Results 51 to 60 of about 48,358 (257)

Parenting Stress and Stressful Life Events Among Caregivers of Toddler Siblings of Autistic and Non‐Autistic Children

open access: yesAutism Research, EarlyView.
ABSTRACT This study measured experiences of parenting stress and stressful life events in caregivers of families with a toddler who has either an autistic or non‐autistic older sibling(s). Caregivers of toddlers (12–18 months old) with older autistic siblings (Sibs‐autism; n = 58) and toddlers with older non‐autistic siblings (Sibs‐NA; n = 46 ...
Jennifer E. Magnuson   +9 more
wiley   +1 more source

Use of antiemetics in early pregnancy 2012–2022: A cross‐sectional study

open access: yesBritish Journal of Clinical Pharmacology, EarlyView.
Aim Nausea and vomiting in pregnancy impact quality of life, yet many pregnant women feel dismissed by healthcare professionals, despite the safety of first‐line antiemetic treatments for both mother and fetus. Therefore, this study aims to describe the prevalence of patient‐reported antiemetic use in early pregnancy in Copenhagen, Denmark, the changes
Katrine Bak Wraae   +6 more
wiley   +1 more source

Identification of major congenital malformations based on healthcare databases in France: A proof‐of‐concept study using the epi‐meres nationwide mother–child register

open access: yesBritish Journal of Clinical Pharmacology, EarlyView.
Abstract Aim Besides registries, healthcare databases can provide useful information for assessing the frequency of major congenital malformations (MCMs) and investigating their risk factors, particularly medication exposures. This study aimed to assess the validity of MCMs identification based on French national, comprehensive healthcare databases ...
Tom Duchemin   +7 more
wiley   +1 more source

Tetraspanin‐ESCRT sorting drives miR‐29b packaging into extracellular vesicles to reverse fibrosis in intrauterine adhesions

open access: yesBMEMat, EarlyView.
MiR‐29b is enriched in extracellular vesicles (EVs) via a tetraspanin transporter‐dependent endocytosis and sorting complex required for the endosomal transport (ESCRT)‐dependent pathway. These EVs target the 3′ untranslated region (3′UTR) of TGFB2, thereby inhibiting the TGF‐β/Smad3 signaling pathway and repairing endometrial damage in intrauterine ...
Lihao Chen   +10 more
wiley   +1 more source

Humans are not unique: difficult birth is common in placental mammals

open access: yesBiological Reviews, EarlyView.
ABSTRACT Human childbirth is widely presumed to be uniquely difficult and dangerous compared to birth in other mammals. Tight fetopelvic proportions can result in obstructed labour and contribute to high rates of maternal and neonatal mortality. Ideas summarised under the ‘obstetrical dilemma’ have contributed to this assumption by explaining difficult
Nicole D. S. Grunstra
wiley   +1 more source

Maternal region of birth and stillbirth trends in Victoria, Australia, 2012–2019: a cohort study

open access: yesBMJ Public Health
Introduction Given the increasing attention to reduce stillbirth rates in migrant women and variable clinical guidance, we quantified contemporary trends in stillbirth based on maternal region of birth.Methods Population-based study of singleton births ...
Miranda Davies-Tuck   +6 more
doaj   +1 more source

Oocyte–cumulus cell interaction: a key factor in early embryo development

open access: yesBiological Reviews, EarlyView.
ABSTRACT The evaluation of oocyte competence is a fundamental step in achieving successful outcomes following assisted reproduction techniques (ART). At present, however, conventional oocyte maturation assessment is carried out by morphological observation, which is a subjective method that does not consider molecular features.
Marc Torres‐Garrido   +2 more
wiley   +1 more source

Stillbirth: Perceptions among hospital staff in the Middle East and the UK

open access: yesEuropean Journal of Obstetrics & Gynecology and Reproductive Biology: X, 2019
Objectives Stillbirth is an important and yet relatively unacknowledged public health concern in many parts of the world. Public awareness of stillbirth and its potentially modifiable risk factors is a prerequisite to planning prevention measures ...
Suruchi Mohan   +6 more
doaj   +1 more source

Did the French pregnancy pictogram change antiseizure medication use during pregnancy?

open access: yesEpilepsia, EarlyView.
Abstract Objective The aim of this study was to assess the impact of introducing a pregnancy pictogram on medication packaging on the prescription and dispensation of antiseizure medications and on the maternal and neonatal outcomes for women exposed to these medications.
Mélanie Araujo   +7 more
wiley   +1 more source

A Comprehensive Review on Nutrition, Phytochemistry, Pharmacology and Food Application Perspectives of Bioactive Rich Superfruits

open access: yesFuture Postharvest and Food, EarlyView.
The review critically evaluated and compared the selected superfruit phytochemistry, their bioactive composition and the key health benefits majorly emphasizing the antioxidant potential. It has highlighted the translational challenges in formulating functional foods by addressing the issues related to delivery system, bioavailability mechanism and the
Sharath Kumar Nagaraja   +3 more
wiley   +1 more source

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