Results 41 to 50 of about 1,391,136 (279)

L‐aspartate oxidase provides new insights into fumarate reduction in anaerobic darkness in Synechocystis sp. PCC6803

open access: yesFEBS Letters, EarlyView.
Synechocystis strains deficient in succinate dehydrogenase (SDH) secrete more succinate than the WT under dark anaerobic conditions, supporting that SDH then primarily acts as SDH, not as a fumarate reductase. L‐aspartate oxidase (Laspo) from Synechocystis is functional under anaerobic conditions, reducing fumarate to succinate.
Kateryna Kukil   +3 more
wiley   +1 more source

Stifle Joint Rotational Variation in Extended Stifles in Healthy Dogs Undergoing Computed Tomography Examinations

open access: yes, 2020
OBJECTIVES:  The aim of this study was to evaluate stifle joint rotational stability in response to body position and repositioning in dogs undergoing computed tomography (CT).MATERIALS AND METHODS:  Nine dogs (18 stifles) with no history or clinical ...
Buelund, Lene E   +3 more
core   +1 more source

Membrane composition and thermodynamic identity as boundaries of life for synthetic cell research

open access: yesFEBS Letters, EarlyView.
What makes a cell a cell? The boundary of a living cell is not just a wall. Read as a Markov blanket, the membrane separates internal from external states, generating identity and non‐equilibrium order. Can this identity be rebuilt from scratch in a synthetic cell?
Caterina Presutti, Bert Poolman
wiley   +1 more source

Effect of anesthetizing individual compartments of the stifle joint in horses with experimentally induced stifle joint lameness

open access: yesAmerican Journal of Veterinary Research, 2014
Abstract Objective—To evaluate the effects of sequential anesthesia of the individual compartments of the equine stifle joint on lameness induced by intra-articular deposition of interleukin (IL)-1β. Animals—6 horses. Procedures—For each horse, baseline hind limb lameness was first evaluated.
Ferenc, Tóth   +3 more
openaire   +2 more sources

Radiographic risk factors for contralateral rupture in dogs with unilateral cranial cruciate ligament rupture. [PDF]

open access: yesPLoS ONE, 2014
Complete cranial cruciate ligament rupture (CR) is a common cause of pelvic limb lameness in dogs. Dogs with unilateral CR often develop contralateral CR over time.
Connie Chuang   +7 more
doaj   +1 more source

Epigenetic heterogeneity and plasticity in therapy‐induced tumor states through single‐cell multi‐omics

open access: yesMolecular Oncology, EarlyView.
Single‐cell multi‐omics reveals epigenetic heterogeneity across therapy‐adaptive tumor states, including quiescent/dormant, drug‐tolerant persister, and EMT‐like phenotypes. By linking regulatory features with state‐associated biomarkers, these approaches inform biomarker‐guided therapeutic strategies for evolving tumors.
Hee Jung Kim   +3 more
wiley   +1 more source

Single‐cell DNA methylation profiling: Technologies, computation, and applications in precision oncology

open access: yesMolecular Oncology, EarlyView.
Single‐cell DNA methylation (scDNAme) profiling maps epimutational clonal evolution, revealing mechanisms of malignancy and therapeutic resistance across diverse cancer types. By providing a high‐resolution landscape of intratumoral heterogeneity, these technologies empower precise patient stratification, guide the development of enhanced ...
Ik Soo Kim
wiley   +1 more source

Spatial biology in cancer epigenetics

open access: yesMolecular Oncology, EarlyView.
Spatial epigenomics combines molecular profiling with tissue architecture to reveal how gene regulation is organized within intact tissues. In cancer, these technologies uncover the mechanisms driving tumor heterogeneity and microenvironmental interactions, opening new opportunities for biomarker discovery and precision medicine.
Eva Crespo‐García, Manel Esteller
wiley   +1 more source

Traumatic Disease of the Stifle Joint [PDF]

open access: yesJournal of Comparative Pathology and Therapeutics, 1898
n ...
openaire   +2 more sources

Arthroscopic Findings Following Experimental Cranial Cruciate Ligament Desmotomy in Dog [PDF]

open access: yesIranian Journal of Veterinary Surgery, 2006
Objective- Using the arthroscopic surgery technique for experimental transection of cranial cruciate ligament and arthroscopic findings of stifle joint following ligament transection. Design- Experimental study.
Kamran Sardari   +2 more
doaj  

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