Results 51 to 60 of about 1,102,264 (299)

Age‐Related Characteristics of SYT1‐Associated Neurodevelopmental Disorder

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objectives We describe the clinical manifestations and developmental abilities of individuals with SYT1‐associated neurodevelopmental disorder (Baker‐Gordon syndrome) from infancy to adulthood. We further describe the neuroradiological and electrophysiological characteristics of the condition at different ages, and explore the associations ...
Sam G. Norwitz, Josefine Eck, Joel S. Winston, Kate Baker   +3 more
wiley   +1 more source

Stiffness and mass matrices for shells of revolution (SAMMSOR II) [PDF]

, 1974
Utilizing element properties, structural stiffness and mass matrices are generated for as many as twenty harmonics and stored on magnetic tape. Matrices generated constitute input data to be used by other stiffness of revolution programs.
Haisler, W. E., Tillerson, J. R.
core   +1 more source

A 73‐Year‐Old Man With Several Years of Difficulty Climbing Stairs and Frequent Tripping

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT A 73‐year‐old man presented with progressive weakness and atrophy predominantly affecting the distal finger flexors and quadriceps muscles. Electrophysiological studies demonstrated mixed myogenic and neurogenic features. Muscle MRI showed inflammatory changes, and muscle biopsy revealed granulomatous myositis with histologic features ...
Mehmet Can Sari, Arens Taga, Sonya Ulrike Steele, Ahmet Hoke   +3 more
wiley   +1 more source

Theoretical Analysis and Experiment of the Five DOF Hybrid Robot P(RPR/RP)RR

IEEE Access
To meet the demands of machining new energy vehicles aluminum alloy structures, this paper introduced a five degree-of-freedom (DOF) hybrid robot, P(RPR/RP)RR, and conducted a systematic investigation into its kinematics, stiffness, and preliminary ...
Xuejian Ma, Xiaoyu He, Yundou Xu, Jiantao Yao, Yongsheng Zhao   +4 more
doaj   +1 more source

Ketogenic Diet as an Epigenetic Therapy in SETD1B‐Related Epilepsy

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Histone lysine methyltransferases such as SETD1B regulate chromatin structure and gene transcription. Ketone bodies, including butyrate, act as histone deacetylase inhibitors. We report a 4‐year‐old boy with SETD1B‐related absence epilepsy, refractory to conventional medications, who achieved sustained > 90% seizure reduction on the Modified ...
Erica Tsang, Brian S. Gloss, Jessica P. Hayes, Andrew J. A. Holland, Manoj P. Menezes, Joceline A. Branson, Shekeeb S. Mohammad, Jingya J. Yan, Shrujna Patel, Velda X. Han, Russell C. Dale   +10 more
wiley   +1 more source

Stiffness Analysis Of Multi-Chain Parallel Robotic Systems [PDF]

, 2009
The paper presents a new stiffness modelling method for multi-chain parallel robotic manipulators with flexible links and compliant actuating joints. In contrast to other works, the method involves a FEA-based link stiffness evaluation and employs a new ...
Chablat, Damien, Klimchik, Alexandr, Pashkevich, Anatoly, Wenger, Philippe   +3 more
core   +3 more sources

[18F]Fluorodeprenyl‐D2 PET as a Tool to Monitor Disease Activity in GAD65‐Ab Autoimmune Encephalitis

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective To evaluate [18F]fluorodeprenyl‐D2 ([18F]F‐DED) positron‐emission tomography (PET) imaging as a biomarker of disease activity in autoimmune encephalitis (AIE) associated with glutamic acid decarboxylase 65 (GAD65) antibodies. Methods [18F]F‐DED PET was performed in 25 GAD65‐AIE patients and 8 controls using dynamic (0–60 min) and ...
Julia S. Dorneich, Jonathan A. Gernert, Hanna Zimmermann, Lisa Tagnin, Marianthi Zeinaki, Laura Sanzo, Letizia Vogler, Elisabeth Kaufmann, Justina Dargvainiene, Frank Leypoldt, Gérard N. Bischof, Robert Perneczky, Boris‐Stephan Rauchmann, Simon Lindner, Günter U. Höglinger, Rudolf A. Werner, Martin Kerschensteiner, Tania Kümpfel, Matthias Brendel, Franziska S. Thaler   +19 more
wiley   +1 more source

Association Between Stiffness of the Deep Fibres of the Tibialis Anterior Muscle and Seiza Posture Performance After Ankle Fracture Surgery

Journal of Functional Morphology and Kinesiology
Background: Seiza, a traditional sitting posture requiring deep ankle plantarflexion and knee flexion, often becomes difficult after ankle fracture surgery because of restricted mobility.
Hayato Miyasaka, Bungo Ebihara, Takashi Fukaya, Koichi Iwai, Shigeki Kubota, Hirotaka Mutsuzaki   +5 more
doaj   +1 more source

Consideration of the restriction of lateral contraction in the elastic behaviour of cohesive zone models

, 2015
Cohesive zone models do not consider the lateral contraction of adhesive layers under tensile loads. The constraint of the lateral contraction by the adherents which depends on the geometry of the adhesive layer has a major influence on the normal ...
Hesebeck, Olaf
core   +1 more source

Assessing the Role of Longitudinal Variability of Vertical Track Stiffness in the Long-Term Deterioration [PDF]

, 2016
The performance of the railway system in terms of dynamic loading is depending mainly on the track support conditions. Usually, the track stiffness is used as the main parameter to describe the support conditions and is defined as the ratio of the load ...
Bezin, Yann, Grossoni, Ilaria, Ramos Andrade, Antonio   +2 more
core   +1 more source