stevens-Johnson syndrome [PDF]
, 2009 PURPOSE: To study the therapeutic potential of amniotic membrane transplantation in cases of severe acute chemical ocular burn and Stevens-Johnson syndrome.
Barros, Sabrina Leite de +4 more
core +2 more sources
The Journal of Emergency Medicine, 1984 The clinical manifestations, including variations, of the Stevens-Johnson syndrome (SJS) are reviewed. Lesions of the skin, eye, and mucous membranes are described and discussed. The potential complications and therapeutic approaches are outlined. Finally, the review discusses the controversy over the use of systemic corticosteroids in this syndrome.
Professor, Department of Pharmacy Practice. College of Pharmacy, University of Florida, Gainesville, USA ( host institution ) +2 more
openaire +3 more sources
Amniotic membrane transplantation [PDF]
, 2000 Amniotic membrane transplantation has been used as an alternative for ocular surface reconstruction. Indications for amniotic membrane transplantation include persistent epithelial defects, pterygium, Stevens-Johnson syndrome, ocular cicatricial ...
Moreira, Hamilton +1 more
core +2 more sources
Current Oncology, 2021 (1) Background. Stevens–Johnson syndrome (SJS) and toxic epidermal necrolysis (TEN) are severe mucocutaneous reactions, characterized by extensive necrosis and detachment of the epidermis. (2) Case presentation. We present a case of a 46-year-old patient
Andrej Cokan +2 more
doaj +1 more source