Results 101 to 110 of about 68,076 (258)

Rethinking Regional Innovation Systems in the Age of De‐Globalisation

Tijdschrift voor Economische en Sociale Geografie, EarlyView.
Abstract Since a few years, the international economic system has been experiencing the risk of growing fragmentation and uncertainty. However, research on Regional Innovation Systems (RIS) has yet to comprehensively engage with this phenomenon, despite its (spatial) significance. The paper contributes to addressing this gap, in particular by exploring
Francesco Molica, Francesco Cappellano, Teemu Makkonen   +2 more
wiley   +1 more source

Enhancing stroke risk stratification in atrial fibrillation through non‐Newtonian blood modelling and Gaussian process emulation

The Journal of Physiology, EarlyView.
Abstract figure legend Non‐Newtonian modelling and GPEs for stroke risk in atrial fibrilation patients. Abstract Atrial fibrillation (AF) is the most common heart arrhythmia, linked to a five‐fold increase in stroke risk. The left atrial appendage (LAA), prone to blood stasis, is a common thrombus formation site in AF patients.
Paolo Melidoro, Abdel Rahman Amr Sultan, Ahmed Qureshi, Magdi H. Yacoub, Khalil L. Elkhodary, Gregory Y. H. Lip, Natalie Montarello, Nishant Lahoti, Ronak Rajani, Magdalena Klis, Steven E. Williams, Oleg Aslanidi, Adelaide De Vecchi   +12 more
wiley   +1 more source

Differential Impact of Pharmacokinetic and Pharmacodynamic Variability on Response to Combination Therapy

Pharmacology Research &Perspectives, Volume 14, Issue 4, August 2026.
ABSTRACT Interindividual variability (IIV) in drug response complicates both fixed‐dose design and individualized therapy. Understanding how pharmacokinetic (PK) and pharmacodynamic (PD) processes jointly shape this variability is essential, particularly in combination therapy, where multiple interacting pathways influence outcomes. This study employed
Kuteesa R. Bisaso, Ronald Kadada Karyaburo, Jackson K. Mukonzo, Ene I. Ette   +3 more
wiley   +1 more source

Unintended Consequences of Life‐Saving Pharmaceutical Innovations: How HAART Led to the Resurgence of Syphilis

Health Economics, Volume 35, Issue 7, Page 1118-1130, July 2026.
ABSTRACT Syphilis, a sexually transmitted infection that can lead to serious health complications, was almost eliminated in the United States by 2000. But since then, its incidence began to increase, recently reaching a 60‐year peak. We suggest that the introduction of the highly active antiretroviral therapy (HAART) drug regimen, which transformed HIV
David Beheshti, Scott Cunningham, Nir Eilam   +2 more
wiley   +1 more source

Anatomical and Histological Characterization of the Intestine of Artibeus lituratus

Anatomia, Histologia, Embryologia, Volume 55, Issue 4, July 2026.
ABSTRACT The order Chiroptera is highly diverse and is the second richest among mammals. Approximately 181 species are known in Brazil, with varied feeding habits that make them essential for ecological functions such as seed dispersal and plant regeneration. Despite the importance of their ecosystem services, the anatomical and histological aspects of
Mário de Oliveira Magalhães, Jhonatan Henrique Lima da Rocha, Rair de Sousa Verde, Mateus de Oliveira Aquino, Janaira Mattos Amorim, Tamyres Izarelly Barbosa da Silva, Francisco Glauco de Araújo Santos   +6 more
wiley   +1 more source

Chemsex, sexualized drug use and emotional vulnerability among men who have sex with men (MSM): a one-month survey in a STI/HIV center

BMC Public Health
Background Chemsex, characterized by the intentional use of specific drugs to enhance sexual experiences during group sessions, represents a challenge for the health of some sexually active communities, such as men who have sex with men (MSM).
Stella Capodieci, Mauro Zaccarelli, Christof Stingone, Eugenia Giuliani, Valentina Cafaro, Laura Gianserra, Maria Gabriella Donà, Alessandra Latini, Massimo Giuliani   +8 more
doaj   +1 more source

Effects of Celecoxib and Etoricoxib on the Pharmacokinetics and Pharmacological Effects of Orally Administered Tramadol: A Randomised Controlled Trial

Basic &Clinical Pharmacology &Toxicology, Volume 139, Issue 1, July 2026.
ABSTRACT Tramadol is a widely used analgesic whose bioactivation to O‐desmethyltramadol is primarily mediated by cytochrome P450 2D6 (CYP2D6). Genetic variability and drug–drug interactions affecting CYP2D6 may influence tramadol pharmacokinetics and pharmacological effects.
Tuukka Saarikoski, Teijo I. Saari, Janne T. Backman, Mikko Niemi, Pertti J. Neuvonen, Klaus T. Olkkola, Kari Laine   +6 more
wiley   +1 more source

Editorial: Research and Development in Medical Education [PDF]

Research and Development in Medical Education, 2012
Mah a sti Alizadeh
doaj   +1 more source

Sustainability in Healthcare: The Role of Digital Technologies for Improving Patient Engagement

Business Ethics, the Environment &Responsibility, Volume 35, Issue 3, Page 2227-2278, July 2026.
ABSTRACT Sustainability in healthcare is getting considerable research attention as systems worldwide tend to balance environmental, social, and economic factors. In this context, digital technologies have demonstrated significant potential to enhance engagement among different consumer groups across various industries.
Francesco Schiavone, Federica Zeuli, Olga Grieva, Octavio Escobar, Fabian Bernhard   +4 more
wiley   +1 more source

Stage‐Specific Indicators of Northern Yellowtail Rockfish (Sebastes flavidus) Recruitment in the California Current Ecosystem

Fisheries Oceanography, Volume 35, Issue 4, Page 630-649, July 2026.
ABSTRACT Oceanographic and ecological conditions can be used to inform forecasts and decision‐making for marine resources, but the dominant drivers of recruitment variability remain poorly understood for many fish stocks. We developed a conceptual life‐history model of the oceanographic and ecological variables that influence the recruitment of ...
Megan L. Feddern, Amanda Darby, Kiva Oken, Nick Tolimieri   +3 more
wiley   +1 more source