Early accumulation of cytotoxic byproducts of vitamin A (bisretinoids) is a prominent pathological feature of Stargardt disease (STGD1). Tinlarebant is an orally administered drug that targets plasma retinol binding protein 4 (RPB4) to reduce vitamin A ...
Berlin, P. +4 more
core
Lens Opacity in ABCA4-Associated Stargardt Disease Patients in the ProgStar Study. [PDF]
Invest Ophthalmol Vis SciIbukun F +14 more
europepmc +1 more source
Abca4 Knockdown in the Cone-Rich Rodent Psammomys Obesus Leads to Stargardt's Disease-Like Progressive Retinal Degeneration. [PDF]
Invest Ophthalmol Vis SciEstay-Ahumada CE +7 more
europepmc +1 more source
Genetic Correlates of Phenotypic Variability in c.5882G>A p.(Gly1961Glu)-Associated Stargardt Disease. [PDF]
Invest Ophthalmol Vis SciPas JAAH +8 more
europepmc +1 more source
Mesopic microperimetry in Stargardt disease: Application and reliability. [PDF]
Acta OphthalmolKootstra SH +12 more
europepmc +1 more source
A novel modifier gene therapy to treat Stargardt disease: Phase 1 GARDian1 Trial Insights. [PDF]
Eye (Lond)Khanani AM +4 more
europepmc +1 more source
Dysregulated DNA Methylation in <i>Abca4<sup>-/-</sup></i> Retinal Pigment Epithelium: Insights into Early Stage of Stargardt Disease. [PDF]
Int J Mol SciDave A +6 more
europepmc +1 more source
A Comparison of Randomizing Either One Eye or Both Eyes in Clinical Trials for Stargardt Disease Type 1. [PDF]
Ophthalmol SciPas JAAH +5 more
europepmc +1 more source
More insights from Abca4<sup>-/-</sup> mouse models of recessive Stargardt disease. [PDF]
J Biol ChemZhao J +4 more
europepmc +1 more source
Nutritional supplements: current evidence for retinitis pigmentosa and Stargardt disease. [PDF]
Curr Opin OphthalmolBarthelemy N +4 more
europepmc +1 more source