Results 51 to 60 of about 5,631 (285)

Arthroscopic assessment of stifle synovitis in dogs with cranial cruciate ligament rupture. [PDF]

PLoS ONE, 2014
Cranial cruciate ligament rupture (CR) is a degenerative condition in dogs that typically has a non-contact mechanism. Subsequent contralateral rupture often develops in dogs with unilateral CR.
Jeffrey P Little, Jason A Bleedorn, Brian J Sutherland, Ruth Sullivan, Vicki L Kalscheur, Megan A Ramaker, Susan L Schaefer, Zhengling Hao, Peter Muir   +8 more
doaj   +1 more source

Quantifying the Impact of Ocrelizumab on Paramagnetic Rim Lesions in Multiple Sclerosis

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Paramagnetic rim lesions (PRLs) are a subset of chronic active multiple sclerosis (MS) lesions marked by iron‐laden microglia and macrophages. Ocrelizumab, a monoclonal antibody targeting CD20+ B cells, suppresses acute MS activity, but its effect on PRLs remains unclear. In a longitudinal study of 29 ocrelizumab‐treated patients with at least
Kimberly H. Markowitz, Neha V. Safi, Iliana Pliska‐Bloch, Ulrike W. Kaunzner, Ha Luu, Mert Sisman, Yi Wang, Thanh D. Nguyen, Sandra Hurtado Rúa, Susan A. Gauthier   +9 more
wiley   +1 more source

Arthroscopic Findings Following Experimental Cranial Cruciate Ligament Desmotomy in Dog [PDF]

Iranian Journal of Veterinary Surgery, 2006
Objective- Using the arthroscopic surgery technique for experimental transection of cranial cruciate ligament and arthroscopic findings of stifle joint following ligament transection. Design- Experimental study.
Kamran Sardari, Ahmadreza Raji, Nazanin Farazan   +2 more
doaj  

Early Clinical, Imaging, and Pathological Characteristics of SRPK3/TTN‐Digenic Myopathy

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective SRPK3/TTN‐digenic myopathy was recently established as a skeletal muscle myopathy caused by digenic inheritance. This study characterizes the early clinical presentation of SRPK3/TTN‐digenic myopathy in one previously reported and seven newly identified pediatric patients.
Rotem Orbach, Sandra Donkervoort, Carola Hedberg‐Oldfors, Giovanni Baranello, Dimah Saade, Precilla D'Souza, Ruchee Patel, Eva Michael, A. Reghan Foley, Diana Bharucha‐Goebel, S. Jin Haugland, Meghan McAnally, Omer Abdul Hamid, Katherine Chao, Ellen F. Macnamara, Alan H. Beggs, Anna Sarkozy, Juliane Mueller, Steven A. Moore, Richard S. Finkel, Cynthia J. Tifft, Francesco Muntoni, Anders Oldfors, Carsten G. Bönnemann   +23 more
wiley   +1 more source

A 17 Year Old With Developmental Delay Presenting With Increasing Confusion and Imbalance

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Methylmalonic acidemia is an autosomal recessive genetic disorder primarily caused by defects in methylmalonyl‐CoA mutase and cobalamin (vitamin B12) metabolism. These defects disrupt the tricarboxylic acid cycle and oxidative phosphorylation, leading to the abnormal accumulation of metabolic products such as methylmalonic acid, propionic acid,
Wei Zhao, Yingli Zhang, Hongliang Zheng
wiley   +1 more source

Characterization of intra-articular dose administration in the stifle joint of rabbits for toxicity testing

, 2017
Intra-articular administration is a standard therapeutic option for patients with rheumatoid arthritis, and pharmaceutical companies are increasing the research and development of injectable treatments.
Yasoshima, Kayo, Brown, Alan, Saravanan, Chandrassegar, Gao, Jiaping, Devine, Pj, Barnes, David, Yamada, Ken, Magnifico, Maria, Beaulieu, Valerie, Ma, Margaret   +9 more
core   +1 more source

Quantification of three-dimensional soft tissue artifacts in the canine hindlimb during passive stifle motion

BMC Veterinary Research, 2018
Background Three-dimensional joint kinematics during canine locomotion are commonly measured using skin marker-based stereophotogrammetry technologies.
Cheng-Chung Lin, Chia-Lin Chang, Ming Lu, Tung-Wu Lu, Ching-Ho Wu   +4 more
doaj   +1 more source

Association Between Symptomatic Knee Osteoarthritis and Target Glycemic Control in Individuals With Type 2 Diabetes

Arthritis Care &Research, EarlyView.
Objective Knee osteoarthritis (OA) commonly affects individuals with type 2 diabetes (T2DM) and is associated with increased risk of diabetes‐related complications. To better understand potential mechanisms, we examined the association between symptomatic knee OA and glycemic control in individuals with T2DM.
Lauren K. King, Alanna Weisman, Baiju R. Shah, Robert Goldberg, Amish Parikh, Ian Stanaitis, Vivian Hung, Rosane Nisenbaum, Abdalmohsen Almodahka, Lorraine Lipscombe, Gillian A. Hawker   +10 more
wiley   +1 more source

Associations of Sleep and Shift Work With Osteoarthritis Risk

Arthritis Care &Research, EarlyView.
Objective Daily rhythms may be critical for maintaining homeostasis of joint tissues. We aimed to investigate the relationships among circadian clock disruption, sleep, and osteoarthritis (OA) risk in humans. Methods In the UK Biobank, a prospective 500,000–person cohort, we evaluated associations among sleep duration, sleeplessness/insomnia, and shift
Elizabeth L. Yanik, Abigail Bridgeman, Erik D. Herzog, Vy Pham, Bradley A. Evanoff, Farshid Guilak   +5 more
wiley   +1 more source

Effect of Bipolar Radiofrequency Energy on Canine Stifle Joint Fluid Temperature

, 2018
Objective The aim of this study was to evaluate the effect of bipolar radiofrequency (RF) energy on canine stifle joint fluid temperature. Materials and Methods A standard stifle arthroscopy was performed on 15 canine large breed
Cindy Shmon, Cheryl Waldner, Suresh Sathya, Koji Aoki   +3 more
core   +1 more source