Results 201 to 210 of about 5,580,781 (423)

BMP antagonist CHRDL2 enhances the cancer stem‐cell phenotype and increases chemotherapy resistance in colorectal cancer

Molecular Oncology, EarlyView.
Overexpression of CHRDL2 in colon cancer cells makes them more stem‐like and resistant to chemo‐ and radiotherapy. CHRDL2‐high cells have upregulation of the WNT pathway, genes involved in the DNA damage response (DDR) pathway and epithelial‐to‐mesenchymal transition (EMT). This leads to quicker repair of damaged DNA and more cell migration.
Eloise Clarkson, Annabelle Lewis
wiley   +1 more source

Stimulation of Lettuce Seed Germination by 6-(Substituted) Purines [PDF]

, 1959
Charles G. Skinner, William Shive
openalex   +1 more source

Simultaneous inhibition of TRIM24 and TRIM28 sensitises prostate cancer cells to antiandrogen therapy, decreasing VEGF signalling and angiogenesis

Molecular Oncology, EarlyView.
TRIM24 and TRIM28 are androgen receptor (AR) coregulators which exhibit increased expression with cancer progression. Both TRIM24 and TRIM28 combine to influence the response of castrate‐resistant prostate cancer (CRPC) cells to AR inhibitors by mediating AR signalling, regulation of MYC and upregulating VEGF to promote angiogenesis. Castrate‐resistant
Damien A. Leach, Nilesh Chatterjee, Kellie Spahr, Gilberto Serrano de Almeida, Anabel Varela‐Carver, Taimur T. Shah, Mathias Winkler, Hashim U. Ahmed, Charlotte L. Bevan   +8 more
wiley   +1 more source

Evaluation of Plasma Erythropoietic-Stimulating Factors in Anemic Uremic Patients

, 1959
N. I. Gallagher, John McCarthy, Kathleen T. Hart, Robert D. Lange   +3 more
openalex   +1 more source

THE POSTMORTEM RIGOR OF THE MAMMALIAN HEART AND THE INFLUENCE OF AN ANTEMORTEM STIMULATION OF THE PNEUMOGASTRIC NERVES UPON ITS DEVELOPMENT [PDF]

, 1909
Don R. Joseph, S. J. Meltzer
openalex   +1 more source

Deep brain stimulation: current challenges and future directions

Nature Reviews Neurology, 2019
A. Lozano, N. Lipsman, H. Bergman, P. Brown, S. Chabardès, J. Chang, K. Matthews, C. McIntyre, T. Schlaepfer, M. Schulder, Y. Temel, J. Volkmann, J. Krauss   +12 more
semanticscholar   +1 more source

Understanding and measuring mechanical signals in the tumor stroma

FEBS Open Bio, EarlyView.
This review discusses cancer‐associated fibroblast subtypes and their functions, particularly in relation to extracellular matrix production, as well as the development of 3D models to study tumor stroma mechanics in vitro. Several quantitative techniques to measure tissue mechanical properties are also described, to emphasize the diagnostic and ...
Fàtima de la Jara Ortiz, Chiara Cimmino, Maurizio Ventre, Alessandra Cambi   +3 more
wiley   +1 more source

Further Observations on Lipide Stimulation of Bacterial Growth

, 1959
Klaus Hofmann, William M. O’Leary, Clayton W. Yoho, Teh‐Yung Liu   +3 more
openalex   +1 more source

Stimulation of Seedling Growth by Seed Treatments with N-Phenyl Succinimide Derivatives [PDF]

, 1952
S. E. Allen, Folke Skoog
openalex   +1 more source

Mapping Hsp104 interactions using cross‐linking mass spectrometry

FEBS Open Bio, EarlyView.
This study examines how cross‐linking mass spectrometry can be utilized to analyze ATP‐induced conformational changes in Hsp104 and its interactions with substrates. We developed an analytical pipeline to distinguish between intra‐ and inter‐subunit contacts within the hexameric homo‐oligomer and discovered contacts between Hsp104 and a selected ...
Kinga Westphal, Karolina Michalska, Andrzej Joachimiak, Lukasz A. Joachimiak   +3 more
wiley   +1 more source