Results 51 to 60 of about 1,723,107 (335)

Genetic attenuation of ALDH1A1 increases metastatic potential and aggressiveness in colorectal cancer

open access: yesMolecular Oncology, EarlyView.
Aldehyde dehydrogenase 1A1 (ALDH1A1) is a cancer stem cell marker in several malignancies. We established a novel epithelial cell line from rectal adenocarcinoma with unique overexpression of this enzyme. Genetic attenuation of ALDH1A1 led to increased invasive capacity and metastatic potential, the inhibition of proliferation activity, and ultimately ...
Martina Poturnajova   +25 more
wiley   +1 more source

Finite Element Modelling of Atomic Force Microscope Cantilever Beams with Uncertainty in Material and Dimensional Parameters

open access: yesEngineering Transactions, 2014
The stiffness and the natural frequencies of a rectangular and a V-shaped micro-cantilever beams used in Atomic Force Microscope (AFM) were analysed using the Finite Element (FE) method.
Bin WANG   +3 more
doaj   +1 more source

Comparison of Three Stiffness Testers [PDF]

open access: yes, 1951
Stiffness is defined and some of the factors affecting stiffness are given. Also, the underlying principles upon which most stiffness testers are based are given. Three of the commonly used stiffness instruments are used for this comparison study.
Anderson, Arne H.
core   +1 more source

RIPK4 function interferes with melanoma cell adhesion and metastasis

open access: yesMolecular Oncology, EarlyView.
RIPK4 promotes melanoma growth and spread. RIPK4 levels increase as skin lesions progress to melanoma. CRISPR/Cas9‐mediated deletion of RIPK4 causes melanoma cells to form less compact spheroids, reduces their migratory and invasive abilities and limits tumour growth and dissemination in mouse models.
Norbert Wronski   +9 more
wiley   +1 more source

Dependence of the Spin Transfer Torque Switching Current Density on the Exchange Stiffness Constant

open access: yes, 2012
We investigate the dependence of the switching current density on the exchange stiffness constant in the spin transfer torque magnetic tunneling junction structure with micromagnetic simulations.
You, Chun-Yeol
core   +1 more source

COMP–PMEPA1 axis promotes epithelial‐to‐mesenchymal transition in breast cancer cells

open access: yesMolecular Oncology, EarlyView.
This study reveals that cartilage oligomeric matrix protein (COMP) promotes epithelial‐to‐mesenchymal transition (EMT) in breast cancer. We identify PMEPA1 (protein TMEPAI) as a novel COMP‐binding partner that mediates EMT via binding to the TSP domains of COMP, establishing the COMP–PMEPA1 axis as a key EMT driver in breast cancer.
Konstantinos S. Papadakos   +6 more
wiley   +1 more source

Design and Simulation of a Titanium Alloy Lattice Bone Plate for 3D Printing

open access: yesShanghai Jiaotong Daxue xuebao, 2021
In order to improve the stress shielding effect caused by excessive elastic modulus of metal plates during fracture healing, a kind of 3D printing oriented lattice structure plate is designed based on topology optimization and the finite element modeling
ZHANG Cong   +4 more
doaj   +1 more source

Stiffness and mass matrices for shells of revolution (SAMMSOR II) [PDF]

open access: yes, 1974
Utilizing element properties, structural stiffness and mass matrices are generated for as many as twenty harmonics and stored on magnetic tape. Matrices generated constitute input data to be used by other stiffness of revolution programs.
Haisler, W. E., Tillerson, J. R.
core   +1 more source

An intelligent hammer: a novel concept for automating nail and pile driving [PDF]

open access: yes, 2005
Some interesting novel ideas on how the compliance needs of manipulators may be met by changing the stiffness of a structure have been presented in a paper by Ang and Andeen [1].
Ilanko, Sinniah
core   +3 more sources

Arterial Stiffness and Hypertension in the Elderly

open access: yesFrontiers in Cardiovascular Medicine, 2020
Hypertension prevalence increases with age. Age and high blood pressure are the two main determinants of arterial stiffness. In elderly hypertensives, large arteries stiffen and systolic and pulse pressures increase, due to wave reflections.
S. Laurent, P. Boutouyrie
semanticscholar   +1 more source

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