Results 231 to 240 of about 20,823 (293)

Nuclear Mechanotransduction Across the Metastatic Cascade: Decoding Spatiotemporal Heterogeneity in Cancer Dissemination

open access: yesAdvanced Science, EarlyView.
Tumor metastasis results from complex interactions between cancer cells and mechanical microenvironments. We propose a “nucleus‐centered, cross‐stage mechanical signal decoding” model, highlighting how nuclear mechanosensors interpret forces at different stages.
Linqi Song   +4 more
wiley   +1 more source

Self-locking and stiffening deployable tubular structures. [PDF]

open access: yesProc Natl Acad Sci U S A
Lee TU   +5 more
europepmc   +1 more source

Beyond Cartilage‐Inspired Supramolecular Polyurethane for Adaptive Impact‐Resistant Protection with Robustness, Self‐Healing, and Recyclability

open access: yesAdvanced Science, EarlyView.
Cartilage‐inspired supramolecular polyurethane–urea (PU‐BAMB) elastomers are developed by integrating hierarchical hydrogen bonding and π–π stacking interactions within a dynamically reconfigurable network. This synergistic supramolecular architecture overcomes the intrinsic trade‐off between rigidity and recoverability, imparting exceptional toughness,
Rou‐Han Lai   +14 more
wiley   +1 more source

Cells Dynamically Adapt Their Nuclear Volumes and Proliferation Rates During Single to Multicellular Transitions

open access: yesAdvanced Science, EarlyView.
It is currently not well understood how cells regulate basic properties, e.g., volume and mechanics within dense multicellular environments like tumors. Here, we show that different cell types of cancer and also normal cells largely decrease their nuclear and cellular volumes in emerging cell clusters and that this is partly driven by cell cycle shifts.
Vaibhav Mahajan   +13 more
wiley   +1 more source

Harnessing Phase Separation for the Development of High‐Performance Hydrogels

open access: yesAdvanced Science, EarlyView.
ABSTRACT Hydrogels are indispensable for the development of next‐generation bioelectronics, soft robotics, and biomedical devices, where their mechanical properties determine performance and reliability. Among strategies to enhance hydrogel mechanics, phase separation enables controlled heterogeneity resulting in gel networks that are reinforced by ...
Yue Shao   +3 more
wiley   +1 more source

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