Results 21 to 30 of about 382,415 (268)

Deformation and stiffness of spur gear teeth and their influence on gear noise [PDF]

open access: yesScientific Journal of Silesian University of Technology. Series Transport, 2015
Gear teeth are deformed due to the load. The deformation of gear teeth is causing some negative as well as positive effects. A tooth has a complex shape and due to the complex shape of the teeth, a theoretical determination of the deformation is ...
Silvia MEDVECKÁ-BEŇOVÁ
doaj  

Finite Element Modelling of Atomic Force Microscope Cantilever Beams with Uncertainty in Material and Dimensional Parameters

open access: yesEngineering Transactions, 2014
The stiffness and the natural frequencies of a rectangular and a V-shaped micro-cantilever beams used in Atomic Force Microscope (AFM) were analysed using the Finite Element (FE) method.
Bin WANG   +3 more
doaj   +1 more source

Biophysical approaches for studying viral entry

open access: yesFEBS Letters, EarlyView.
Viruses infect all living organisms and have been responsible for major epidemics and pandemics. Their ongoing evolutionary battle with host defenses creates a constant need for improved tools to study viral behavior. Advancing methods to probe viral attachment, fusion, and genome release deepen our understanding of how infections begin and support the
Inbar Yosibash, Raya Sorkin
wiley   +1 more source

Decoding the dynamic extracellular matrix in cancer—3D models and bioscaffolds rewire the rules of tumor progression

open access: yesFEBS Letters, EarlyView.
Cancer progression is regulated by the dynamic matrix code of the tumor microenvironment, which influences cellular behavior and disease development. Importantly, matrix remodeling in three‐dimensional cancer models more accurately reflects in vivo conditions compared to conventional two‐dimensional systems.
Sylvia Mangani   +3 more
wiley   +1 more source

Design and Simulation of a Titanium Alloy Lattice Bone Plate for 3D Printing

open access: yesShanghai Jiaotong Daxue xuebao, 2021
In order to improve the stress shielding effect caused by excessive elastic modulus of metal plates during fracture healing, a kind of 3D printing oriented lattice structure plate is designed based on topology optimization and the finite element modeling
ZHANG Cong   +4 more
doaj   +1 more source

Keratin 19 as a prognostic marker and contributing factor of metastasis and chemoresistance in high‐grade serous ovarian cancer

open access: yesMolecular Oncology, EarlyView.
Keratin 19 (KRT19) is overexpressed in high‐grade serous ovarian cancer with high levels of Kallikrein‐related peptidases (KLK) 4–7 and is associated with poor survival. In vivo analyses demonstrate that elevated KRT19 increases peritoneal tumour burden.
Sophia Bielesch   +13 more
wiley   +1 more source

Evaluation of Ultrasound Elastography Combined With Chi-Square Automatic Interactive Detector in Reducing Unnecessary Fine-Needle Aspiration on TIRADS 4 Thyroid Nodules

open access: yesFrontiers in Oncology, 2022
BackgroundConventional ultrasound diagnosis of thyroid nodules (TNs) had a high false-positive rate, resulting in many unnecessary fine-needle aspirations (FNAs).ObjectiveThis study aimed to establish a simple algorithm to reduce unnecessary FNA on ...
Xiao Liu   +5 more
doaj   +1 more source

Metastasis on pause: How dormant tumor cells stay hidden within the tumor microenvironment and evade immune surveillance

open access: yesMolecular Oncology, EarlyView.
Dormant cancer cells can hide in distant organs for years, evading treatment and the immune system. This review highlights how signals from the surrounding tissue and immune environment keep these cells inactive or trigger their reawakening. Understanding these mechanisms may help develop therapies to eliminate or control dormant cells and prevent ...
Kanishka Tiwary   +1 more
wiley   +1 more source

Sensitivity Analysis of Fastenings’ Types on Track\'s Life-Cycle [PDF]

open access: yesInternational Journal of Railway Research, 2014
During the study for the dimensioning as well as the selection of the individual materials constituting a  railway track, the ballast and the substructure present residual deformations, directly related to the  deterioration of the geometry of the track.
Konstantinos Giannakos
doaj  

Quantification of the stiffness and strength of cadherin ectodomain binding with different ions

open access: yesTheoretical and Applied Mechanics Letters, 2014
The stiffness and strength of extracellular (EC) region of cadherin are proposed to be two important mechanical properties both for cadherin as a mechanotransductor and for the formation of cell-cell adhesion.
Zhiyang Xu, Dechang Li, Ji Baohua
doaj   +1 more source

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