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Therapy Approaches for Stargardt Disease [PDF]
Biomolecules, 2021 Despite being the most prevalent cause of inherited blindness in children, Stargardt disease is yet to achieve the same clinical trial success as has been achieved for other inherited retinal diseases. With an early age of onset and continual progression
Elena Piotter +2 more
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American Journal of Ophthalmology Case Reports, 2022 Purpose: To report a case of late-onset Stargardt disease, discuss the differential diagnosis, and review the role of vitamin A supplementation in Stargardt disease.
Joseph B. Alsberge, Anita Agarwal
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Photorefractive keratectomy in a patient with Stargardt disease: Case report [PDF]
SAGE Open Medical Case ReportsThis case presents a successful outcome following photorefractive keratectomy surgery in a patient with Stargardt disease. A 23-year-old female with a history of Stargardt disease oculus uterque and high myopia oculus uterque presented for refractive ...
Alyssa Pasvantis +2 more
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Stem cell therapy as treatment for Stargardt disease [PDF]
Therapeutic Advances in OphthalmologyStargardt disease or Juvenile Macular Degeneration is a rare genetic disorder caused by a mutation in the ABCA4 gene that results in degeneration of the macula and loss of central vision.
Erica Marks +3 more
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Identification and functional characterization of ABCA4 gene variants in three patients with Stargardt disease or retinitis pigmentosa [PDF]
Frontiers in GeneticsIntroductionThe diversity of phenotypes, ranging from inherited retinal dystrophies (such as Stargardt disease 1, cone–rod dystrophy 3, and retinitis pigmentosa 19) to late-onset age-related macular degeneration 2, has been attributed to loss-of-function
Qi Luo +11 more
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A Comparison of Randomizing Either One Eye or Both Eyes in Clinical Trials for Stargardt Disease Type 1 [PDF]
Ophthalmology ScienceObjective: Designing a clinical trial for rare diseases such as Stargardt disease type 1 is challenging due to the limited patient population. In traditional clinical trial designs for inherited retinal diseases, often only 1 eye of each patient is used ...
Jeroen A.A.H. Pas, MD +5 more
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Clinical classification of Stargardt disease. [PDF]
Graefes Arch Clin Exp Ophthalmol, 2023 Contains fulltext : 305742.pdf (Publisher’s version ) (Open Access)
Pas JAAH, Dhooge PPA, Hoyng CB.
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Stem Cell Therapy in Stargardt Disease: A Systematic Review [PDF]
Journal of Ophthalmic & Vision Research, 2023 This article aimed to review current literature on the safety and efficacy of stem cell therapy in Stargardt disease. A comprehensive literature search was performed, and two animal and eleven human clinical trials were retrieved.
Atousa Moghadam Fard +3 more
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Artificial intelligence for assessment of Stargardt macular atrophy
Neural Regeneration Research, 2022 Stargardt disease (also known as juvenile macular degeneration or Stargardt macular degeneration) is an inherited disorder of the retina, which can occur in the eyes of children and young adults.
Ziyuan Wang, Zhihong Jewel Hu
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American Journal of Ophthalmology Case Reports, 2022 Purpose: To illustrate the potential diagnostic confusion between Batten disease and Stargardt disease created by associated signs and symptoms. Observations: A six-year-old girl with vision loss and prominent behavioral changes and overlooking was ...
Michael C. Brodsky, Arlene Drack
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