Results 231 to 240 of about 4,214,353 (299)

Multi‐omics and low‐input proteomics profiling reveals dynamic regulation driving pluripotency initiation in early mouse embryos

FEBS Open Bio, EarlyView.
Mouse pre‐implantation development involves a transition from totipotency to pluripotency. Integrating transcriptomics, epigenetic profiling, low‐input proteomics and functional assays, we show that eight‐cell embryos retain residual totipotency features, whereas cytoskeletal remodeling regulated by the ubiquitin‐proteasome system drives progression ...
Wanqiong Li, Xi Xiao, Lingbin Qi, Chanyi Li, Sirui Song, Jiaying Qin, Zhigang Xue, Jinfeng Xue, Huaifang Li   +8 more
wiley   +1 more source

Advances in therapeutic hybrid neuromodulation for Parkinson's disease. [PDF]

3 Biotech
Bano I, Jeevanandam J, Tsenov G.
europepmc   +1 more source

HIV‐1 establishes immediate latency in T cells expressing the viral Nef protein

FEBS Open Bio, EarlyView.
Nef is a viral protein often omitted from HIV‐1 reporter viruses. Consequently, its role in viral latency is unclear. We developed three novel dual reporter HIV‐1 derivatives that express Nef and allow for detection of latent and productive infection. Using these reporters, we show that Nef does not affect the establishment of immediate viral latency ...
Cindy Lam, Ivan Sadowski
wiley   +1 more source

Electroacupuncture mitigates Bacillus Calmette-Guérin (BCG)-induced depression-like behavior and neuroinflammation via BDNF and NF-κB pathway in mice. [PDF]

Anim Cells Syst (Seoul)
Lee B, Kim Y, Lee HC, Kim H, Hahm DH.
europepmc   +1 more source

Alcohol‐induced altered glycans in human tracheal epithelial cells promote bacterial adhesion

FEBS Open Bio, EarlyView.
Alcohol induces altered glycans to promote bacteria adhesion. Heavy alcohol drinking is known to increase the risk of bacterial pneumonia. However, the link between alcohol levels and risk of infection remains underexplored. Recently, we found that alcohol induced α2‐6sialo mucin O‐glycans in human tracheobronchial epithelial cells, which mediated the ...
Pi‐Wan Cheng, Souvik Datta, Derrick R. Samuelson   +2 more
wiley   +1 more source

Research progress on transcranial direct current stimulation for improving muscle strength: a narrative review. [PDF]

Front Neurol
Zhang Y, Zhang Y, Song Y, Wu H, Gao X, Dong Y, Jiang N.   +6 more
europepmc   +1 more source

Adaptive deep brain stimulation for Parkinson’s disease using motor cortex sensing

Journal of Neural Engineering, 2018
Nicole C. Swann, C. de Hemptinne, Margaret C. Thompson, S. Miocinovic, Andrew M. Miller, Ro’ee Gilron, J. Ostrem, H. Chizeck, P. Starr   +8 more
semanticscholar   +1 more source

Probiotic Bifidobacterium species: potential beneficial effects in diarrheal disorders. Focus on “Probiotic Bifidobacterium species stimulate human SLC26A3 gene function and expression in intestinal epithelial cells”

, 2014
Debolina Ray, Gianfranco Alpini, Shannon Glaser   +2 more
openalex   +2 more sources

Dihydroorotate dehydrogenase (DHODH) regulates trophoblast syncytialization through organelle stress–induced cellular senescence

FEBS Open Bio, EarlyView.
The inhibition of mitochondrial dihydroorotate dehydrogenase (DHODH) impairs syncytialization and induces cellular senescence via mitochondrial and endoplasmic reticulum stress in human trophoblast stem cells, elevating sFlt1/PlGF levels, a hallmark of placental dysfunction in hypertensive disorders of pregnancy.
Kanoko Yoshida, Kazuya Kusama, Ayaka Horiuchi, Yu Kawaguchi, Atsuya Tsuru, Mikihiro Yoshie, Kazuhiro Tamura   +6 more
wiley   +1 more source

The electric brain: approach to suboptimal DBS parameters. [PDF]

Clin Park Relat Disord
Moraes de Falcone AC, França C, Guimarães TG, Cury RG.   +3 more
europepmc   +1 more source