Results 171 to 180 of about 2,008,819 (319)

Long‐term hippocampal alterations and cognitive impairment in a murine model of surgical sepsis

FEBS Open Bio, EarlyView.
Using a mouse model of surgical sepsis, we tested long‐term memory and analyzed the transcriptome of single cells isolated from the hippocampus. Survivor mice showed worse memory, loss of certain brain cell subpopulations, and abnormal immune cell activity—suggesting that post‐sepsis brain alterations may be linked to cognitive deficits.
Dong Seong Cho, Rebecca Schmitt, Aneesha Dasgupta, Alexandra Ducharme, Jason Doles   +4 more
wiley   +1 more source

Motion sickness and migraine: optokinetic stimulation increases scalp tenderness, pain sensitivity in the fingers and photophobia

, 2002
The aim of this study was to determine whether scalp tenderness and photophobia, two well-recognized symptoms of migraine, develop during the motion sickness induced by optokinetic stimulation.
Drummond, P.D.
core  

Identifying transcription factors controlling the basal expression of human MRP4 highlights a substantial role for Sp1

FEBS Open Bio, EarlyView.
The MRP4 transporter exports several drugs and signaling molecules. Here, we identified key promoter elements regulating basal MRP4 expression. Using reporter assays, we defined a conserved region with essential Sp1 and contributory Ets sites, which controlled basal MRP4 expression.
Debora Singer, Angelique Kragl, Katrin Ziems, Juliane Glaubitz, Sophie Grammbauer, Susanne Hildebrandt, Mladen V. Tzvetkov, Gabriele Jedlitschky   +7 more
wiley   +1 more source

Ambient Music Decreases EEG Burst-Suppression Ratio During General Anesthesia in Rats. [PDF]

Sensors (Basel)
Morozan VP, Stancu M, Pâslaru AC, Pavel B, Mocanu A, Călin A, Zăgrean L, Zăgrean AM, Moldovan M.   +8 more
europepmc   +1 more source

Acute caffeine treatment protects the developing retina from ischemia‐induced cell death

FEBS Open Bio, EarlyView.
Caffeine reduces cell death in the developing retina under ischemia (OGD). This effect does not involve BDNF upregulation or antioxidant pathways (NRF2/VEGF). Neuroprotection occurs mainly through adenosine A2A receptor antagonism, decreasing glutamate release and excitotoxicity, highlighting caffeine's potential as an acute neuroprotective agent in ...
Amanda Alves Nascimento, Danniel Pereira‐Figueiredo, Gabriella Grossi de Lima Dias, Gabriel Ferreira dos Santos, Mariana Rodrigues Pereira, Rafael Brito, Karin C Calaza   +6 more
wiley   +1 more source

Numerical investigation of the electric field distribution induced in the brain by transcranial magnetic stimulation (TMS)

, 2004
Introduction.There has been considerable interest over the years in the treatment of serious physiological and clinical conditions, such as depression and pain relief, byutilising electromagnetic fields through Transcranial Magnetic Stimulation (TMS) of ...
Georghiou, G.E., Kim, D., Loukaides, N., Georghiou, G. E., Sykulski, J.K., Kim, Dong-Hun   +5 more
core  

Stimulation priming and psychological state shape functional connectivity following prefrontal theta-burst stimulation. [PDF]

Imaging Neurosci (Camb)
De Smet S, Wu GR, Klooster DCW, Catoira B, De Witte S, Razza LB, van de Ven V, Sack AT, Baeken C, Vanderhasselt MA.   +9 more
europepmc   +1 more source

Pharmacological inhibition of the PERK pathway modulates hepatocellular carcinoma growth and immune signaling

FEBS Open Bio, EarlyView.
Pharmacological inhibition of PERK in a DEN‐induced mouse model of liver cancer does not reduce tumor burden but alters cellular stress signaling. Despite blocking PERK activity, downstream stress responses, including CHOP expression, remain active, suggesting compensatory mechanisms within the unfolded protein response that may influence tumor ...
Ada Lerma‐Clavero, Maria Kopsida, Nathalie Arendt, Hans Lennernäs, Markus Sjöblom, Femke Heindryckx   +5 more
wiley   +1 more source

EFFECTS OF ACOUSTIC STIMULATION ON BIOPHYSICAL PROFILE TESTING TIME [PDF]

Biophysical profile (BPP) test is the most commonly used antenatal test of fetal well-being. Purpose of this study is determining the influence of acoustic stimulation (AS) on BPP testing time.
رفاهی, سهیلا, جاوید مجد, مریم, مردی, افروز, پورعیسی, مسعود   +3 more
core  

Effects of striatal transcranial temporal interference stimulation on motor learning after a traumatic brain injury

Traumatic Brain Injury (TBI) is a prevalent neurological condition that follows an externally induced cerebral lesion and is often characterized by impaired cognitive functions.
Nouri, Aria, Schaller, Karl, Léger, Bertrand, Natale, M, Ploumitsakou, Maria, Wessel, Maximilian J., Beanato, Elena, Vassiliadis, Pierre, Maceira-Elvira, Pablo, Hummel, Friedhelm C., Windel, Fabienne, Nencha, Umberto   +11 more
core   +1 more source