Results 211 to 220 of about 926,929 (223)

Biodegradable Guided Bone Regeneration Membranes for Periodontal Regeneration in Dogs. [PDF]

Dent J (Basel)
Costa Pinho L, Santos C, Fernandes MH, Colaço B.   +3 more
europepmc   +1 more source

Finding novel vulnerabilities of hypomorphic BRCA1 alleles

Molecular Oncology, EarlyView.
Synthetic lethality screens performed to identify novel vulnerabilities often model complete gene loss, thereby overlooking patient‐derived hypomorphic mutations. In this study, we have performed genome‐wide CRISPR screens on BRCA1 hypomorphic mutations, showing BRCA1I26A behaves like wild‐type, while BRCA1R1699Q mimics deficiency. Furthermore, we have
Anne Schreuder, Klaas de Lint, Hồ Mỹ Phúc Võ, Mariana M. Góis, Rosalie A. Kampen, Marta San Martin Alonso, Ilse Nootenboom, Veronica Garzero, Tiemen J. Wendel, Rob M. F. Wolthuis, Sylvie M. Noordermeer   +10 more
wiley   +1 more source

TRPV4-driven ATP release activates CFTR through ADORA2B and P2RY2 receptors in the airway epithelium. [PDF]

iScience
Genovese M, De Santis M, Giordano A, Marotta P, Galietta LJV.   +4 more
europepmc   +1 more source

MITF maintains genome stability in nonmelanocyte lineages

Molecular Oncology, EarlyView.
MITF is essential for melanocyte survival and acts as an oncogene in 10%–20% of melanomas. We show that MITF depletion causes genome instability in nonmelanocytic cells, leading to LATS2‐mediated P53 activation, cell cycle arrest, and apoptosis. This study highlights the role of MITF as a genome maintenance factor beyond the melanocyte lineage. Created
Drifa H. Gudmundsdottir, Adrián López García de Lomana, Thejus B. Venkatesh, Kritika Kirty, Snaevar Sigurdsson, Linda Vidarsdottir, Ramile Dilshat, Erla Sveinbjornsdottir, Snaedis Ragnarsdottir, Daniel H Magnusson, Maria R. Bustos, Eirikur Steingrimsson, Thorkell Gudjonsson, Stefan Sigurdsson   +13 more
wiley   +1 more source

Superficial heat therapy in women's health. [PDF]

Front Med (Lausanne)
Puhakka A, Mechsner S, Placek K, Reis JL, Saccone G, Cagnacci A.   +5 more
europepmc   +1 more source

TG-interacting factor 1 mediates TNF-induced Ccl2 expression in adipocytes to promote prostate cancer progression. [PDF]

FEBS Lett
Huang KH, Tsai HW, Chu YP, Chang YH, Liu XL, Tsai WL, Huang HS.   +6 more
europepmc   +1 more source

Scalable bioreactor manufacturing of iPSC-derived megakaryocytes with Proanthocyanidin A supplementation: a strategic platform for military blood supply resilience. [PDF]

Mil Med Res
Dettmer R, Rovai A, Wolkers W, Blasczyk R, Figueiredo C.   +4 more
europepmc   +1 more source

Use of a Serum With the Infinite Glow® Device Improves Signs of Facial Aging: A Split-Face Case Report Using VISIA Analysis. [PDF]

Cureus
Rodríguez D, Rodríguez M, Andersen C.
europepmc   +1 more source

The Invisible Balance: How Prebiotics and Probiotics Can Support Fish Health and Development. [PDF]

Life (Basel)
Stan HI, Barbacariu CA, Simeanu C, Radu-Rusu CG, Mircea L, Simeanu D.   +5 more
europepmc   +1 more source

Effects of yeast, tannin, and amylolytic enzyme combinations in high-concentrate diets on feed intake, nutrient digestibility, and serum metabolites in Lambs. [PDF]

Trop Anim Health Prod
Vilaça LEG, Schultz EB, de Oliveira MR, Oliveira KA, Siqueira MTS, Ribeiro PHC, Júnior GLM.   +6 more
europepmc   +1 more source