Results 91 to 100 of about 263,271 (408)

Organoids in pediatric cancer research

FEBS Letters, EarlyView.
Organoid technology has revolutionized cancer research, yet its application in pediatric oncology remains limited. Recent advances have enabled the development of pediatric tumor organoids, offering new insights into disease biology, treatment response, and interactions with the tumor microenvironment.
Carla Ríos Arceo, Jarno Drost
wiley   +1 more source

Reciprocal control of viral infection and phosphoinositide dynamics

FEBS Letters, EarlyView.
Phosphoinositides, although scarce, regulate key cellular processes, including membrane dynamics and signaling. Viruses exploit these lipids to support their entry, replication, assembly, and egress. The central role of phosphoinositides in infection highlights phosphoinositide metabolism as a promising antiviral target.
Marie Déborah Bancilhon, Bruno Mesmin
wiley   +1 more source

Men and women from the STRIDE clinical trial: An assessment of stimulant abstinence symptom severity at residential treatment entry [PDF]

, 2015
Background and Objectives Gender‐specific factors associated with stimulant abstinence severity were examined in a stimulant abusing or dependent residential treatment sample (N = 302).
Burrow, Allison, Carmody, Thomas, Chartier, Karen G., Greer, Tracy L., Killeen, Therese K., Sanchez, Katherine, Trivedi, Madhukar H.   +6 more
core   +2 more sources

Stimulants for paediatricians [PDF]

Archives of Disease in Childhood, 2005
Does your paediatrician have difficulty concentrating during lectures, particularly those on molecular biology and healthcare planning? When taking a history, does your paediatrician not listen properly and keep asking the same questions? Is your paediatrician too busy to spend any time with his or her own children?
D, Isaacs, D A, Fitzgerald
openaire   +2 more sources

Spatiotemporal and quantitative analyses of phosphoinositides – fluorescent probe—and mass spectrometry‐based approaches

FEBS Letters, EarlyView.
Fluorescent probes allow dynamic visualization of phosphoinositides in living cells (left), whereas mass spectrometry provides high‐sensitivity, isomer‐resolved quantitation (right). Their synergistic use captures complementary aspects of lipid signaling. This review illustrates how these approaches reveal the spatiotemporal regulation and quantitative
Hiroaki Kajiho, Shin Morioka, Junko Sasaki, Takehiko Sasaki   +3 more
wiley   +1 more source

What Drives the Non-Medical Use of Stimulants Among College Students? The Role of Self-Efficacy and Attitudes: A Cross-Sectional Study of Israeli Undergraduates

European Journal of Investigation in Health, Psychology and Education
Background: Non-medical use of prescription stimulants is increasing among college students worldwide. While intended for ADHD treatment, many students use these substances to improve their concentration and academic performance. Despite global research,
Keren Dopelt, Shiran Bord, Nourit Houminer-Klepar   +2 more
doaj   +1 more source

Investigation of Personality Traits and Frequency of Personality Disorders in individuals with Stimulant and Opiate dependence. [PDF]

Journal of Advanced Biomedical Sciences, 2020
Background & Objective: In conceptualizing addiction, the role of personality elements in the emergence and continuation of dependence to substances has attracted the attention of researchers. Accordingly, the purpose of this study was to investigate the
ValiOlah Akbari, Parvin RahmatiNejad, Arman Zarghami, Seyed Davood Mohammadi   +3 more
doaj  

Increases in use of novel synthetic stimulant are not directly linked to decreased use of 3,4-methylenedioxy-N-methylamphetamine (MDMA) [PDF]

, 2013
A decline in 3,4-methylenedioxy-N-methylamphetamine (MDMA) use in Adelaide, Australia from 2009 to 2010 was confirmed by us previously. Reports suggested that the shortage in MDMA supply was associated with an increased prevalence of other synthetic ...
Chen, C., Irvine, R., Kostakis, C., White, J.   +3 more
core   +1 more source

Phosphatidylinositol 4‐kinase as a target of pathogens—friend or foe?

FEBS Letters, EarlyView.
This graphical summary illustrates the roles of phosphatidylinositol 4‐kinases (PI4Ks). PI4Ks regulate key cellular processes and can be hijacked by pathogens, such as viruses, bacteria and parasites, to support their intracellular replication. Their dual role as essential host enzymes and pathogen cofactors makes them promising drug targets.
Ana C. Mendes, Guilherme M. Azevedo, Amanda P. Barcellos, Diana Bahia   +3 more
wiley   +1 more source

Naloxone reversal of the cardiorespiratory depressant effects of opioids and mixtures of opioids and stimulants in rats

Frontiers in Pharmacology
Co-use of opioids (e.g., fentanyl) and stimulants (e.g., methamphetamine; METH) contributed to >30% of the almost 106,000 fatal overdoses in the United States in 2023.
Jacqueline M. Vazquez, Robert W. Seaman, Drew Caldron, Gregory T. Collins, Gregory T. Collins   +4 more
doaj   +1 more source