Results 31 to 40 of about 1,102,264 (299)

Deformation and stiffness of spur gear teeth and their influence on gear noise [PDF]

open access: yesScientific Journal of Silesian University of Technology. Series Transport, 2015
Gear teeth are deformed due to the load. The deformation of gear teeth is causing some negative as well as positive effects. A tooth has a complex shape and due to the complex shape of the teeth, a theoretical determination of the deformation is ...
Silvia MEDVECKÁ-BEŇOVÁ
doaj  

Stiffness modeling of robotic manipulator with gravity compensator [PDF]

open access: yes, 2013
The paper focuses on the stiffness modeling of robotic manipulators with gravity compensators. The main attention is paid to the development of the stiffness model of a spring-based compensator located between sequential links of a serial structure.
B-J Yi   +6 more
core   +4 more sources

COMP–PMEPA1 axis promotes epithelial‐to‐mesenchymal transition in breast cancer cells

open access: yesMolecular Oncology, EarlyView.
This study reveals that cartilage oligomeric matrix protein (COMP) promotes epithelial‐to‐mesenchymal transition (EMT) in breast cancer. We identify PMEPA1 (protein TMEPAI) as a novel COMP‐binding partner that mediates EMT via binding to the TSP domains of COMP, establishing the COMP–PMEPA1 axis as a key EMT driver in breast cancer.
Konstantinos S. Papadakos   +6 more
wiley   +1 more source

Finite Element Modelling of Atomic Force Microscope Cantilever Beams with Uncertainty in Material and Dimensional Parameters

open access: yesEngineering Transactions, 2014
The stiffness and the natural frequencies of a rectangular and a V-shaped micro-cantilever beams used in Atomic Force Microscope (AFM) were analysed using the Finite Element (FE) method.
Bin WANG   +3 more
doaj   +1 more source

Modeling and design of energy efficient variable stiffness actuators [PDF]

open access: yes, 2010
In this paper, we provide a port-based mathematical framework for analyzing and modeling variable stiffness actuators. The framework provides important insights in the energy requirements and, therefore, it is an important tool for the design of energy ...
Carloni, R.   +3 more
core   +2 more sources

Stiff Arteries, Stiff Ventricles [PDF]

open access: yesCirculation: Cardiovascular Imaging, 2016
The biophysical properties and neurohormonal regulation of arterial function are influential mediators of cardiovascular disease. Over the past 3 decades, the prognostic importance of arterial stiffness, as a measurable indicator of arterial function, has been recognized in both unselected populations and among patients with cardiovascular risk factors.
openaire   +4 more sources

Keratin 19 as a prognostic marker and contributing factor of metastasis and chemoresistance in high‐grade serous ovarian cancer

open access: yesMolecular Oncology, EarlyView.
Keratin 19 (KRT19) is overexpressed in high‐grade serous ovarian cancer with high levels of Kallikrein‐related peptidases (KLK) 4–7 and is associated with poor survival. In vivo analyses demonstrate that elevated KRT19 increases peritoneal tumour burden.
Sophia Bielesch   +13 more
wiley   +1 more source

Comparison of Three Stiffness Testers [PDF]

open access: yes, 1951
Stiffness is defined and some of the factors affecting stiffness are given. Also, the underlying principles upon which most stiffness testers are based are given. Three of the commonly used stiffness instruments are used for this comparison study.
Anderson, Arne H.
core   +1 more source

Reversal of aging-induced increases in aortic stiffness by targeting cytoskeletal protein-protein interfaces [PDF]

open access: yes, 2018
Background: The proximal aorta normally functions as a critical shock absorber that protects small downstream vessels from damage by pressure and flow pulsatility generated by the heart during systole.
AortaGen Consortium, the   +20 more
core   +2 more sources

Hippo pathway at the crossroads of stemness and therapeutic resistance in breast cancer

open access: yesMolecular Oncology, EarlyView.
Dysregulation of the Hippo pathway drives nuclear accumulation of YAP/TAZ, activating stemness‐related transcriptional programs that sustain breast cancer stemness and fuel therapeutic resistance across subtypes, underscoring Hippo signaling as a targetable vulnerability. Figure created and edited with BioRender.com.
Giulia Schiavoni   +11 more
wiley   +1 more source

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