Results 61 to 70 of about 585,821 (290)
eXPRESS Polymer Letters, 2022 With the increasing demand for liquid manipulation and microfluidic techniques, surfaces with external stimuli induced real-time tunable wetting properties are getting into the focus of materials science research.
László Mérai +5 more
doaj +1 more source
FEBS Letters, EarlyView.Inositol pyrophosphates are energy‐rich signaling molecules that perform critical functions in cells. Three different families of phosphatases hydrolyze the β phosphate of the inositol pyrophosphate molecules: two have narrow specificities and one is promiscuous.
Ronda J. Rolfes
wiley +1 more source
Cell Reports Physical Science, 2020 Summary: The transfer of molecular machine technology into aggregated states is a key step for the realization of many potential applications. Here we report three organic luminescent agents, CzS-o-py, CzS-m-py, and CzS-p-py, that can adjust organic room-
Yu Tian +7 more
doaj +1 more source
Light-Modulated Rheological Properties in Green Innovative Formulations
Substantia, 2022 The addition of azorubine to a viscoelastic aqueous dispersion of sodium oleate (NaOL, 0.43 M, 13% w/w) and KCl (up to 4% w/w) leads to a green gel-like system whose rheological behavior can be efficiently and reversibly triggered from remote by using ...
Duccio Tatini +2 more
doaj +1 more source
Investigating transcription factor dynamics in health and disease using FRAP
FEBS Letters, EarlyView.FRAP analysis of GFP‐tagged transcription factors reveals how molecular mobility and target engagement change in response to drug treatment. By combining live‐cell imaging, quantitative model fitting, and statistical analysis, this approach uncovers transcription factor dynamics linked to disease mechanisms, providing a powerful framework for ...
Kannan Govindaraj +3 more
wiley +1 more source
Recent Advances in Nanomicelles Delivery Systems
Nanomaterials, 2020 The efficient and selective delivery of therapeutic drugs to the target site remains the main obstacle in the development of new drugs and therapeutic interventions.
Salah M. Tawfik +4 more
doaj +1 more source
The role of miR‐335‐5p in the redifferentiation of BRAF p.V600E thyroid cancers
Molecular Oncology, EarlyView.The BRAF p.V600E mutation promotes thyroid cancer dedifferentiation and radioiodine resistance. Using a network approach, we identified miR‐335‐5p as a key regulator of BRAF‐mutated thyroid tumors. Restoring miR‐335‐5p increased thyroid‐specific gene expression and iodine uptake in cells and organoids.
Valeria Pecce +11 more
wiley +1 more source
Tumour–host interactions in Drosophila: mechanisms in the tumour micro‐ and macroenvironment
Molecular Oncology, EarlyView.This review examines how tumour–host crosstalk takes place at multiple levels of biological organisation, from local cell competition and immune crosstalk to organism‐wide metabolic and physiological collapse. Here, we integrate findings from Drosophila melanogaster studies that reveal conserved mechanisms through which tumours hijack host systems to ...
José Teles‐Reis, Tor Erik Rusten
wiley +1 more source
Stimulus, Response, Interpretation [PDF]
The Annals of Family Medicine, 2005 In this On TRACK, I consider the stimulus provided by articles in the last issue of the Annals and the response of thoughtful readers commenting in the Annals online discussion (TRACK), and I provide my own interpretation. I encourage readers to write your own interpretation as an online comment to On TRACK or the original article.
openaire +1 more source
Molecular Oncology, EarlyView.Glioma cells mainly express the endothelin receptor EDNRB, while EDNRA is restricted to a perivascular tumor subpopulation. Endothelin signaling reduces glioma cell proliferation while promoting migration and a proneural‐to‐mesenchymal transition associated with poor prognosis. This pathway activates Ca2+, K+, ERK, and STAT3 signalings and is regulated
Donovan Pineau +36 more
wiley +1 more source