Results 141 to 150 of about 6,246 (300)
A Piezo‐Mimetic Ionic Hydrogel Harnessing Joint Motion for Cartilage Repair
A piezo‐mimetic ionic hydrogel converts mechanical deformation into bioactive ionic currents via stress‐induced asymmetric ion migration. Coupled with sustained Mg2+ release, this mechano‐electrochemical platform bridges mechanical loading and cellular signaling, enabling load‐adaptive stimulation and enhanced cartilage regeneration. ABSTRACT Articular
Chenyuan Gao +14 more
wiley +1 more source
This study identifies the mechanosensor PIEZO1 as a key factor in promoting acute myeloid leukemia progression and uncovers a ferroptosis defense system mediated by PIEZO1‐HIF1A‐SLC7A11 axis that is essential for leukemia stem cell maintenance. This ferroptotic defense system may represent a unique vulnerability for leukemia stem cells, providing a ...
Tiantian Zhang +10 more
wiley +1 more source
We present the MyoRobot 3.0, an advanced platform that combines high‐resolution imaging with automated mechanical testing to improve the accuracy of single muscle fibre analysis. The system tracks fibre diameter changes during stretch, preventing major stress miscalculations.
Michael Haug +5 more
wiley +1 more source
Compressive Strength of Flat Panels with Z- and Hat-Section Stiffeners
Compression tests were conducted on 247 panels with Z-section stiffeners and 304 panels with hat-section stiffeners. Specimens were constructed from artificially aged Alclad 24S aluminum alloy with minimum guaranteed yield strengths of 64 and 57 ksi for ...
Weinberger, Robert A. +3 more
core
Strong‐yet‐ductile precipitation‐hardening alloys require novel microstructural complexity of precipitates in particularly at cryogenic condition, to constantly impart strain hardening of hard‐and‐brittle precipitates. The present work creates innovative structurally complex precipitates assembled with dispersed nanocores and a chemical‐heterogeneity ...
Shaohua Gao +9 more
wiley +1 more source
Full androgen deprivation (FAD) induces paracrine cholesterol in prostate cancer that drives the polarization of cancer‐associated fibroblasts (CAFs) and subsequent elevated matrix stiffness. Matrix stiffness in turn potentiates tumor cell survival under FAD pressure via dual mechanotransductive activation of the IRE1α‐XBP1s stress‐response axis ...
Shaojie Liu +20 more
wiley +1 more source
Fully programmable, in‐process 3D magnetization integrated with multi‐material printing enables soft magnetic systems with precise actuation and sensing. Discrete and continuous magnetization profiles drive bending, morphing, and locomotion, demonstrated through strain‐sensing elements, dragonfly‐inspired wings, octopus‐like tentacles, and a serpentine
Phillip Glass +5 more
wiley +1 more source
A numerical simulation approach for inflatable asymmetric geometries of orthotropic fabrics. [PDF]
Abdelmaseeh ASA +2 more
europepmc +1 more source
Design of Transverse Stiffeners in Plate Girders with Corrugated Web
This study reports investigations into the effect of relative flexural stiffness of intermediate stiffeners γ on the failure zone location in the corrugated web.
Basiński, Witold
core
How Proton Incorporation Reshapes Lattice Dynamics In BaSnO3‐Type Proton Conductors
Yttrium‐doped BaSnO3 exhibits isotope‐dependent changes in its low‐energy vibrational density of states upon hydration. Comparison of dry, H2O‐, and D2O‐treated samples re‐veals mass‐dependent phonon renormalization linked to proton dynamics near oxygen va‐cancies, providing experimental insight into hydrogen‐coupled lattice excitations in proton ...
Artur Braun +9 more
wiley +1 more source

