Results 41 to 50 of about 971 (147)

Longitudinal Changes of Fundus Autofluorescence and Correlation With Visual Acuity in ABCA4-Associated Stargardt Disease. [PDF]

Invest Ophthalmol Vis Sci
PURPOSE: To assess cross-sectional and longitudinal relationships between fundus autofluorescence (FAF) and visual acuity (VA) in ABCA4-associated Stargardt disease (STGD1).
Ibukun F, Strauss RW, Rustam Z, Khan MJ, Cideciyan AV, Birch DG, Ho A, Sunness JS, Audo IS, Michaelides M, Zrenner E, Traboulsi EI, Bernstein P, Sadda S, Ip MS, West S, Kong X.   +16 more
europepmc   +2 more sources

Formulation and Evaluation of SNEDDS Loaded with Original Lipophenol for the Oral Route to Prevent Dry AMD and Stragardt’s Disease

Pharmaceutics, 2022
Dry age-related macular degeneration (Dry AMD) and Stargardt’s disease (STGD1) are common eye diseases, characterized by oxidative and carbonyl stress (COS)-inducing photoreceptor degeneration and vision loss.
Maxime Vincent, Laurianne Simon, Philippe Brabet, Philippe Legrand, Christophe Dorandeu, Josephine Lai Kee Him, Thierry Durand, Céline Crauste, Sylvie Begu   +8 more
doaj   +1 more source

ABCA4-Associated Stargardt Disease

, 2020
Contains fulltext : 218259.pdf (Publisher’s version ) (Open Access)Autosomal recessive Stargardt disease (STGD1) is associated with variants in the ABCA4 gene.
Khan, M., Cremers, F.P.M., Cremers, F.
core   +1 more source

Understanding degeneration and the capacity for reorganisation in the adult human visual cortex

, 2023
Stargardt Macular Dystrophy (STGD1) causes degeneration of the photoreceptors, predominantly constrained to the cones within the central retina, which causes a loss of high acuity vision within the central visual field.
Sheldon, Aislin
core   +1 more source

Lipofuscin-associated photo-oxidative stress during fundus autofluorescence imaging. [PDF]

PLoS ONE, 2017
PURPOSE:Current standards and guidelines aimed at preventing retinal phototoxicity during intentional exposures do not specifically evaluate the contribution of endogenous photosensitizers.
Michel M Teussink, Stanley Lambertus, Frits F de Mul, Malgorzata B Rozanowska, Carel B Hoyng, B Jeroen Klevering, Thomas Theelen   +6 more
doaj   +1 more source

Simultaneous expression of two pathogenic genes in four Chinese patients affected with inherited retinal dystrophy [PDF]

International Journal of Ophthalmology, 2020
"AIM: To describe the complex, overlapping phenotype of four Chinese patients with inherited retinal dystrophies (IRDs) who harbored two pathogenic genes simultaneously. METHODS: This retrospective study included 4 patients affected with IRDs.
Xiao-Zhen Liu, Tian-Chang Tao, Hong Qi, Shan-Na Feng, Ning-Ning Chen, Lin Zhao, Zhi-Zhong Ma, Gen-Lin Li, Li-Ping Yang   +8 more
doaj   +1 more source

Ciliary Defects in Inherited Retinal Diseases

Advanced Genetics, Volume 7, Issue 1, March 2026.
The photoreceptor cilium is a specialized sensory organelle essential for vision. This review systematically summarizes the structural and functional defects of the cilium that lead to inherited retinal diseases (IRDs). It highlights key pathogenic genes, elucidates molecular mechanisms of degeneration, and evaluates emerging therapeutic strategies ...
Guizhi Guo, Lin Li, Jun Zhou, Jie Ran
wiley   +1 more source

Choroidal Flow Signal in Late-Onset Stargardt Disease and Age-Related Macular Degeneration: An OCT-Angiography Study [PDF]

, 2018
Purpose: To investigate the choroidal blood flow in areas within and adjacent to retinal pigment epithelium (RPE) atrophy secondary to late-onset Stargardt disease (STGD1) and age-related macular degeneration (AMD). Methods: A total of 43 eyes (23 STGD1
Möller, Philipp T., Weber, Bernhard H. F., Neuhaus, Christine, Fleckenstein, Monika, Müller, Philipp L, de Sisternes, Luis, Stöhr, Heidi, Lindner, Moritz, Schmid, Matthias, Pfau, Maximilian, Herrmann, Philipp, Holz, Frank G., Weber, Bernhard HF, Müller, Philipp L., Schmitz-Valckenberg, Steffen, Möller, Philipp T, Holz, Frank G, Nadal, Jennifer   +17 more
core   +1 more source

Clinical and Genetic Spectrum of Stargardt Disease in Argentinean Patients

Frontiers in Genetics, 2021
PurposeTo describe the clinical and molecular spectrum of Stargardt disease (STGD) in a cohort of Argentinean patients.MethodsThis retrospective study included 132 subjects comprising 95 probands clinically diagnosed with STGD and relatives from 16 of ...
Marcela D. Mena, Angélica A. Moresco, Sofía H. Vidal, Diana Aguilar-Cortes, María G. Obregon, Adriana C. Fandiño, Juan M. Sendoya, Andrea S. Llera, Osvaldo L. Podhajcer   +8 more
doaj   +1 more source

Case series: The value of fundus autofluorescence in inherited macular disease

Optometry and Vision Science, Volume 103, Issue 3, March 2026.
ABSTRACT Purpose To evaluate the diagnostic utility of fundus autofluorescence (FAF) imaging in identifying and characterizing phenotypically classified inherited macular dystrophies. In this way, we aim to provide methods by which eye care practitioners can link FAF imaging and other clinical results or imaging modalities to aid their clinical ...
Marina Guro, Henrietta Wang, Jack Phu, Nimesh B. Patel, Kaitlyn A. Sapoznik, Hamza Shah, Michael Kalloniatis   +6 more
wiley   +1 more source