Results 51 to 60 of about 48,106 (292)

DDX3X induces mesenchymal transition of endothelial cells by disrupting BMPR2 signaling

FEBS Open Bio, EarlyView.
Elevated DDX3X expression led to downregulation of BMPR2, a key regulator of endothelial homeostasis and function. Our co‐immunoprecipitation assays further demonstrated a molecular interaction between DDX3X and BMPR2. Notably, DDX3X promoted lysosomal degradation of BMPR2, thereby impairing its downstream signaling and facilitating endothelial‐to ...
Yu Zhang, Jing Wang, De‐Hui Qian, Yang‐Fan Lv, Tian‐Le Cheng, Da‐Peng Wang, Jing Zhang, Ye Fan   +7 more
wiley   +1 more source

Osteocondrose de articulação fêmoro-tíbio-patelar em potro da raça Crioula Stifle joint osteochondrosis in a Criollo foal

Ciência Rural, 2008
Um potro da raça crioula, com dois anos de idade, foi encaminhado ao Hospital Veterinário da Universidade Federal de Santa Maria (UFSM) apresentando aumento de volume na região da patela esquerda e claudicação manifestada ao trote.
Andressa Bueno, Jordana Beal, Luiz Sergio Segala de Oliveira, Flávio Desessards De La Corte   +3 more
doaj   +1 more source

Ex vivo biomechanical evaluation of extracapsular stabilization with quasi-isometric points in canine cranial cruciate ligament-deficient stifles

BMC Veterinary Research, 2023
Background Cranial cruciate ligament (CCL) disease is one of the most common causes of lameness in dogs. The extracapsular stabilization (ECS) utilizing bone anchors and monofilament nylon leader was an alternative treatment for CCL-deficient (CCLD) dogs.
Wei-Ru Hsu, Cheng-Chung Lin, Cheng-Yuan Sun, Ching-Ho Wu   +3 more
doaj   +1 more source

Management of Candida guilliermondii joint infection in a dog [PDF]

, 2015
Background: Candida spp. are dimorphic fungi in the family Cryptococcaceae. Infections with Candida spp. are usually rare conditions in dogs, but immunocompromised patients have a higher risk for developing invasive candidal infections. Case presentation:
Alberto Crovace, Antonello Bufalari, Chiara Maggio, Fabrizio Passamonti, Giulia Moretti, Reinhard Konrad Straubinger, Valentina Stefanetti   +6 more
core   +1 more source

FGFR Like1 drives esophageal cancer progression via EMT, PI3K/Akt, and notch signalling: insights from clinical data and next‐generation sequencing analysis

FEBS Open Bio, EarlyView.
Clinical analysis reveals significant dysregulation of FGFRL1 in esophageal cancer (EC) patients. RNAi‐coupled next‐generation sequencing (NGS) and in vitro study reveal FGFRL1‐mediated EC progression via EMT, PI3K/Akt, and Notch pathways. Functional assays confirm its role in tumor growth, migration, and invasion.
Aprajita Srivastava, Anoop Saraya, Deepak Gunjan, Rinu Sharma   +3 more
wiley   +1 more source

Follow the Crowd in a New Direction: When Conformity Pressure Facilitates Group Creativity (And When It Does Not) [PDF]

, 2011
Adopting a person by situation interaction approach, we identified conditions under which conformity pressure can either stifle or boost group creativity depending on the joint effects of norm content and group personality composition.
Duguid, Michelle M, Goncalo, Jack
core   +1 more source

SNUPN‐Related Muscular Dystrophy: Novel Phenotypic, Pathological and Functional Protein Insights

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective SNUPN‐related muscular dystrophy or LGMDR29 is a new entity that covers from a congenital or childhood onset pure muscular dystrophy to more complex phenotypes combining neurodevelopmental features, cataracts, or spinocerebellar ataxia. So far, 12 different variants have been described.
Nuria Muelas, Pablo Iruzubieta, Alberto Damborenea, Laura Pérez‐Fernández, Inmaculada Azorín, Juan Carlos Jiménez García, Ana Töpf, Pilar Martí, Lorena Fores‐Toribio, María Manterola, Rosana Blanco‐Mañez, Oihane Pikatza‐Menoio, Sonia Alonso‐Martín, Volker Straub, Aitziber L. Cortajarena, Adolfo López de Munain, David De Sancho, Lorea Blázquez, Juan J. Vilchez   +18 more
wiley   +1 more source

Development of a Canine Rigid Body Musculoskeletal Computer Model to Evaluate Gait

Frontiers in Bioengineering and Biotechnology, 2020
BackgroundKinematic and kinetic analysis have been used to gain an understanding of canine movement and joint loading during gait. By non-invasively predicting muscle activation patterns and forces during gait, musculoskeletal models can further our ...
Nathan P. Brown, Gina E. Bertocci, Gregory J. R. States, Gwendolyn J. Levine, Jonathan M. Levine, Dena R. Howland, Dena R. Howland, Dena R. Howland   +7 more
doaj   +1 more source

Therapeutic ultrasound as an aid in tibial fracture management in a dog [PDF]

, 2017
A six-year-old, male, neutered Bernese mountain dog was presented with acute left hind limb lameness. Based on the symptoms, orthopedic examination and radiographic evaluation, a cranial cruciate ligament rupture was diagnosed.
de Bakker, Evelien, Heremans, Jana, Samoy, Yves, Van Ryssen, Bernadette   +3 more
core   +1 more source

Chronological and Spatial Distribution of Skeletal Muscle Fat Replacement in FHL1‐Related Myopathies

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objectives Variants in the FHL1 gene cause FHL1‐related myopathies (FHL1‐RMs), a group of neuromuscular disorders with diverse clinical presentations. This study aimed to comprehensively characterize the spatial and temporal patterns of skeletal muscle fat replacement throughout the whole body in FHL1‐RMs, to examine disease progression over ...
Rui Shimazaki, Satoru Noguchi, Hotake Takizawa, Yasushi Oya, Yuji Takahashi, Hirofumi Komaki, Hajime Arahata, Shinichiro Hayashi, Ichizo Nishino   +8 more
wiley   +1 more source