Results 31 to 40 of about 52,163 (263)

The experience of stillbirth [PDF]

Journal of Reproductive and Infant Psychology, 2017
Stillbirth has a significant impact on parents, health professionals and wider society and yet related research, policy and practice remains low-profile internationally.
openaire   +3 more sources

Research priorities for stillbirth in Australia: outcomes of a national priority setting partnership

BMC Pregnancy and Childbirth
Background Stillbirth research priorities for Australia were identified in 2015. A renewed priority setting exercise identified current research priorities to address the national burden of stillbirth.
Kirstin Tindal, Fran Boyle, Christine Andrews, Chrissie Astell, Jane Yelland, Sarah McIntyre, Bec Jenkinson, Sean Seeho, Miranda Davies-Tuck, Deanna Stuart-Butler, Philipa Middleton, David Ellwood, Adrienne Gordon, Vicki Flenady   +13 more
doaj   +1 more source

Incidence and sociodemographic, living environment and maternal health associations with stillbirth in a tertiary healthcare setting in Kano, Northern Nigeria

BMC Pregnancy and Childbirth, 2022
Background Almost two million stillbirths occur annually, most occurring in low- and middle-income countries. Nigeria is reported to have one of the highest stillbirth rates on the African continent.
Rebecca Milton, F. Modibbo, D. Gillespie, F. I. Alkali, A. S. Mukaddas, A. Kassim, F. H. Sa’ad, F. M. Tukur, R. Y. Khalid, M. Y. Muhammad, M. Bello, C. P. Edwin, E. Ogudo, K. C. Iregbu, L. Jones, K. Hood, P. Ghazal, J. Sanders, B. Hassan, F. J. Belga, T. R. Walsh   +20 more
doaj   +1 more source

NICE: A Two‐Step Non‐Invasive Framework for Embryo cfDNA Read Enrichment and Quality Assessment

Advanced Science, EarlyView.
The non‐invasive NICE framework, built on an ensemble stacking machine learning model, prioritizes embryos by analyzing cell‐free DNA from spent culture medium. By integrating multimodal signals, including genomic and epigenetic profiles, this automated approach standardizes morphological assessment without human bias, paving the way for more precise ...
Xueya Zhou, Shu Ding, Zhenyi Zhang, Qiaoling Shangguan, Jie Qiao, Peijie Zhou, Yidong Chen   +6 more
wiley   +1 more source

Iodine and thyroid status during pregnancy and risk of stillbirth: A population‐based nested case–control study

Maternal and Child Nutrition, 2022
Prior research suggests that severe iodine deficiency in pregnancy may be associated with stillbirth. However, the relationship between mild to moderate iodine insufficiency, which is prevalent even in developed countries, and risk of stillbirth is ...
Alexandra C. Purdue‐Smithe, Tuija Männistö, Elijah Reische, Kurunthachalam Kannan, Un‐Jung Kim, Eila Suvanto, Heljä‐Marja Surcel, Mika Gissler, James L. Mills   +8 more
doaj   +1 more source

An Injectable ROS‐Responsive Nanozyme Hydrogel Regulates the Uterine Microenvironment to Prevent Intrauterine Adhesions

Advanced Science, EarlyView.
The injectable CeTA@GPP hydrogel is administered via intrauterine injection, forming a protective barrier. In the high ROS inflammatory microenvironment of injured endometrium, boronate ester cleavage triggers responsive CeTA release and local enrichment.
Peixian Cheng, Jian Song, Yuxin Li, Ming Chen, Zeshen Liang, Binyao Qiu, Xuemin Liu, Xuetao Shi, Yong Fan   +8 more
wiley   +1 more source

Understanding enablers and barriers to implementing the Safer Baby Bundle: a mixed-methods study with site leads

BMC Health Services Research
Background The Australian Safer Baby Bundle (SBB) consists of five elements (smoking cessation, fetal growth restriction, decreased fetal movements, maternal side sleeping and decision making around timing of birth) which aim to reduce stillbirth and ...
Christine Andrews, Fran Boyle, Ashley Pade, Ann Lancaster, Philippa Middleton, David Ellwood, Adrienne Gordon, Michael Nicholl, Kirstine Sketcher-Baker, Tanya Farrell, Ida Stevia Diget, Vicki Flenady   +11 more
doaj   +1 more source

NSUN2‐Mediated m5C Modification of TGFB1 in Trophoblasts Remodels Macrophage Function to Prevent URSA

Advanced Science, EarlyView.
NSUN2 and m5C decline in URSA villous tissues. Trophoblast Nsun2 ablation disrupts macrophage‐mediated maternal‐fetal tolerance and triggers embryo resorption. Mechanistically, NSUN2‐YBX1 axis stabilizes m5C‐modified TGFB1 mRNA to maintain TGF‐β1 secretion and M2 polarization, and restoring this signaling rescues maternal‐fetal immune tolerance to ...
Xiaoxiao Zhu, Xinkui Liu, Xiaoyan Yu, Qiaoqiao Han, Feifei Shi, Weiwei Song, Lu Liu, Chu Chu, Chenyang Shen, Zhen Zhang, Xia Li   +10 more
wiley   +1 more source

SAV1 in Cooperation With FKBP52 Participates in Implantation

Advanced Science, EarlyView.
The MST‐SAV1 complex modulates FKBP52 phosphorylation to fine‐tune PR activity, ensuring timely uterine transition to receptivity under estrogen signaling for implantation. Stromal SAV1 scaffolds MST1/2‐mediated FKBP52 phosphorylation via noncanonical Hippo to promote PR activity.
Yuhan Shao, Yafang Lu, Zhaoyu Jia, Junxiang Ren, Ziyi Ge, Xinyu Liu, Hui Zhao, Zi‐Jiang Chen, Junhao Yan, Wei Wang, Jia Yuan   +10 more
wiley   +1 more source

CHD8‐Dependent Chromatin Licensing Sustains Trophoblast Stem Cell Transcriptional Programs

Advanced Science, EarlyView.
In this study, Huang et al., identify chromatin remodeler CHD8 as an essential factor in TSC maintenance and placental development. CHD8‐dependent chromatin accessibility supports the occupancy of key trophoblast TFs and is coupled to KMT2A‐associated H3K4me3 deposition at TSC stem and cell cycle genes, providing a permissive chromatin environment for ...
Yuanyuan Huang, Zhenhua Hu, Jiali Liao, Lijun Huang, Jinyu Liu, Chen Tu, Yuchen Li, Lulu Xie, Shilei Bi, Xiaobo Fang, Jingsi Chen, Lili Du, Wei Sun, Haibin Wang, Shuang Zhang, Dunjin Chen, Zhaowei Tu   +16 more
wiley   +1 more source