Results 31 to 40 of about 379,204 (219)

Theoretical Analysis and Experiment of the Five DOF Hybrid Robot P(RPR/RP)RR

IEEE Access
To meet the demands of machining new energy vehicles aluminum alloy structures, this paper introduced a five degree-of-freedom (DOF) hybrid robot, P(RPR/RP)RR, and conducted a systematic investigation into its kinematics, stiffness, and preliminary ...
Xuejian Ma, Xiaoyu He, Yundou Xu, Jiantao Yao, Yongsheng Zhao   +4 more
doaj   +1 more source

Hydrostatic pressure activates HIF‐1α via β‐catenin to promote stemness in breast cancer cells

FEBS Open Bio, EarlyView.
To mimic the elevated intestinal fluid pressure in breast cancers, we loaded human breast cancer cells (MCF‐7, MDA‐MB‐453, and BT‐474) to 50 mmHg hydrostatic pressure. Hydrostatic pressure exposure upregulated HIF‐1α and induced stemness in MCF‐7 and BT‐474 cells.
Da Zhai, Yong Xu, Jingjing Ma, Ratchanee Duangrat, Chen Yan, Jingyan Liang, Hua Wei, Bin Jiang, Tao‐Sheng Li   +8 more
wiley   +1 more source

Association Between Stiffness of the Deep Fibres of the Tibialis Anterior Muscle and Seiza Posture Performance After Ankle Fracture Surgery

Journal of Functional Morphology and Kinesiology
Background: Seiza, a traditional sitting posture requiring deep ankle plantarflexion and knee flexion, often becomes difficult after ankle fracture surgery because of restricted mobility.
Hayato Miyasaka, Bungo Ebihara, Takashi Fukaya, Koichi Iwai, Shigeki Kubota, Hirotaka Mutsuzaki   +5 more
doaj   +1 more source

Aquaporin‐3 and aquaporin‐5 impact the development of pancreatic ductal adenocarcinoma spheroids

FEBS Open Bio, EarlyView.
Schematic representation of the role of aquaporin‐3 (AQP3) and aquaporin‐5 (AQP5) in pancreatic ductal adenocarcinoma (PDAC). Both proteins are upregulated in PDAC and are associated with tumor progression and metastatic potential. Silencing AQP3 or AQP5 in PDAC spheroids results in decreased diameter, area, and overall growth, underscoring their key ...
Catarina Pimpão, Diogo M. Engrácia, Graça Soveral, Filipa Mendes   +3 more
wiley   +1 more source

Investigation failure behavior in the shear tensile test with variety of specimen stiffness [PDF]

MATEC Web of Conferences
This paper focuses on the failure behavior of clinched specimens with various stiffnesses under shear tensile loading. The primary objective is to assess the influence of the specimen stiffness with an arrangement of clinched joints.
Wolf Eugen, Brosius Alexander
doaj   +1 more source

Assessment of perinodular stiffness in differentiating malignant from benign thyroid nodules

Endocrine Connections, 2021
Objective: We evaluated the diagnostic accuracy of perinodular stiffness, four risk stratification systems (RSSs) (KWAK-TIRADS, ACR-TIRADS, EU-TIRADS, and C-TIRADS), and the combination of perinodular stiffness and the four RSSs in di fferentiating ...
Lei Hu, Xiao Liu, Chong Pei, Li Xie, Nianan He   +4 more
doaj   +1 more source

[18F]Fluorodeprenyl‐D2 PET as a Tool to Monitor Disease Activity in GAD65‐Ab Autoimmune Encephalitis

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective To evaluate [18F]fluorodeprenyl‐D2 ([18F]F‐DED) positron‐emission tomography (PET) imaging as a biomarker of disease activity in autoimmune encephalitis (AIE) associated with glutamic acid decarboxylase 65 (GAD65) antibodies. Methods [18F]F‐DED PET was performed in 25 GAD65‐AIE patients and 8 controls using dynamic (0–60 min) and ...
Julia S. Dorneich, Jonathan A. Gernert, Hanna Zimmermann, Lisa Tagnin, Marianthi Zeinaki, Laura Sanzo, Letizia Vogler, Elisabeth Kaufmann, Justina Dargvainiene, Frank Leypoldt, Gérard N. Bischof, Robert Perneczky, Boris‐Stephan Rauchmann, Simon Lindner, Günter U. Höglinger, Rudolf A. Werner, Martin Kerschensteiner, Tania Kümpfel, Matthias Brendel, Franziska S. Thaler   +19 more
wiley   +1 more source

Test for Crankcase Location Device of Locomotive and Vehicle

机车电传动, 2017
In order to test the crankcase location device of locomotive and vehicle systematically, the structure and principle was analyzed, and the two test scheme of single piece loading and system loading was designed and compared, focusing on research of ...
PENG Liqun, LIN Dawen, CHEN Gang, ZHOU Xuexiang, WANG Jin   +4 more
doaj  

The influence of “kickstand” screws on the mechanical performance of a lateral distal femoral plate: a finite element analysis

Bone & Joint Research
Aims: Lateral locked plating of distal femoral fractures is widely reported, yet there remains a 9% to 19% incidence of mechanical failure. Obliquely directed “kickstand screws”, from the metaphyseal portion of a plate toward far-sided articular ...
Alex Trompeter, Alexis Christen, Claus Gerber, Bernhard Hofstaetter, Felix Wipf, Jason Lowe   +5 more
doaj   +1 more source

GAD65 Antibody ELISA With Extended Reportable Range: Validation and Guidance for Neurological Practice

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective To (1) validate GAD65‐ELISA detection and quantification for type 1 diabetes mellitus and autoimmune neurological diagnoses, (2) correlate ELISA results (reference range < 5 IU/mL) with established radioimmunoprecipitation assay (RIA; ≤ 0.02 nmol/L), and (3) define ELISA clinical utility and pitfalls.
Andrew McKeon, Dana Olofson, Diana Anissian, Divyanshu Dubey, Eoin P. Flanagan, Max C. Herman, Sarosh R. Irani, Daniel H. Lachance, Maria A. Willrich, Sean Pittock, John R. Mills, Anastasia Zekeridou   +11 more
wiley   +1 more source