Results 41 to 50 of about 4,867,114 (192)

PERIPAPILLARY ATROPHY IN STARGARDT DISEASE [PDF]

Retina, 2009
To demonstrate that Stargardt disease (STGD) can present with peripapillary atrophy.Retrospective case series. The medical records of 150 consecutive patients (300 eyes) were reviewed retrospectively from a STGD database from January 1999 to May 2007 at Columbia University's Harkness Eye Institute. STGD patients demonstrating peripapillary atrophy were
John C, Hwang, Jana, Zernant, Rando, Allikmets, Gaetano R, Barile, Stanley, Chang, R Theodore, Smith   +5 more
openaire   +2 more sources

Choroidal Caverns in Stargardt Disease

Investigative Opthalmology & Visual Science, 2022
To report choroidal caverns in patients affected by recessive Stargardt disease (STGD1) and to investigate its clinical features.Retrospective analysis of STGD1 patients recruited at the Regional Reference Center for Hereditary Retinal Degenerations at the Eye Clinic in Florence from 2012 to 2017.
Mucciolo, Dario Pasquale, Giorgio, Dario, Lippera, Myrta, Dattilo, Valeria, Passerini, Ilaria, Pelo, Elisabetta, Sodi, Andrea, Virgili, Gianni, Giansanti, Fabrizio, Murro, Vittoria   +9 more
openaire   +3 more sources

Stargardt Disease. Literature review

Oftalʹmologiâ
This literature review is devoted to the most common hereditary disease of the retina, called Stargardt disease. The work provides information on the epidemiology, molecular genetics, and pathophysiology of this disease.
R. S. Zhazybaev, A. L. Zhirov
doaj   +1 more source

Stem Cell Therapy in Stargardt Disease: A Systematic Review

Journal of Ophthalmic & Vision Research, 2023
This article aimed to review current literature on the safety and efficacy of stem cell therapy in Stargardt disease. A comprehensive literature search was performed, and two animal and eleven human clinical trials were retrieved.
Atousa Moghadam Fard, Reza Mirshahi, Masood Naseripour, Khalil Ghasemi Falavarjani   +3 more
doaj   +1 more source

A case of pentosan polysulfate maculopathy originally diagnosed as stargardt disease

American Journal of Ophthalmology Case Reports, 2020
Purpose: To describe a patient with a past diagnosis of Stargardt disease that was later determined to be pentosan polysulfate (PPS) maculopathy. Observations: The patient had clinical and imaging findings uncharacteristic of Stargardt disease.
Robin A. Vora, Amar P. Patel, Sam S. Yang, Ronald Melles   +3 more
doaj   +1 more source

LLMs and Stargardt's Disease

Journal of Surgery Care
Background/Objective: Stargardt's disease is the most common form of inherited juvenile macular degeneration affecting 1 in 8,000-10,000 individuals worldwide, with a slight predominance towards females. As large language models (LLMs) increasingly serve as sources of health information, understanding their effectiveness in providing accurate ...
Gloria Wu, Lochan Bojja, Aadjot Sidhu, Obaid Khan, Hrishi Paliath-Pathiyal, Bojia Liu, Margaret Wang, Ivan Chim   +7 more
openaire   +1 more source

Nonparametric Regression for Cost‐Effectiveness Analyses With Observational Data—A Tutorial

Health Economics, EarlyView.
ABSTRACT Healthcare decision‐making often requires selecting among multiple treatment options under budget constraints, particularly when one option is more effective but also more costly. Cost‐effectiveness analysis (CEA) provides a framework for evaluating whether the health benefits of a treatment justify its additional costs.
Jonas Esser, Mateus Maia, Judith E. Bosmans, Johanna Maria van Dongen   +3 more
wiley   +1 more source

Prime editing in neuropsychiatric disorders: From mutation‐specific target selection to clinical translation

Neuroprotection, EarlyView.
Abstract Prime editing, a novel clustered regularly interspaced short palindromic repeats (CRISPR)‐based technology, fuses a reverse transcriptase (RT) to an engineered CRISPR‐associated protein 9 (Cas9) and uses a prime editing guide RNA (pegRNA)‐encoded template.
Tianshan Ji, Yuan Zhang, Jinyi Zhao, Yiping Lu, Chengkun Wang   +4 more
wiley   +1 more source

Clinical and Molecular Characteristics of Childhood-Onset Stargardt Disease. [PDF]

, 2015
To describe the clinical and molecular characteristics of patients with childhood-onset Stargardt disease (STGD)
Robson, Anthony G., Moore, Anthony, Chana, Ravinder K., Holder, Graham E., Moore, Anthony T., Ozawa, Y, Wright, Genevieve A., Fujinami, K, Allikmets, Rando, Zernant, J, Chana, RK, Allikmets, R, Tsunoda, Kazushige, Ozawa, Yoko, Tsunoda, K, Fujinami, Kaoru, Wright, GA, Holder, GE, Moore, AT, Michaelides, M, Zernant, Jana, Robson, AG, Tsubota, K, Tsubota, Kazuo, Michaelides, Michel   +24 more
core   +1 more source

The optical coherence tomography and microperimetry biomarker evaluation in patients with geographic atrophy (OMEGA) study: Geographic atrophy progression in fundus autofluorescence ‐ OMEGA report 3

Acta Ophthalmologica, EarlyView.
Abstract Purpose To measure the progression of geographic atrophy (GA) in subjects with age‐related macular degeneration (AMD) in a natural history study. Methods We analysed fundus autofluorescence (FAF) images using a semiautomatic method (RegionFinder) to quantify the GA area in a monocentric study.
Philippe Valmaggia, Georg Ansari, Nadja Inglin, Nils Schärer, Hanna Zuche, Chrysoula Gabrani, Faady Yahya, Marco Cattaneo, Kristina Pfau, Andrea Giani, Marieh Esmaeelpour, Taffeta Chingning Yamaguchi, Christian Prünte, Hendrik P. N. Scholl, Nicolas Feltgen, Leopold Schmetterer, Maximilian Pfau, Peter M. Maloca   +17 more
wiley   +1 more source