Heterodimeric amino acid transporters consist of SLC7 and SLC3 family proteins arranged in a conserved structural organization. They regulate nutrient transport across cell membranes, supporting essential cellular functions. These transporters also contribute to xenobiotic/drug uptake and distribution.
Mariafrancesca Scalise +5 more
wiley +1 more source
Stimuli‐Responsive Phosphorus‐Based Polymers [PDF]
This microreview details recent developments in stimuli‐responsive polymers with phosphorus in the main‐chain, in particular polyphosphazenes and polyphosphoesters. The presence of phosphorus in the polymers endows unique properties onto the macromolecules, which can be utilized for the preparation of materials capable of physically responding to ...
openaire +2 more sources
Metastatic niche shaped by host factors influences disseminated cancer cell fate
Metastasis is shaped not only by cancer cells but also by the environments they encounter. This review explores how factors such as aging, diet, the microbiome, lifestyle, and environmental exposures remodel organ‐specific niches in the lung, liver, bone, and brain, influencing where metastatic cells survive, remain dormant, or grow, and ultimately ...
Gwennan Delyth Ward +2 more
wiley +1 more source
Stimuli-Responsive Conformational Transformation of Peptides for Tunable Cytotoxicity
The stimuli-responsive conformational transformation of peptides possessing a constrained form triggered by specific biological microenvironment would provide an effective strategy for the development of highly specific peptide therapeutics.
Hanwool Lee (8196267) +13 more
core +1 more source
Inhibition of dipeptidyl peptidase 7 impairs lysophagy in LLOMe‐treated HepG2 cells
DPP7 inhibition delays ubiquitin‐dependent lysophagy by attenuating ubiquitin accumulation and the recruitment of SQSTM1 and LC3 to damaged lysosomes, resulting in delayed clearance of damaged lysosomes and impaired restoration of lysosomal homeostasis. Created using FigureLabs (Certificate ID: FL‐PUB‐20260922‐Z99XNX).
Na Yeon Park +8 more
wiley +1 more source
Advances in biomimetic stimuli responsive soft grippers
A variety of biomimetic stimuli-responsive soft grippers that can be utilized as intelligent actuators, sensors, or biomedical tools have been developed.
ChangKyu Yoon
doaj +1 more source
Stimuli-Responsive Polymer Systems—Recent Manufacturing Techniques and Applications
Stimuli-Responsive Polymer Systems—Recent Manufacturing Techniques and ...
Lib Figshare RT (13039398)
core
Multi-Stimuli-Responsive Polymer/Inorganic Janus Composite Nanoparticles
Multi-stimuli-responsive Janus composite nanoparticles (JNPs) of poly(N-isopropylacrylamide)–Fe3O4–poly(2-(dimethylamino)ethyl methacrylate)) (PNIPAM–Fe3O4–PDMEAMA) are synthesized by sequential reversible addition–fragmentation chain-transfer ...
Zhengran Yi +7 more
core +1 more source
The role of miR‐335‐5p in the redifferentiation of BRAF p.V600E thyroid cancers
The BRAF p.V600E mutation promotes thyroid cancer dedifferentiation and radioiodine resistance. Using a network approach, we identified miR‐335‐5p as a key regulator of BRAF‐mutated thyroid tumors. Restoring miR‐335‐5p increased thyroid‐specific gene expression and iodine uptake in cells and organoids.
Valeria Pecce +11 more
wiley +1 more source
Stimuli-responsive polymer film or coating prepared by mixing in a suitable fashion a side chain liquid crystalline polymer with reactive mesogens and responsive devices: process for preparing the same [PDF]
The limitation of the different classes of responsive liquid crystals such as volatility in case of low molecular weight liquid crystals (LMWLCs) can be overcome by the development of a responsive film based on polymerliquid crystals (PLCs) and reactive ...
core

