Results 51 to 60 of about 976,503 (314)

Intelligent stimuli-responsive materials : from well-defined nanostructures to applications [PDF]

open access: yes, 2014
Book ...
Schenning, APHJ Albert   +2 more
core   +2 more sources

Nutrient/TOR signaling controls adipose mitochondrial transcription factor A (TFAM) to regulate organismal growth in Drosophila

open access: yesFEBS Letters, EarlyView.
Animals must match their growth rate to available nutrients. We show that in Drosophila larvae, the nutrient‐sensing TOR kinase controls growth by regulating levels of TFAM, a key regulator of mitochondrial function, in the adipose tissue. When nutrients are abundant, high TOR activity suppresses TFAM, lowering mitochondrial bioenergetic activity and ...
Shrivani Sriskanthadevan‐Pirahas   +4 more
wiley   +1 more source

Engineering peptides into antibodies—opportunities and strategies for therapeutic innovation

open access: yesFEBS Letters, EarlyView.
Peptides and antibodies occupy complementary therapeutic niches. Peptides recognize difficult targets in a compact format, while antibodies add specificity, long half‐life, and effector functions. This review examines strategies that merge both modalities—peptide grafting into loops, terminal and Fc fusions, and bioconjugation—highlighting how ...
Jinling Wang   +2 more
wiley   +1 more source

Unlocking the potential of stimuli‐responsive liquid crystal polymer bio‐interfaces for adaptive cell modulation

open access: yesResponsive Materials
This Perspective discusses the potential of stimuli‐responsive liquid crystal polymer (LCP) bio‐interfaces in modulating cell behavior as next generation dynamic artificial scaffolds.
Ruth M. C. Verbroekken   +2 more
doaj   +1 more source

Liver organoids: modelling complexity in homeostasis and disease

open access: yesFEBS Letters, EarlyView.
Studying liver in vitro has been challenging because simple 2D cell cultures fail to capture liver's cellular and architectural complexity. To bridge this gap, scientists increasingly use organoids, 3D liver models which better mimic liver composition and function. This review examines recent advances in liver organoid complexity and realism, discusses
Anna M. Dowbaj, Meritxell Huch
wiley   +1 more source

Stimuli-Responsive Assemblies for Sensing Applications [PDF]

open access: yesGels, 2016
Poly (N-isopropylacrylamide) (pNIPAm)-based hydrogels and hydrogel particles (microgels) have been extensively studied since their discovery a number of decades ago. While their utility seems to have no limit, this feature article is focused on their development and application for sensing small molecules, macromolecules, and biomolecules. We highlight
Li, Xue   +2 more
openaire   +4 more sources

Epigenetic reprogramming of lineage switching in cancer

open access: yesFEBS Letters, EarlyView.
Cancer cells rarely commit to a single identity. Epigenetic mechanisms and tumor microenvironment cues push epithelial cells toward flexible, hybrid states that can shift into mesenchymal, neuroendocrine, or stem‐like fates, driving metastasis, drug resistance, and tumor heterogeneity. Targeting the epigenetic regulators behind these transitions, using
Ezgi Boyvatlı   +4 more
wiley   +1 more source

Trojan‐Horse‐Like Stimuli‐Responsive Microcapsules

open access: yesAdvanced Science, 2018
Multicompartment microcapsules, with each compartment protected by a distinct stimuli‐responsive shell for versatile controlled release, are highly desired for developing new‐generation microcarriers.
Chuan‐Lin Mou   +8 more
doaj   +1 more source

Molecularly Imprinted Nanomaterials with Stimuli Responsiveness for Applications in Biomedicine

open access: yesMolecules, 2023
The review aims to summarize recent reports of stimuli-responsive nanomaterials based on molecularly imprinted polymers (MIPs) and discuss their applications in biomedicine.
Yan Zhang   +5 more
doaj   +1 more source

Stimuli-responsive microgel-based etalons for optical sensing

open access: yes, 2015
Responsive polymer-based materials (or smart materials) have found numerous uses over the years due to their ease of synthesis and various responsivities/functionalities.
Li, Xue   +2 more
core   +1 more source

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