Results 21 to 30 of about 4,867,114 (192)

Generation of iPSC lines from three Stargardt patients carrying bi-allelic ABCA4 variants

Stem Cell Research, 2023
Stargardt disease, a progressive retinal disorder, is associated with bi-allelic variants in ABCA4, a protein that is expressed in the retina. Induced pluripotent stem cell lines (RMCGENi005-A, SCTCi018-A, SCTCi017-A) were generated by lentivirus ...
Dyah W. Karjosukarso, Femke Bukkems, Lonneke Duijkers, Nico Leijsten, Carel B. Hoyng, Rob W.J. Collin   +5 more
doaj   +1 more source

Monitoring and Management of the Patient with Stargardt Disease

Clinical Optometry, 2019
Maria Vittoria Cicinelli, Marco Battista, Vincenzo Starace, Maurizio Battaglia Parodi, Francesco Bandello Department of Ophthalmology, University Vita-Salute, IRCCS Ospedale San Raffaele, Milan, ItalyCorrespondence: Maria Vittoria CicinelliDepartment of ...
Cicinelli MV, Battista M, Starace V, Battaglia Parodi M, Bandello F   +4 more
doaj   +4 more sources

Stargardt's Connected Research Network Inaugural Meeting: Landscape Review and Horizon Scanning of Stargardt Disease. [PDF]

Transl Vis Sci Technol
Purpose: The purpose of this study was to update the recent progress in the diagnosis, management, and treatments for Stargardt disease. Methods: On November 22, 2024, Stargardt's Connected held its inaugural meeting of their Research Network, attended ...
Britten-Jones AC, Al-Khuzaei S, Rizzi M, Crossland MD, Rozanowska MB, Mendes BS, de Guimaraes TAC, Daich Varela M, Sumodhee D, Woof WA, Khan S, Girach A, Downes SM, Cheetham ME, Piccolo D, Ayton LN, Brandão ML, Scholl HPN, Skilton A, Tailor B, Michaelides M, Pontikos N, Stargardt's Connected.   +22 more
europepmc   +6 more sources

Foveal Sparing in Stargardt Disease [PDF]

Investigative Opthalmology & Visual Science, 2014
To provide a clinical and genetic description of a patient cohort with Stargardt disease (STGD1) with identifiable foveal sparing.Patients with retinal atrophy (defined as an absence of autofluorescence) that surrounded the fovea by at least 180° and did not include the fovea were defined as having foveal sparing; eyes with visual acuity (VA) worse ...
Huet, R.A.C. van, Bax, N.M., Westeneng-Van Haaften, S.C., Muhamad, M., Zonneveld-Vrieling, M.N., Hoefsloot, L.H., Cremers, F.P.M., Boon, C.J.F., Klevering, B.J., Hoyng, C.B.   +9 more
openaire   +4 more sources

Exome sequencing analysis identifies compound heterozygous mutation in ABCA4 in a Chinese family with Stargardt disease. [PDF]

PLoS ONE, 2014
Stargardt disease is the most common cause of juvenile macular dystrophy. Five subjects from a two-generation Chinese family with Stargardt disease are reported in this study. All family members underwent complete ophthalmologic examinations. Patients of
Yu Zhou, Siyu Tao, Hui Chen, Lulin Huang, Xiong Zhu, Youping Li, Zhili Wang, He Lin, Fang Hao, Zhenglin Yang, Liya Wang, Xianjun Zhu   +11 more
doaj   +1 more source

Using Ensemble OCT-Derived Features beyond Intensity Features for Enhanced Stargardt Atrophy Prediction with Deep Learning

Applied Sciences, 2023
Stargardt disease is the most common form of juvenile-onset macular dystrophy. Spectral-domain optical coherence tomography (SD-OCT) imaging provides an opportunity to directly measure changes to retinal layers due to Stargardt atrophy.
Zubin Mishra, Ziyuan Wang, SriniVas R. Sadda, Zhihong Hu   +3 more
doaj   +1 more source

Retinal boundary segmentation in stargardt disease optical coherence tomography images using automated deep learning [PDF]

, 2020
Purpose: To use a deep learning model to develop a fully automated method (fully semantic network and graph search [FS-GS]) of retinal segmentation for optical coherence tomography (OCT) images from patients with Stargardt disease.
Kugelman, J., Chen, Y., Vallis, N., Chen, Y, Collins, MJ, Chen, F.K., Huang, D., Alonso-Caneiro, D., Alonso-Caneiro, D, Huang, D, Chen, FK, Collins, M.J., Arunachalam, S, Arunachalam, S., Kugelman, J, Vallis, N   +15 more
core   +1 more source

Automated segmentation and feature discovery of age-related macular degeneration and Stargardt disease via self-attended neural networks

Scientific Reports, 2022
Age-related macular degeneration (AMD) and Stargardt disease are the leading causes of blindness for the elderly and young adults respectively. Geographic atrophy (GA) of AMD and Stargardt atrophy are their end-stage outcomes.
Ziyuan Wang, Srinivas Reddy Sadda, Aaron Lee, Zhihong Jewel Hu   +3 more
doaj   +1 more source

Multimodal Imaging in a Case of Stargardt’s Disease

Delhi Journal of Ophthalmology, 2022
Stargardt Disease is the most common macular dystrophy, and multimodal image can be used for diagnosis and monitoring of the disease.
Shruti Bhattacharya, Khushboo Chawla, Priyadarshi Gupta, Meenakshi Thakar   +3 more
doaj   +1 more source

Clinical profile and demographic distribution of Stargardt disease phenotypes: An Electronic medical record-driven big data analytics from a multitier eye care network

Indian Journal of Ophthalmology, 2023
Purpose: To describe the demographics and clinical profile of Stargardt disease in patients presenting a multitier ophthalmology hospital network in India.
Anthony Vipin Das, Ragukumar Venugopal, Brijesh Takkar, Sumant Sharma, Neelima Balakrishnan, Raja Narayanan, Deepika Parameswarappa, Srikanta Kumar Padhy   +7 more
doaj   +1 more source